| Pharmacological Activity of Matrine in Inhibiting Colon Cancer Cells VM Formation, Proliferation, and Invasion by Downregulating Claudin-9 Mediated EMT Process and MAPK Signaling Pathway. | Pharmacological Activity of Matrine in Inhibiting Colon Cancer Cells VM Formation, Proliferation, and Invasion by Downregulating Claudin-9 Mediated EMT Process and MAPK Signaling Pathway.
Du Q, Lin Y, Ding C, Wu L, Xu Y, Feng Q., Free PMC Article | 09/28/2023 |
| Claudin9 is a novel prognostic biomarker for endometrial cancer. | Claudin‑9 is a novel prognostic biomarker for endometrial cancer.
Endo Y, Sugimoto K, Kobayashi M, Kobayashi Y, Kojima M, Furukawa S, Soeda S, Watanabe T, Higashi AY, Higashi T, Hashimoto Y, Fujimori K, Chiba H., Free PMC Article | 09/24/2022 |
| We conclude that CLDN9 is essential for proper audition in humans and its disruption leads to SNHL in humans. | A truncating CLDN9 variant is associated with autosomal recessive nonsyndromic hearing loss.
Sineni CJ, Yildirim-Baylan M, Guo S, Camarena V, Wang G, Tokgoz-Yilmaz S, Duman D, Bademci G, Tekin M., Free PMC Article | 10/5/2019 |
| these results suggest that Helicobacter pylori lipopolysaccharide induces TLR2 expression in the gastric adenocarcinoma cells, and that the longer the exposure to lipopolysaccharide, the greater the expression of TLR2 in the cell membrane; consequently the expression of claudin-4, -6, -7 and -9 also increases | TLR2 activation induced by H. pylori LPS promotes the differential expression of claudin-4, -6, -7 and -9 via either STAT3 and ERK1/2 in AGS cells.
Chavarría-Velázquez CO, Torres-Martínez AC, Montaño LF, Rendón-Huerta EP. | 07/28/2018 |
| the expression of claudin-5 and claudin-9 was down-regulated while the expression of claudin-8 was up-regulated in cervical carcinoma tissues compared with adjacent non-neoplastic tissues. | Expression of claudin-5, -7, -8 and -9 in cervical carcinoma tissues and adjacent non-neoplastic tissues.
Zhu J, Wang R, Cao H, Zhang H, Xu S, Wang A, Liu B, Wang Y, Wang R., Free PMC Article | 08/20/2016 |
| CLDN9 may be an important biomarker for invasive pituitary oncocytomas. | Overexpression of the cell adhesion molecule claudin-9 is associated with invasion in pituitary oncocytomas.
Hong L, Wu Y, Feng J, Yu S, Li C, Wu Y, Li Z, Cao L, Wang F, Zhang Y. | 02/14/2015 |
| Although claudin-6 and claudin-9 can serve as entry factors in cell lines, hepatitis C virus infection into human hepatocytes is not dependent on claudin-6 and claudin-9. | Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies.
Fofana I, Zona L, Thumann C, Heydmann L, Durand SC, Lupberger J, Blum HE, Pessaux P, Gondeau C, Reynolds GM, McKeating JA, Grunert F, Thompson J, Zeisel MB, Baumert TF., Free PMC Article | 11/16/2013 |
| Increased expression of claudin-6, claudin-7, or claudin-9 is sufficient to enhance tumorigenic properties of a gastric adenocarcinoma cell line. | Claudin-6, 7, or 9 overexpression in the human gastric adenocarcinoma cell line AGS increases its invasiveness, migration, and proliferation rate.
Zavala-Zendejas VE, Torres-Martinez AC, Salas-Morales B, Fortoul TI, Montaño LF, Rendon-Huerta EP. | 01/15/2011 |
| Claudins 6, 7, and 9 expressions are closely related to gastric carcinogenesis. | Distribution and expression pattern of claudins 6, 7, and 9 in diffuse- and intestinal-type gastric adenocarcinomas.
Rendón-Huerta E, Teresa F, Teresa GM, Xochitl GS, Georgina AF, Veronica ZZ, Montaño LF. | 06/28/2010 |
| Mouse studies suggest that claudin-9 deficiency may cause hearing loss not only in mice but also in humans. | A claudin-9-based ion permeability barrier is essential for hearing.
Nakano Y, Kim SH, Kim HM, Sanneman JD, Zhang Y, Smith RJ, Marcus DC, Wangemann P, Nessler RA, Bánfi B., Free PMC Article | 06/1/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.
Hosgood HD 3rd, Zhang L, Shen M, Berndt SI, Vermeulen R, Li G, Yin S, Yeager M, Yuenger J, Rothman N, Chanock S, Smith M, Lan Q., Free PMC Article | 06/1/2010 |
| claudin-6 and claudin-9 expressed in CD81+ cells also enable the entry of HCV pseudoparticles derived from six of the major genotypes. | The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus.
Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T., Free PMC Article | 01/21/2010 |
| Residues N38 and V45 in the first extracellular loop (EL1) of CLDN9 are necessary for HCV entry. | Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus.
Zheng A, Yuan F, Li Y, Zhu F, Hou P, Li J, Song X, Ding M, Deng H., Free PMC Article | 01/21/2010 |
| CLDN9, clustered with CLDN6 at human chromosome 16p13.3, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. | CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family.
Katoh M, Katoh M. | 12/2/2003 |