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    CCNE1 cyclin E1 [ Homo sapiens (human) ]

    Gene ID: 898, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer.

    Molecular Landscape and Clinical Implication of CCNE1-amplified Esophagogastric Cancer.
    Rustgi N, Wu S, Samec T, Walker P, Xiu J, Lou E, Goel S, Saeed A, Moy RH., Free PMC Article

    10/22/2024
    Copy number signatures and CCNE1 amplification reveal the involvement of replication stress in high-grade endometrial tumors oncogenesis.

    Copy number signatures and CCNE1 amplification reveal the involvement of replication stress in high-grade endometrial tumors oncogenesis.
    Marlin R, Loger JS, Joachim C, Ebring C, Robert-Siegwald G, Pennont S, Rose M, Raguette K, Suez-Panama V, Ulric-Gervaise S, Lusbec S, Bera O, Vallard A, Aline-Fardin A, Colomba E, Jean-Laurent M., Free PMC Article

    09/24/2024
    hsa-miR-CHA2, a novel microRNA, exhibits anticancer effects by suppressing cyclin E1 in human non-small cell lung cancer cells.

    hsa-miR-CHA2, a novel microRNA, exhibits anticancer effects by suppressing cyclin E1 in human non-small cell lung cancer cells.
    Lee SJ, Jeon SH, Cho S, Kim CM, Yoo JK, Oh SH, Kim JH, Yang YD, Kim JK.

    07/1/2024
    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells.

    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells.
    Audrey A, Kok YP, Yu S, de Haan L, van de Kooij B, van den Tempel N, Chen M, de Boer HR, van der Vegt B, van Vugt MATM.

    05/10/2024
    PPM1D activity promotes the replication stress caused by cyclin E1 overexpression.

    PPM1D activity promotes the replication stress caused by cyclin E1 overexpression.
    Martinikova AS, Stoyanov M, Oravetzova A, Kok YP, Yu S, Dobrovolna J, Janscak P, van Vugt M, Macurek L., Free PMC Article

    01/8/2024
    LncRNA EILA promotes CDK4/6 inhibitor resistance in breast cancer by stabilizing cyclin E1 protein.

    LncRNA EILA promotes CDK4/6 inhibitor resistance in breast cancer by stabilizing cyclin E1 protein.
    Cai Z, Shi Q, Li Y, Jin L, Li S, Wong LL, Wang J, Jiang X, Zhu M, Lin J, Wang Q, Yang W, Liu Y, Zhang J, Gong C, Yao H, Yao Y, Liu Q., Free PMC Article

    10/10/2023
    PKMYT1: A Potential Target for CCNE1 Amplificated Colorectal Tumors.

    PKMYT1: A Potential Target for CCNE1 Amplificated Colorectal Tumors.
    Fang Y, Zhang X, Guo Y, Dong Y, Liu W, Hu X, Li X, Gao D.

    09/21/2023
    Long noncoding RNA LINC02568 sequesters microRNA-874-3p to facilitate malignancy in breast cancer cells via cyclin E1 overexpression.

    Long noncoding RNA LINC02568 sequesters microRNA-874-3p to facilitate malignancy in breast cancer cells via cyclin E1 overexpression.
    Dong YI, Zhang L, Guan X, Liu T, Zhou L., Free PMC Article

    06/21/2023
    PTEN Deficiency in Tubo-Ovarian High-Grade Serous Carcinoma is Associated with Poor Progression-Free Survival and is Mutually Exclusive with CCNE1 Amplification.

    PTEN Deficiency in Tubo-Ovarian High-Grade Serous Carcinoma is Associated with Poor Progression-Free Survival and is Mutually Exclusive with CCNE1 Amplification.
    Zhang X, Wang A, Han L, Liang B, Allard G, Diver E, Howitt BE.

    05/22/2023
    N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21[cip1/waf1]/CDK2-Cyclin E1 axis-mediated cell cycle transition.

    N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21(cip1/waf1)/CDK2-Cyclin E1 axis-mediated cell cycle transition.
    Liu R, Miao J, Jia Y, Kong G, Hong F, Li F, Zhai M, Zhang R, Liu J, Xu X, Wang T, Liu H, Hu J, Yang Y, He A., Free PMC Article

    05/19/2023
    Circular RNA circSEMA5A facilitates colorectal cancer development by regulating microRNA-195-5p to target CCNE1 axis.

    Circular RNA circSEMA5A facilitates colorectal cancer development by regulating microRNA-195-5p to target CCNE1 axis.
    Ye Q, Liu S, Lin S, Xie W.

    05/17/2023
    CCNE1 is a predictive and immunotherapeutic indicator in various cancers including UCEC: a pan-cancer analysis.

    CCNE1 is a predictive and immunotherapeutic indicator in various cancers including UCEC: a pan-cancer analysis.
    Zheng X, Chen L, Liu W, Zhao S, Yan Y, Zhao J, Tian W, Wang Y., Free PMC Article

    03/29/2023
    Long Non-coding RNA LINC00473 Promotes Breast Cancer Progression via miR-424-5p/CCNE1 Pathway.

    Long Non-coding RNA LINC00473 Promotes Breast Cancer Progression via miR-424-5p/CCNE1 Pathway.
    Zhang C, Yang T.

    03/14/2023
    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication.

    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication.
    Zeng J, Hills SA, Ozono E, Diffley JFX.

    02/11/2023
    Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences.

    Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences.
    Yao S, Meric-Bernstam F, Hong D, Janku F, Naing A, Piha-Paul SA, Tsimberidou AM, Karp D, Subbiah V, Yap TA, Ahnert JR, Pant S, Dumbrava EEI, Wathoo C, Campbell E, Yu L, Yamamura Y, Fu S., Free PMC Article

    05/28/2022
    CCNE1 Promotes Progression and is Associated with Poor Prognosis in Lung Adenocarcinoma.

    CCNE1 Promotes Progression and is Associated with Poor Prognosis in Lung Adenocarcinoma.
    Ma G, Yang L, Dong J, Zhang L.

    05/21/2022
    CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.

    CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
    Gallo D, Young JTF, Fourtounis J, Martino G, Álvarez-Quilón A, Bernier C, Duffy NM, Papp R, Roulston A, Stocco R, Szychowski J, Veloso A, Alam H, Baruah PS, Fortin AB, Bowlan J, Chaudhary N, Desjardins J, Dietrich E, Fournier S, Fugère-Desjardins C, Goullet de Rugy T, Leclaire ME, Liu B, Bhaskaran V, Mamane Y, Melo H, Nicolas O, Singhania A, Szilard RK, Tkáč J, Yin SY, Morris SJ, Zinda M, Marshall CG, Durocher D., Free PMC Article

    05/7/2022
    Role of Genetic Variations in CDK2, CCNE1 and p27(KIP1) in Prostate Cancer.

    Role of Genetic Variations in CDK2, CCNE1 and p27(KIP1) in Prostate Cancer.
    Híveš M, Jurečeková J, Kliment J, Grendár M, Kaplán P, Dušenka R, Evin D, Vilčková M, Holečková KH, Sivoňová MK., Free PMC Article

    05/7/2022
    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models.

    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models.
    Xu H, George E, Kinose Y, Kim H, Shah JB, Peake JD, Ferman B, Medvedev S, Murtha T, Barger CJ, Devins KM, D'Andrea K, Wubbenhorst B, Schwartz LE, Hwang WT, Mills GB, Nathanson KL, Karpf AR, Drapkin R, Brown EJ, Simpkins F., Free PMC Article

    03/5/2022
    MYC amplifications are common events in childhood osteosarcoma.

    MYC amplifications are common events in childhood osteosarcoma.
    De Noon S, Ijaz J, Coorens TH, Amary F, Ye H, Strobl A, Lyskjaer I, Flanagan AM, Behjati S., Free PMC Article

    02/19/2022
    Clinical significance of CCNE1 copy number gain in acral melanoma patients.

    Clinical significance of CCNE1 copy number gain in acral melanoma patients.
    Wu X, Yan J, Yu J, Cheng Z, Guo Q, Kong Y, Guo J.

    01/1/2022
    Reduced SKP1 and CUL1 expression underlies increases in Cyclin E1 and chromosome instability in cellular precursors of high-grade serous ovarian cancer.

    Reduced SKP1 and CUL1 expression underlies increases in Cyclin E1 and chromosome instability in cellular precursors of high-grade serous ovarian cancer.
    Lepage CC, Palmer MCL, Farrell AC, Neudorf NM, Lichtensztejn Z, Nachtigal MW, McManus KJ., Free PMC Article

    12/18/2021
    CCNE1 and E2F1 Partially Suppress G1 Phase Arrest Caused by Spliceostatin A Treatment.

    CCNE1 and E2F1 Partially Suppress G1 Phase Arrest Caused by Spliceostatin A Treatment.
    Kikuchi K, Kaida D., Free PMC Article

    12/18/2021
    Multiple bronchiolar adenomas with malignant transformation and CCNE1 mutation: a case report and literature review.

    Multiple bronchiolar adenomas with malignant transformation and CCNE1 mutation: a case report and literature review.
    Li X, Wu Y, Hui D, Luo X, Wu W, Zhang J, Chen H., Free PMC Article

    10/23/2021
    Silencing of long noncoding RNA MYLK-AS1 suppresses nephroblastoma via down-regulation of CCNE1 through transcription factor TCF7L2.

    Silencing of long noncoding RNA MYLK-AS1 suppresses nephroblastoma via down-regulation of CCNE1 through transcription factor TCF7L2.
    Zhu S, Zhang J, Gao X, Tang X, Cui Y, Li D, Jia W.

    10/23/2021
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