Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer. | Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer. Rustgi N, Wu S, Samec T, Walker P, Xiu J, Lou E, Goel S, Saeed A, Moy RH., Free PMC Article | 10/22/2024 |
Copy number signatures and CCNE1 amplification reveal the involvement of replication stress in high-grade endometrial tumors oncogenesis. | Copy number signatures and CCNE1 amplification reveal the involvement of replication stress in high-grade endometrial tumors oncogenesis. Marlin R, Loger JS, Joachim C, Ebring C, Robert-Siegwald G, Pennont S, Rose M, Raguette K, Suez-Panama V, Ulric-Gervaise S, Lusbec S, Bera O, Vallard A, Aline-Fardin A, Colomba E, Jean-Laurent M., Free PMC Article | 09/24/2024 |
hsa-miR-CHA2, a novel microRNA, exhibits anticancer effects by suppressing cyclin E1 in human non-small cell lung cancer cells. | hsa-miR-CHA2, a novel microRNA, exhibits anticancer effects by suppressing cyclin E1 in human non-small cell lung cancer cells. Lee SJ, Jeon SH, Cho S, Kim CM, Yoo JK, Oh SH, Kim JH, Yang YD, Kim JK. | 07/1/2024 |
RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells. | RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells. Audrey A, Kok YP, Yu S, de Haan L, van de Kooij B, van den Tempel N, Chen M, de Boer HR, van der Vegt B, van Vugt MATM. | 05/10/2024 |
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression. | PPM1D activity promotes the replication stress caused by cyclin E1 overexpression. Martinikova AS, Stoyanov M, Oravetzova A, Kok YP, Yu S, Dobrovolna J, Janscak P, van Vugt M, Macurek L., Free PMC Article | 01/8/2024 |
LncRNA EILA promotes CDK4/6 inhibitor resistance in breast cancer by stabilizing cyclin E1 protein. | LncRNA EILA promotes CDK4/6 inhibitor resistance in breast cancer by stabilizing cyclin E1 protein. Cai Z, Shi Q, Li Y, Jin L, Li S, Wong LL, Wang J, Jiang X, Zhu M, Lin J, Wang Q, Yang W, Liu Y, Zhang J, Gong C, Yao H, Yao Y, Liu Q., Free PMC Article | 10/10/2023 |
PKMYT1: A Potential Target for CCNE1 Amplificated Colorectal Tumors. | PKMYT1: A Potential Target for CCNE1 Amplificated Colorectal Tumors. Fang Y, Zhang X, Guo Y, Dong Y, Liu W, Hu X, Li X, Gao D. | 09/21/2023 |
Long noncoding RNA LINC02568 sequesters microRNA-874-3p to facilitate malignancy in breast cancer cells via cyclin E1 overexpression. | Long noncoding RNA LINC02568 sequesters microRNA-874-3p to facilitate malignancy in breast cancer cells via cyclin E1 overexpression. Dong YI, Zhang L, Guan X, Liu T, Zhou L., Free PMC Article | 06/21/2023 |
PTEN Deficiency in Tubo-Ovarian High-Grade Serous Carcinoma is Associated with Poor Progression-Free Survival and is Mutually Exclusive with CCNE1 Amplification. | PTEN Deficiency in Tubo-Ovarian High-Grade Serous Carcinoma is Associated with Poor Progression-Free Survival and is Mutually Exclusive with CCNE1 Amplification. Zhang X, Wang A, Han L, Liang B, Allard G, Diver E, Howitt BE. | 05/22/2023 |
N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21[cip1/waf1]/CDK2-Cyclin E1 axis-mediated cell cycle transition. | N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition. Liu R, Miao J, Jia Y, Kong G, Hong F, Li F, Zhai M, Zhang R, Liu J, Xu X, Wang T, Liu H, Hu J, Yang Y, He A., Free PMC Article | 05/19/2023 |
Circular RNA circSEMA5A facilitates colorectal cancer development by regulating microRNA-195-5p to target CCNE1 axis. | Circular RNA circSEMA5A facilitates colorectal cancer development by regulating microRNA-195-5p to target CCNE1 axis. Ye Q, Liu S, Lin S, Xie W. | 05/17/2023 |
CCNE1 is a predictive and immunotherapeutic indicator in various cancers including UCEC: a pan-cancer analysis. | CCNE1 is a predictive and immunotherapeutic indicator in various cancers including UCEC: a pan-cancer analysis. Zheng X, Chen L, Liu W, Zhao S, Yan Y, Zhao J, Tian W, Wang Y., Free PMC Article | 03/29/2023 |
Long Non-coding RNA LINC00473 Promotes Breast Cancer Progression via miR-424-5p/CCNE1 Pathway. | Long Non-coding RNA LINC00473 Promotes Breast Cancer Progression via miR-424-5p/CCNE1 Pathway. Zhang C, Yang T. | 03/14/2023 |
Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication. | Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication. Zeng J, Hills SA, Ozono E, Diffley JFX. | 02/11/2023 |
Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences. | Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences. Yao S, Meric-Bernstam F, Hong D, Janku F, Naing A, Piha-Paul SA, Tsimberidou AM, Karp D, Subbiah V, Yap TA, Ahnert JR, Pant S, Dumbrava EEI, Wathoo C, Campbell E, Yu L, Yamamura Y, Fu S., Free PMC Article | 05/28/2022 |
CCNE1 Promotes Progression and is Associated with Poor Prognosis in Lung Adenocarcinoma. | CCNE1 Promotes Progression and is Associated with Poor Prognosis in Lung Adenocarcinoma. Ma G, Yang L, Dong J, Zhang L. | 05/21/2022 |
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition. | CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition. Gallo D, Young JTF, Fourtounis J, Martino G, Álvarez-Quilón A, Bernier C, Duffy NM, Papp R, Roulston A, Stocco R, Szychowski J, Veloso A, Alam H, Baruah PS, Fortin AB, Bowlan J, Chaudhary N, Desjardins J, Dietrich E, Fournier S, Fugère-Desjardins C, Goullet de Rugy T, Leclaire ME, Liu B, Bhaskaran V, Mamane Y, Melo H, Nicolas O, Singhania A, Szilard RK, Tkáč J, Yin SY, Morris SJ, Zinda M, Marshall CG, Durocher D., Free PMC Article | 05/7/2022 |
Role of Genetic Variations in CDK2, CCNE1 and p27(KIP1) in Prostate Cancer. | Role of Genetic Variations in CDK2, CCNE1 and p27(KIP1) in Prostate Cancer. Híveš M, Jurečeková J, Kliment J, Grendár M, Kaplán P, Dušenka R, Evin D, Vilčková M, Holečková KH, Sivoňová MK., Free PMC Article | 05/7/2022 |
CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models. | CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models. Xu H, George E, Kinose Y, Kim H, Shah JB, Peake JD, Ferman B, Medvedev S, Murtha T, Barger CJ, Devins KM, D'Andrea K, Wubbenhorst B, Schwartz LE, Hwang WT, Mills GB, Nathanson KL, Karpf AR, Drapkin R, Brown EJ, Simpkins F., Free PMC Article | 03/5/2022 |
MYC amplifications are common events in childhood osteosarcoma. | MYC amplifications are common events in childhood osteosarcoma. De Noon S, Ijaz J, Coorens TH, Amary F, Ye H, Strobl A, Lyskjaer I, Flanagan AM, Behjati S., Free PMC Article | 02/19/2022 |
Clinical significance of CCNE1 copy number gain in acral melanoma patients. | Clinical significance of CCNE1 copy number gain in acral melanoma patients. Wu X, Yan J, Yu J, Cheng Z, Guo Q, Kong Y, Guo J. | 01/1/2022 |
Reduced SKP1 and CUL1 expression underlies increases in Cyclin E1 and chromosome instability in cellular precursors of high-grade serous ovarian cancer. | Reduced SKP1 and CUL1 expression underlies increases in Cyclin E1 and chromosome instability in cellular precursors of high-grade serous ovarian cancer. Lepage CC, Palmer MCL, Farrell AC, Neudorf NM, Lichtensztejn Z, Nachtigal MW, McManus KJ., Free PMC Article | 12/18/2021 |
CCNE1 and E2F1 Partially Suppress G1 Phase Arrest Caused by Spliceostatin A Treatment. | CCNE1 and E2F1 Partially Suppress G1 Phase Arrest Caused by Spliceostatin A Treatment. Kikuchi K, Kaida D., Free PMC Article | 12/18/2021 |
Multiple bronchiolar adenomas with malignant transformation and CCNE1 mutation: a case report and literature review. | Multiple bronchiolar adenomas with malignant transformation and CCNE1 mutation: a case report and literature review. Li X, Wu Y, Hui D, Luo X, Wu W, Zhang J, Chen H., Free PMC Article | 10/23/2021 |
Silencing of long noncoding RNA MYLK-AS1 suppresses nephroblastoma via down-regulation of CCNE1 through transcription factor TCF7L2. | Silencing of long noncoding RNA MYLK-AS1 suppresses nephroblastoma via down-regulation of CCNE1 through transcription factor TCF7L2. Zhu S, Zhang J, Gao X, Tang X, Cui Y, Li D, Jia W. | 10/23/2021 |