| Intermittent short-duration reoxygenation relieves high-altitude pulmonary hypertension via NOX4/H2O2/PPAR-gamma axis. | Intermittent short-duration reoxygenation relieves high-altitude pulmonary hypertension via NOX4/H2O2/PPAR-γ axis.
Li S, Lyu Q, Shi Q, Bai Y, Ren X, Ma J., Free PMC Article | 02/12/2024 |
| Advanced glycated end-products inhibit dilation through constitutive endothelial RAGE and Nox1/4 in rat isolated skeletal muscle arteries. | Advanced glycated end-products inhibit dilation through constitutive endothelial RAGE and Nox1/4 in rat isolated skeletal muscle arteries.
Naser N, Lonj CK, Rikard-Bell M, Sandow SL, Murphy TV. | 01/29/2024 |
| Hypoxia stabilizes the H2 O2 -producing oxidase Nox4 in cardiomyocytes via suppressing autophagy-related lysosomal degradation. | Hypoxia stabilizes the H(2) O(2) -producing oxidase Nox4 in cardiomyocytes via suppressing autophagy-related lysosomal degradation.
Matsunaga S, Kohda A, Kamakura S, Hayase J, Miyano K, Shiose A, Sumimoto H. | 01/3/2024 |
| Interruption of TRPC6-NFATC1 signaling inhibits NADPH oxidase 4 and VSMCs phenotypic switch in intracranial aneurysm. | Interruption of TRPC6-NFATC1 signaling inhibits NADPH oxidase 4 and VSMCs phenotypic switch in intracranial aneurysm.
Sun ZH, Liu F, Kong LL, Ji PM, Huang L, Zhou HM, Sun R, Luo J, Li WZ. | 08/10/2023 |
| Maternal exercise represses Nox4 via SIRT1 to prevent vascular oxidative stress and endothelial dysfunction in SHR offspring. | Maternal exercise represses Nox4 via SIRT1 to prevent vascular oxidative stress and endothelial dysfunction in SHR offspring.
Zhang Y, Shan M, Ding X, Sun H, Qiu F, Shi L., Free PMC Article | 08/2/2023 |
| VEGF-A: A Novel Mechanistic Link Between CYP2C-Derived EETs and Nox4 in Diabetic Kidney Disease. | VEGF-A: A Novel Mechanistic Link Between CYP2C-Derived EETs and Nox4 in Diabetic Kidney Disease.
Njeim R, Braych K, Ghadieh HE, Azar NS, Azar WS, Dia B, Leone A, Cappello F, Kfoury H, Harb F, Jurjus AR, Eid AA, Ziyadeh FN. | 06/28/2023 |
| Functional Significance of Angiotensin Receptor Type 2 in the Neuroplasticity of Autonomic Ganglia in (mRen2)27 Transgenic Hypertensive Rats. | Functional Significance of Angiotensin Receptor Type 2 in the Neuroplasticity of Autonomic Ganglia in (mRen2)27 Transgenic Hypertensive Rats.
Swami Vetha BS, Byrum R, Peele K, Diz D, Aileru A., Free PMC Article | 01/28/2023 |
| Advanced oxidation protein products induce annulus fibrosus cell senescence through a NOX4-dependent, MAPK-mediated pathway and accelerate intervertebral disc degeneration. | Advanced oxidation protein products induce annulus fibrosus cell senescence through a NOX4-dependent, MAPK-mediated pathway and accelerate intervertebral disc degeneration.
Dai X, Chen Y, Yu Z, Liao C, Liu Z, Chen J, Wu Q., Free PMC Article | 01/21/2023 |
| MicroRNA-454 modulates the oxidative stress and neuronal apoptosis after cerebral ischemia/reperfusion injury via targeting NADPH oxidase 4 (NOX4). | MicroRNA-454 modulates the oxidative stress and neuronal apoptosis after cerebral ischemia/reperfusion injury via targeting NADPH oxidase 4 (NOX4).
Zhang T, Han H, Zhou Y, Liu Z, Ma T, Cao X., Free PMC Article | 10/22/2022 |
| Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition. | Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition.
Xun Y, Zhou P, Yang Y, Li C, Zhang J, Hu H, Qin B, Zhang Z, Wang Q, Lu Y, Wang S. | 04/9/2022 |
| NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria. | NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria.
Li ZY, Liu Y, Wang YY, Li X, Han ZN, Hong L, Li YS, Cui X., Free PMC Article | 04/2/2022 |
| Protective effects of metformin against myocardial ischemiareperfusion injury via AMPKdependent suppression of NOX4. | Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4.
Shi Y, Hou SA., Free PMC Article | 01/15/2022 |
| In Vivo Investigation of the Ameliorating Effect of Tempol against MIA-Induced Knee Osteoarthritis in Rats: Involvement of TGF-beta1/SMAD3/NOX4 Cue. | In Vivo Investigation of the Ameliorating Effect of Tempol against MIA-Induced Knee Osteoarthritis in Rats: Involvement of TGF-β1/SMAD3/NOX4 Cue.
Abo-Zalam HB, Abdelsalam RM, Abdel-Rahman RF, Abd-Ellah MF, Khattab MM., Free PMC Article | 12/11/2021 |
| Neuregulin-1 alleviate oxidative stress and mitigate inflammation by suppressing NOX4 and NLRP3/caspase-1 in myocardial ischaemia-reperfusion injury. | Neuregulin-1 alleviate oxidative stress and mitigate inflammation by suppressing NOX4 and NLRP3/caspase-1 in myocardial ischaemia-reperfusion injury.
Wang F, Wang H, Liu X, Yu H, Huang X, Huang W, Wang G., Free PMC Article | 09/25/2021 |
| IRE1alpha/NOX4 signaling pathway mediates ROS-dependent activation of hepatic stellate cells in NaAsO2 -induced liver fibrosis. | IRE1α/NOX4 signaling pathway mediates ROS-dependent activation of hepatic stellate cells in NaAsO(2) -induced liver fibrosis.
Tao Y, Qiu T, Yao X, Jiang L, Wang N, Jiang J, Jia X, Wei S, Zhang J, Zhu Y, Tian W, Yang G, Liu X, Liu S, Ding Y, Sun X. | 09/11/2021 |
| Overexpression of mechanical sensitive miR-337-3p alleviates ectopic ossification in rat tendinopathy model via targeting IRS1 and Nox4 of tendon-derived stem cells. | Overexpression of mechanical sensitive miR-337-3p alleviates ectopic ossification in rat tendinopathy model via targeting IRS1 and Nox4 of tendon-derived stem cells.
Geng Y, Zhao X, Xu J, Zhang X, Hu G, Fu SC, Dai K, Chen X, Patrick YS, Zhang X., Free PMC Article | 08/14/2021 |
| Galectin-3 mediates high-glucose-induced cardiomyocyte injury by the NADPH oxidase/reactive oxygen species pathway. | Galectin-3 mediates high-glucose-induced cardiomyocyte injury by the NADPH oxidase/reactive oxygen species pathway.
Sun J, Zhang L, Fang J, Yang S, Chen L. | 08/7/2021 |
| Apocynin ameliorates NADPH oxidase 4 (NOX4) induced oxidative damage in the hypoxic human retinal Muller cells and diabetic rat retina. | Apocynin ameliorates NADPH oxidase 4 (NOX4) induced oxidative damage in the hypoxic human retinal Müller cells and diabetic rat retina.
Ahmad A, Nawaz MI, Siddiquei MM, Abu El-Asrar AM. | 07/31/2021 |
| Oxymatrine Ameliorates Memory Impairment in Diabetic Rats by Regulating Oxidative Stress and Apoptosis: Involvement of NOX2/NOX4. | Oxymatrine Ameliorates Memory Impairment in Diabetic Rats by Regulating Oxidative Stress and Apoptosis: Involvement of NOX2/NOX4.
Huang Y, Li X, Zhang X, Tang J., Free PMC Article | 05/22/2021 |
| NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease. | NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease.
Pavlov TS, Palygin O, Isaeva E, Levchenko V, Khedr S, Blass G, Ilatovskaya DV, Cowley AW Jr, Staruschenko A., Free PMC Article | 04/24/2021 |
| Nox4 regulates InsP3 receptor-dependent Ca(2+) release into mitochondria to promote cell survival. | Nox4 regulates InsP(3) receptor-dependent Ca(2+) release into mitochondria to promote cell survival.
Beretta M, Santos CX, Molenaar C, Hafstad AD, Miller CC, Revazian A, Betteridge K, Schröder K, Streckfuß-Bömeke K, Doroshow JH, Fleck RA, Su TP, Belousov VV, Parsons M, Shah AM., Free PMC Article | 04/13/2021 |
| Chronic Exposure to Fluoride Affects GSH Level and NOX4 Expression in Rat Model of This Element of Neurotoxicity. | Chronic Exposure to Fluoride Affects GSH Level and NOX4 Expression in Rat Model of This Element of Neurotoxicity.
Dec K, Łukomska A, Skonieczna-Żydecka K, Jakubczyk K, Tarnowski M, Lubkowska A, Baranowska-Bosiacka I, Styburski D, Skórka-Majewicz M, Maciejewska D, Gutowska I., Free PMC Article | 03/20/2021 |
| Oxidative Stress and Mitochondrial Abnormalities Contribute to Decreased Endothelial Nitric Oxide Synthase Expression and Renal Disease Progression in Early Experimental Polycystic Kidney Disease. | Oxidative Stress and Mitochondrial Abnormalities Contribute to Decreased Endothelial Nitric Oxide Synthase Expression and Renal Disease Progression in Early Experimental Polycystic Kidney Disease.
Kahveci AS, Barnatan TT, Kahveci A, Adrian AE, Arroyo J, Eirin A, Harris PC, Lerman A, Lerman LO, Torres VE, Irazabal MV., Free PMC Article | 12/5/2020 |
| Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats. | Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats.
Li XX, Ling SK, Hu MY, Ma Y, Li Y, Huang PL. | 09/5/2020 |
| Nox2 and Nox4 mediate endothelial injury in HIV- and opioid-induced pulmonary arterial hypertension. | NADPH oxidase-mediated endothelial injury in HIV- and opioid-induced pulmonary arterial hypertension.
Agarwal S, Sharma H, Chen L, Dhillon NK., Free PMC Article | 07/25/2020 |