Ca2+-triggered Atg11-Bmh1/2-Snf1 complex assembly initiates autophagy upon glucose starvation. | Ca2+-triggered Atg11-Bmh1/2-Snf1 complex assembly initiates autophagy upon glucose starvation. Yao W, Chen Y, Zhang Y, Zhong S, Ye M, Chen Y, Fan S, Ye M, Yang H, Li Y, Wu C, Fan M, Feng S, He Z, Zhou L, Zhang L, Wang Y, Liu W, Tong J, Feng D, Yi C., | 07/31/2024 |
Mechanism of Atg9 recruitment by Atg11 in the cytoplasm-to-vacuole targeting pathway. | Mechanism of Atg9 recruitment by Atg11 in the cytoplasm-to-vacuole targeting pathway. Coudevylle N, Banaś B, Baumann V, Schuschnig M, Zawadzka-Kazimierczuk A, Koźmiński W, Martens S., Free PMC Article | 05/14/2022 |
Atg11-mediated activation of Atg1 kinase in fission yeast. | Atg11-mediated activation of Atg1 kinase in fission yeast. Pan ZQ, Du LL., Free PMC Article | 11/22/2021 |
TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes. | TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes. Tomioka Y, Kotani T, Kirisako H, Oikawa Y, Kimura Y, Hirano H, Ohsumi Y, Nakatogawa H., Free PMC Article | 03/20/2021 |
The Third Coiled Coil Domain of Atg11 Is Required for Shaping Mitophagy Initiation Sites. | The Third Coiled Coil Domain of Atg11 Is Required for Shaping Mitophagy Initiation Sites. Margolis HK, Katzenell S, Leary KA, Ragusa MJ., Free PMC Article | 03/6/2021 |
In yeast, Atg11 and Atg17 function as protein scaffolds, essential for selective and non-selective types of autophagy, respectively. [review] | Mechanistic Insights into the Role of Atg11 in Selective Autophagy. Zientara-Rytter K, Subramani S., Free PMC Article | 06/27/2020 |
Data show that activated autophagy protein ATG11 (Atg11) dimerizes and tethers autophagy protein ATG9 (Atg9) vesicles. | Atg11 tethers Atg9 vesicles to initiate selective autophagy. Matscheko N, Mayrhofer P, Rao Y, Beier V, Wollert T., Free PMC Article | 01/25/2020 |
Atg11 plays important roles in low-level nonselective autophagy | Induction of autophagy by phosphate starvation in an Atg11-dependent manner in Saccharomyces cerevisiae. Yokota H, Gomi K, Shintani T. | 06/10/2017 |
In vitro studies show that Atg1 kinase is activated by selective autophagy targets in yeast requiring the Atg11 scaffold. | Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase. Kamber RA, Shoemaker CJ, Denic V., Free PMC Article | 11/7/2015 |
Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation. | Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation. Mao K, Chew LH, Inoue-Aono Y, Cheong H, Nair U, Popelka H, Yip CK, Klionsky DJ., Free PMC Article | 11/30/2013 |
Selective autophagy receptors interact with two proteins of the core autophagic machinery: the scaffold protein Atg11 and the ubiquitin-like protein Atg8. | Phosphorylation of mitophagy and pexophagy receptors coordinates their interaction with Atg8 and Atg11. Farré JC, Burkenroad A, Burnett SF, Subramani S., Free PMC Article | 10/26/2013 |
When mitophagy is induced, Atg11 in turn attracts other mitochondrial fission proteins and promotes mitochondrial division. | The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy. Mao K, Wang K, Liu X, Klionsky DJ., Free PMC Article | 09/28/2013 |
ATG11 is essential for selective autophagy and mitophagy | Mitophagy in yeast occurs through a selective mechanism. Kanki T, Klionsky DJ., Free PMC Article | 01/21/2010 |
findings suggest that Atg11 plays an integral role in connecting cargo molecules with components of the vesicle-forming machinery | Atg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathway. Yorimitsu T, Klionsky DJ., Free PMC Article | 01/21/2010 |
Atg11 connecs cargoes, actin and pre-utophagosomal structure (PAS) elements. | Atg11 directs autophagosome cargoes to the PAS along actin cables. Monastyrska I, Shintani T, Klionsky DJ, Reggiori F. | 01/21/2010 |