Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. | Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. Ciapponi M, Karlukova E, Schkölziger S, Benda C, Müller J., Free PMC Article | 08/8/2024 |
Protein regulator of cytokinesis 1: a potential oncogenic driver. | Protein regulator of cytokinesis 1: a potential oncogenic driver. Li S, Motiño O, Lambertucci F, Martins I, Sun L, Kroemer G., Free PMC Article | 11/22/2023 |
Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis. | Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis. Gluszek-Kustusz A, Craske B, Legal T, McHugh T, Welburn JP., Free PMC Article | 11/7/2023 |
Genetic associations of TMEM154, PRC1 and ZFAND6 loci with type 2 diabetes in an endogamous business community of North India. | Genetic associations of TMEM154, PRC1 and ZFAND6 loci with type 2 diabetes in an endogamous business community of North India. Walia GK, Sharma P, Agarwal T, Lal M, Negandhi H, Prabhakaran D, Khadgawat R, Sachdeva MP, Gupta V., Free PMC Article | 09/25/2023 |
CircKDM1B promotes hepatocellular carcinoma progression through regulating miR-1322/PRC1 axis. | CircKDM1B promotes hepatocellular carcinoma progression through regulating miR-1322/PRC1 axis. Yi M, Lv S, He Y, Wu Y, Zhang J, Chen Q. | 07/10/2023 |
Expression of the cytokinesis regulator PRC1 results in p53-pathway activation in A549 cells but does not directly regulate gene expression in the nucleus. | Expression of the cytokinesis regulator PRC1 results in p53-pathway activation in A549 cells but does not directly regulate gene expression in the nucleus. Hanselmann S, Gertzmann D, Shin WJ, Ade CP, Gaubatz S., Free PMC Article | 01/28/2023 |
PRC1 plays an important role in lung adenocarcinoma and is potentially targeted by fostamatinib. | PRC1 plays an important role in lung adenocarcinoma and is potentially targeted by fostamatinib. Zhu P, Cui N, Song ZY, Yong WX, Luo XX, Wang GC, Wang X, Wu YN, Xu Q, Zhang LM, Hao GX, Liu Y, Zhang ZM. | 12/31/2022 |
Protein Regulator of Cytokinesis 1 (PRC1) Upregulation Promotes Immune Suppression in Liver Hepatocellular Carcinoma. | Protein Regulator of Cytokinesis 1 (PRC1) Upregulation Promotes Immune Suppression in Liver Hepatocellular Carcinoma. Zhang C, Xu H, Sui X, Wu T, Chen B, Wang S, Wang X., Free PMC Article | 08/27/2022 |
Two modes of PRC1-mediated mechanical resistance to kinesin-driven microtubule network disruption. | Two modes of PRC1-mediated mechanical resistance to kinesin-driven microtubule network disruption. Alfieri A, Gaska I, Forth S. | 02/19/2022 |
Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces. | Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces. Jagrić M, Risteski P, Martinčić J, Milas A, Tolić IM., Free PMC Article | 02/5/2022 |
TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis. | TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis. Uribe ML, Dahlhoff M, Batra RN, Nataraj NB, Haga Y, Drago-Garcia D, Marrocco I, Sekar A, Ghosh S, Vaknin I, Lebon S, Kramarski L, Tsutsumi Y, Choi I, Rueda OM, Caldas C, Yarden Y., Free PMC Article | 01/22/2022 |
MicroRNA-194 inhibits PRC1 activation of the Wnt/beta-catenin signaling pathway to prevent tumorigenesis by elevating self-renewal of non-side population cells and side population cells in esophageal cancer stem cells. | MicroRNA-194 inhibits PRC1 activation of the Wnt/β-catenin signaling pathway to prevent tumorigenesis by elevating self-renewal of non-side population cells and side population cells in esophageal cancer stem cells. Cai S, Weng Y, Miao F. | 11/27/2021 |
CENPE, PRC1, TTK, and PLK4 May Play Crucial Roles in the Osteosarcoma Progression. | CENPE, PRC1, TTK, and PLK4 May Play Crucial Roles in the Osteosarcoma Progression. Wang F, Zhao Q, Liu W, Kong D., Free PMC Article | 11/27/2021 |
Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction. | Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction. Eeftens JM, Kapoor M, Michieletto D, Brangwynne CP., Free PMC Article | 11/6/2021 |
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer. | Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer. Li J, Ohmura S, Marchetto A, Orth MF, Imle R, Dallmayer M, Musa J, Knott MML, Hölting TLB, Stein S, Funk CM, Sastre A, Alonso J, Bestvater F, Kasan M, Romero-Pérez L, Hartmann W, Ranft A, Banito A, Dirksen U, Kirchner T, Cidre-Aranaz F, Grünewald TGP., Free PMC Article | 10/23/2021 |
AKT-mediated regulation of chromatin ubiquitylation and tumorigenesis through Mel18 phosphorylation. | AKT-mediated regulation of chromatin ubiquitylation and tumorigenesis through Mel18 phosphorylation. Mai J, Peng XD, Tang J, Du T, Chen YH, Wang ZF, Zhang HL, Huang JH, Zhong ZY, Yang D, Li ZL, Huang Y, Feng GK, Zhu XF, Deng R. | 10/23/2021 |
Src-mediated tyrosine phosphorylation of PRC1 and kinastrin/SKAP on the mitotic spindle. | Src-mediated tyrosine phosphorylation of PRC1 and kinastrin/SKAP on the mitotic spindle. Morii M, Kubota S, Hasegawa C, Takeda Y, Kometani S, Enomoto K, Suzuki T, Yanase S, Sato R, Akatsu A, Hirata K, Honda T, Kuga T, Tomonaga T, Nakayama Y, Yamaguchi N, Yamaguchi N., Free PMC Article | 10/2/2021 |
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation. | Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation. Vukušić K, Ponjavić I, Buđa R, Risteski P, Tolić IM., Free PMC Article | 09/25/2021 |
Differential regulation of single microtubules and bundles by a three-protein module. | Differential regulation of single microtubules and bundles by a three-protein module. Mani N, Jiang S, Neary AE, Wijeratne SS, Subramanian R., Free PMC Article | 09/11/2021 |
Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly. | Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly. Liu X, Xu L, Li J, Yao PY, Wang W, Ismail H, Wang H, Liao B, Yang Z, Ward T, Ruan K, Zhang J, Wu Q, He P, Ding X, Wang D, Fu C, Dou Z, Yan F, Wang W, Liu X, Yao X., Free PMC Article | 08/28/2021 |
Independent domains for recruitment of PRC1 and PRC2 by human XIST. | Independent domains for recruitment of PRC1 and PRC2 by human XIST. Dixon-McDougall T, Brown CJ., Free PMC Article | 08/7/2021 |
Analysis of transcriptome in the relationship between expression of PRC1 protein and prognosis of patients with cholangiocarcinoma. | Analysis of transcriptome in the relationship between expression of PRC1 protein and prognosis of patients with cholangiocarcinoma. Wang Q, Lu S, Chen Y, He H, Lu W, Lin K., Free PMC Article | 06/26/2021 |
RNA interference-mediated knockdown of the Drosophila ortholog or PRC1 in insulin-producing cells, a model for mammalian beta cells, conferred increased insulin output. | Discovering human diabetes-risk gene function with genetics and physiological assays. Peiris H, Park S, Louis S, Gu X, Lam JY, Asplund O, Ippolito GC, Bottino R, Groop L, Tucker H, Kim SK., Free PMC Article | 06/14/2021 |
The roles of Polycomb repressive complexes in mammalian development and cancer. | The roles of Polycomb repressive complexes in mammalian development and cancer. Piunti A, Shilatifard A. | 05/8/2021 |
CBF-1 Promotes the Establishment and Maintenance of HIV Latency by Recruiting Polycomb Repressive Complexes, PRC1 and PRC2, at HIV LTR. | CBF-1 Promotes the Establishment and Maintenance of HIV Latency by Recruiting Polycomb Repressive Complexes, PRC1 and PRC2, at HIV LTR. Sharma AL, Hokello J, Sonti S, Zicari S, Sun L, Alqatawni A, Bukrinsky M, Simon G, Chauhan A, Daniel R, Tyagi M., Free PMC Article | 03/6/2021 |