| Urinary vanin-1 as a novel biomarker for survival in peripheral artery disease. | Urinary vanin-1 as a novel biomarker for survival in peripheral artery disease.
Zierfuss B, Karlinger A, Bojic M, Koppensteiner R, Schernthaner GH, Höbaus C., Free PMC Article | 09/23/2024 |
| Urinary vanin-1 for predicting acute pyelonephritis in young children with urinary tract infection: a pilot study. | Urinary vanin-1 for predicting acute pyelonephritis in young children with urinary tract infection: a pilot study.
Krzemień G, Pańczyk-Tomaszewska M, Górska E, Szmigielska A. | 11/27/2021 |
| Near-Infrared Fluorescent Probe for Imaging and Evaluating the Role of Vanin-1 in Chemotherapy. | Near-Infrared Fluorescent Probe for Imaging and Evaluating the Role of Vanin-1 in Chemotherapy.
Lu P, Zhang C, Fu L, Wei Y, Huang Y, Wang X, Lv C, Chen L. | 09/18/2021 |
| Pancreatic ductal deletion of S100A9 alleviates acute pancreatitis by targeting VNN1-mediated ROS release to inhibit NLRP3 activation. | Pancreatic ductal deletion of S100A9 alleviates acute pancreatitis by targeting VNN1-mediated ROS release to inhibit NLRP3 activation.
Xiang H, Guo F, Tao X, Zhou Q, Xia S, Deng D, Li L, Shang D., Free PMC Article | 07/31/2021 |
| This review discusses the role of vanin 1 in the liver, kidney, intestine, and lung under physiological as well as pathophysiological conditions. [review] | Vanin 1: Its Physiological Function and Role in Diseases.
Bartucci R, Salvati A, Olinga P, Boersma YL., Free PMC Article | 01/18/2020 |
| Urinary vanin-1 is a useful biomarker to detect and monitor the clinical course of obstructive nephropathy. | A Novel Biomarker for Acute Kidney Injury, Vanin-1, for Obstructive Nephropathy: A Prospective Cohort Pilot Study.
Washino S, Hosohata K, Oshima M, Okochi T, Konishi T, Nakamura Y, Saito K, Miyagawa T., Free PMC Article | 06/8/2019 |
| findings suggest that the metabolic pathway catalyzed by VNN1 pantetheinase plays a suppressive role in IAV infection in the respiratory tract, especially in severe conditions under hypercytokinemia | Metabolic pathway catalyzed by Vanin-1 pantetheinase plays a suppressive role in influenza virus replication in human alveolar epithelial A549 cells.
Yamashita N, Yashiro M, Ogawa H, Namba H, Nosaka N, Fujii Y, Morishima T, Tsukahara H, Yamada M. | 09/23/2017 |
| Data show that G protein-coupled receptor, family C, group 5, member A protein (GPRC5A) regulates oxidative stress through vanin 1 protein (VNN1). | Elevation of GPRC5A expression in colorectal cancer promotes tumor progression through VNN-1 induced oxidative stress.
Zhang L, Li L, Gao G, Wei G, Zheng Y, Wang C, Gao N, Zhao Y, Deng J, Chen H, Sun J, Li D, Zhang X, Liu M. | 09/23/2017 |
| These data suggest that urinary vanin-1 is an early predictive biomarker for decline in eGFR in patients with urothelial carcinoma after dosing of cisplatin | Early prediction of cisplatin-induced nephrotoxicity by urinary vanin-1 in patients with urothelial carcinoma.
Hosohata K, Washino S, Kubo T, Natsui S, Fujisaki A, Kurokawa S, Ando H, Fujimura A, Morita T. | 05/6/2017 |
| serum pantetheinas, encoded by the VNN1 gene, level regulates erythrocyte life span and modulates the risk of developing complicated malaria. | Serum pantetheinase/vanin levels regulate erythrocyte homeostasis and severity of malaria.
Rommelaere S, Millet V, Rihet P, Atwell S, Helfer E, Chasson L, Beaumont C, Chimini G, Sambo Mdo R, Viallat A, Penha-Gonçalves C, Galland F, Naquet P. | 06/4/2016 |
| VNN1 contributes to corticosteroid responsiveness, and changes in VNN1 nasal epithelial mRNA expression and VNN1 promoter methylation might be clinically useful biomarkers of treatment response in asthmatic children. | Vanin-1 expression and methylation discriminate pediatric asthma corticosteroid treatment response.
Xiao C, Biagini Myers JM, Ji H, Metz K, Martin LJ, Lindsey M, He H, Powers R, Ulm A, Ruff B, Ericksen MB, Somineni HK, Simmons J, Strait RT, Kercsmar CM, Khurana Hershey GK., Free PMC Article | 01/23/2016 |
| Our study provides strong biological evidence for the association of the identified SNP with BP and suggests that vanin-1 misfolding and degradation are the underlying molecular mechanism. | The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function.
Wang YJ, Tayo BO, Bandyopadhyay A, Wang H, Feng T, Franceschini N, Tang H, Gao J, Sung YJ, COGENT BP consortium, Elston RC, Williams SM, Cooper RS, Mu TW, Zhu X., Free PMC Article | 11/21/2015 |
| show that hepatic vanin-1 is under extremely sensitive regulation by PPARalpha and that plasma vanin activity could serve as a readout of changes in PPARalpha activity in human subjects | PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism.
van Diepen JA, Jansen PA, Ballak DB, Hijmans A, Hooiveld GJ, Rommelaere S, Galland F, Naquet P, Rutjes FP, Mensink RP, Schrauwen P, Tack CJ, Netea MG, Kersten S, Schalkwijk J, Stienstra R. | 08/15/2015 |
| The X-ray crystal structure of human vanin 1 at 2.25 A resolution is presented, which is the first reported structure from the vanin family, as well as a crystal structure of vanin 1 bound to a specific inhibitor. | The structure of vanin 1: a key enzyme linking metabolic disease and inflammation.
Boersma YL, Newman J, Adams TE, Cowieson N, Krippner G, Bozaoglu K, Peat TS. | 08/15/2015 |
| Serum vanin-1 levels may be low in the end-stage renal failure and transiently increase after transplant owing to transient renal function deterioration, which does not lead to elevation of serum creatinine levels in renal transplant patients. | Serum vanin-1 levels in renal transplant patients.
Atış Ö, Aksoy H, Keleş M, Gümüşdere M. | 12/6/2014 |
| Our results suggest that vanin-1 can distinguish between chronic responders and non-responders ITP patients as well as between newly diagnosed ITP patients and healthy controls. | Value of vanin-1 assessment in adult patients with primary immune thrombocytopenia.
Elsalakawy WA, Ali MA, Hegazy MG, Farweez BA. | 11/8/2014 |
| Alternative Splicing in VNN1 gene is associated with colorectal cancer. | A novel transcript, VNN1-AB, as a biomarker for colorectal cancer.
Løvf M, Nome T, Bruun J, Eknaes M, Bakken AC, Mpindi JP, Kilpinen S, Rognum TO, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI. | 10/25/2014 |
| Single-nucleotide polymorphisms in the Regulatory Regions of the VNN1 Gene Are Associated with inflammatory bowel diseases. | Functional polymorphisms in the regulatory regions of the VNN1 gene are associated with susceptibility to inflammatory bowel diseases.
Gensollen T, Bourges C, Rihet P, Rostan A, Millet V, Noguchi T, Bourdon V, Sobol H, Dubuquoy L, Bertin B, Fumery M, Desreumaux P, Colombel JF, Chamaillard M, Hebuterne X, Hofman P, Naquet P, Galland F. | 05/24/2014 |
| Microparticle internalization required the interaction of the ectoenzyme Vanin-1 (VNN1), an abundant surface protein on the microparticles, with lipid raft domains of endothelial cells. | Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells.
Povero D, Eguchi A, Niesman IR, Andronikou N, de Mollerat du Jeu X, Mulya A, Berk M, Lazic M, Thapaliya S, Parola M, Patel HH, Feldstein AE., Free PMC Article | 05/3/2014 |
| It isthe enzyme that recycles pantothenic acid (vitamin B5) generated during coenzyme A breakdown and actively involved in the progression of inflammatory reactions by generating cysteamine. | Linkage between coenzyme a metabolism and inflammation: roles of pantetheinase.
Nitto T, Onodera K. | 04/5/2014 |
| Liver contributes to Vanin-1 secretion in serum and PPARalpha is a limiting factor in serum Vnn1 production. | PPARalpha regulates the production of serum Vanin-1 by liver.
Rommelaere S, Millet V, Gensollen T, Bourges C, Eeckhoute J, Hennuyer N, Baugé E, Chasson L, Cacciatore I, Staels B, Pitari G, Galland F, Naquet P. | 01/11/2014 |
| data do not support a major role for the Vanin 1 T26I variant in determining blood pressure level and incident ischemic events | Vanin-1 T26I polymorphism, hypertension and cardiovascular events in two large urban-based prospective studies in Swedes.
Fava C, Montagnana M, Danese E, Sjögren M, Almgren P, Engström G, Hedblad B, Guidi GC, Minuz P, Melander O. | 07/6/2013 |
| Our data suggest that VNN1 gene expression and the G-137T variant are associated with HDL-C levels in Mexican children, particularly in prepubertal girls. | VNN1 gene expression levels and the G-137T polymorphism are associated with HDL-C levels in Mexican prepubertal children.
Jacobo-Albavera L, Aguayo-de la Rosa PI, Villarreal-Molina T, Villamil-Ramírez H, León-Mimila P, Romero-Hidalgo S, López-Contreras BE, Sánchez-Muñoz F, Bojalil R, González-Barrios JA, Aguilar-Salinas CA, Canizales-Quinteros S., Free PMC Article | 06/1/2013 |
| Urinary vanin-1, an ectoenzyme pantetheinase, distinguished diabetic patients with macroalbuminuria from those with normal albuminuria. | Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy.
Fugmann T, Borgia B, Révész C, Godó M, Forsblom C, Hamar P, Holthöfer H, Neri D, Roesli C. | 11/26/2011 |
| Vanin-1 is a specific and sensitive biomarker for renal tubular injury induced by organic solvents. | Vanin-1: a potential biomarker for nephrotoxicant-induced renal injury.
Hosohata K, Ando H, Fujiwara Y, Fujimura A. | 11/26/2011 |