Circ_PWWP2A promotes lung fibroblast proliferation and fibrosis via the miR-27b-3p/GATA3 axis, thereby aggravating idiopathic pulmonary fibrosis. | Circ_PWWP2A promotes lung fibroblast proliferation and fibrosis via the miR-27b-3p/GATA3 axis, thereby aggravating idiopathic pulmonary fibrosis. Su L, Nian Y, Zhu T. | 09/22/2023 |
GATA3/long noncoding RNA MHC-R regulates the immune activity of dendritic cells in chronic obstructive pulmonary disease induced by air pollution particulate matter. | GATA3/long noncoding RNA MHC-R regulates the immune activity of dendritic cells in chronic obstructive pulmonary disease induced by air pollution particulate matter. He F, Wang N, Yu X, Zheng Y, Liu Q, Chen Q, Pu J, Li N, Zou W, Li B, Ran P. | 08/27/2022 |
we identified a novel, nonredundant role for GATA3 in MCs from their first appearance in embryonic kidney to mature glomeruli in health and disease. Furthermore, GATA3 expression increases inMCs in mesangial proliferative GN and haploinsufficiency of GATA3 results in MC defects, suggesting its importance for glomerular homeostasis and response to injury. | A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury. Grigorieva IV, Oszwald A, Grigorieva EF, Schachner H, Neudert B, Ostendorf T, Floege J, Lindenmeyer MT, Cohen CD, Panzer U, Aigner C, Schmidt A, Grosveld F, Thakker RV, Rees AJ, Kain R., Free PMC Article | 05/30/2020 |
Data indicate there is a relationship between inflammation and imbalance in the expression of fork head-like transcription factor 3 (Foxp3), T box expressed in T cells (T-bet) and GATA binding protein 3 (GATA3) in chronic obstructive pulmonary disease. | [Imbalance in the expression of Foxp3, T-bet and GATA-3 is correlated with inflammation of chronic obstructive pulmonary disease]. Wang C, Liu X, Peng Q, Li D, Ji Q, Wang C, Li Z. | 10/4/2014 |
The imbalance of transcription factor GATA-3 and T-bet has a close correlation with the eosinophil count, and may play a key role in the formation of allergic rhinitis. | [Expression of transcription factors T-bet and GATA-3 and relationship to the numbers of eosinophils in rat model of allergic rhinitis]. Yang C, Li C, Luo G, Luo Y, Liu Y. | 08/4/2012 |
Both GATA-3 and T-bet were involved in allergic rhinitis, only in different phases. | [Kinetic expression of T-bet and GATA-3 genes in rat allergic rhinitis models]. Li Y, Chen D, Li T, Wen W, Shi J, He X. | 03/17/2012 |
These results demonstrate a direct positive role of estrogen in regulating Aurora-A expression through activation of the ERalpha-GATA-3 signaling cascade | Estrogen-induced aurora kinase-A (AURKA) gene expression is activated by GATA-3 in estrogen receptor-positive breast cancer cells. Jiang S, Katayama H, Wang J, Li SA, Hong Y, Radvanyi L, Li JJ, Sen S., Free PMC Article | 12/10/2011 |
retinoid nuclear transcription factors, GATA-3 and histone acetylation/deacetylation processes may have a regulatory role to play in prestin expression. | Effects of retinoic acid and butyric acid on the expression of prestin and Gata-3 in organotypic cultures of the organ of corti of newborn rats. Gross J, Stute K, Fuchs J, Angerstein M, Amarjargal N, Mazurek B. | 10/15/2011 |
Garlicin may upregulate the expression of T-bet dramatically and downregulate the expression of transcription factor GATA-3 in the experimental models of allergic rhinitis. | [Effects of garlicin on the expression of transcription factor T-bet and GATA-3 in blood lymph cells in rats with allergic rhinitis]. Chen D, Li YX, Li TY, Wen WP, Shi JB, He XG. | 05/21/2011 |
study shows that GATA-3 plays critical roles in mediating survival signals in osteoblasts, possibly through upregulating bcl-x(L) gene expression | GATA-3 transduces survival signals in osteoblasts through upregulation of bcl-x(L) gene expression. Chen RM, Lin YL, Chou CW. | 02/26/2011 |
Imbalance of transcription factors T-bet and GATA-3 may play a key role in the formation of airway inflammation in asthma. | [Imbalanced T cell-specific transcription factors T-bet and GATA-3 and relationship to airway inflammation in asthmatic rats]. Bian T, Yin KS, Jin SX, Meng ZL, Zhou JY, Ma XQ, Hu JJ, De W. | 09/13/2010 |
There may be a regulatory role played by the Gata-3,-2 transcription factors in prestin expression. | Expression of prestin and Gata-3,-2,-1 mRNA in the rat organ of Corti during the postnatal period and in culture. Gross J, Stute K, Moller R, Fuchs J, Amarjargal N, Pohl EE, Angerstein M, Smorodchenko A, Mazurek B. | 05/31/2010 |
GATA3 expression in the CNS throughout postnatal life, and the dynamics that we observed provide insights for further investigations of the roles of GATA3 in postnatal development and the maintenance of the mature CNS. | Expression of the transcription factor GATA3 in the postnatal mouse central nervous system. Zhao GY, Li ZY, Zou HL, Hu ZL, Song NN, Zheng MH, Su CJ, Ding YQ. | 01/21/2010 |
GATA-3 play an important role in Th2 commitment during anterior chamber associated immune deviation development. | [GATA-3 in the development of anterior chamber associated immune deviation]. Fu T, Yang P, Huang X, Zhou H, Zhong H, Li B, Wang H, Zhang Z. | 01/21/2010 |