| Screening Differential CircRNAs Expression Profiles Reveals the Regulatory Role of the has_circTPT1_003-has-miR-218-5p-CCNE2/SMC4 Signaling Axis in Bladder Carcinoma Progression. | Screening Differential CircRNAs Expression Profiles Reveals the Regulatory Role of the has_circTPT1_003-has-miR-218-5p-CCNE2/SMC4 Signaling Axis in Bladder Carcinoma Progression.
Wang J, Shao J, Lu Y, Su W, Dong H, Wang P, Lin Z, Feng J, Wang D, Zhao H, Tan J. | 07/26/2024 |
| Downregulation of miR-503-5p Promotes the Development of Pancreatic Cancer by Targeting Cyclin E2. | Downregulation of miR-503-5p Promotes the Development of Pancreatic Cancer by Targeting Cyclin E2.
Li F, Ling YP, Wang P, Gu SS, Jiang H, Zhu J. | 03/21/2024 |
| Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve. | Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve.
Chignon A, Argaud D, Boulanger MC, Mkannez G, Bon-Baret V, Li Z, Thériault S, Bossé Y, Mathieu P., Free PMC Article | 02/19/2022 |
| E2F transcription factor 1 (E2F1) promotes the transforming growth factor TGF-beta1 induced human cardiac fibroblasts differentiation through promoting the transcription of CCNE2 gene. | E2F transcription factor 1 (E2F1) promotes the transforming growth factor TGF-β1 induced human cardiac fibroblasts differentiation through promoting the transcription of CCNE2 gene.
Liao R, Xie B, Cui J, Qi Z, Xue S, Wang Y., Free PMC Article | 01/1/2022 |
| Vascular endothelial cell-derived exosomal miR-30a-5p inhibits lung adenocarcinoma malignant progression by targeting CCNE2. | Vascular endothelial cell-derived exosomal miR-30a-5p inhibits lung adenocarcinoma malignant progression by targeting CCNE2.
Tao K, Liu J, Liang J, Xu X, Xu L, Mao W. | 12/25/2021 |
| SP1-induced overexpression of LINC00520 facilitates non-small cell lung cancer progression through miR-577/CCNE2 pathway and predicts poor prognosis. | SP1-induced overexpression of LINC00520 facilitates non-small cell lung cancer progression through miR-577/CCNE2 pathway and predicts poor prognosis.
Wang JF, Xi ZN, Su HJ, Bao Z, Qiao YH. | 10/9/2021 |
| Clinical significance of CCNE2 protein and mRNA expression in thyroid cancer tissues. | Clinical significance of CCNE2 protein and mRNA expression in thyroid cancer tissues.
Liu CZ, Guo WP, Peng JB, Chen G, Lin P, Huang XL, Liu XF, Yang H, He Y, Pang YY, Ma W. | 09/4/2021 |
| Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down-regulating CCNE2 in pancreatic ductal adenocarcinoma. | Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down-regulating CCNE2 in pancreatic ductal adenocarcinoma.
Yang J, Dong Z, Ren A, Fu G, Zhang K, Li C, Wang X, Cui H., Free PMC Article | 05/1/2021 |
| CARM1 promotes non-small cell lung cancer progression through upregulating CCNE2 expression. | CARM1 promotes non-small cell lung cancer progression through upregulating CCNE2 expression.
Wu D, He J, Zhang W, Wang K, Jin S, Li J, Gao W., Free PMC Article | 03/13/2021 |
| Nicotine-upregulated miR-30a arrests cell cycle in G1 phase by directly targeting CCNE2 in human periodontal ligament cells. | Nicotine-upregulated miR-30a arrests cell cycle in G1 phase by directly targeting CCNE2 in human periodontal ligament cells.
Wu L, Yang K, Gui Y, Wang X. | 02/27/2021 |
| Circular RNA CircCCNB1 sponges micro RNA-449a to inhibit cellular senescence by targeting CCNE2. | Circular RNA CircCCNB1 sponges micro RNA-449a to inhibit cellular senescence by targeting CCNE2.
Yu AQ, Wang ZX, Wu W, Chen KY, Yan SR, Mao ZB., Free PMC Article | 10/3/2020 |
| The overexpression of MNX1 promoted cervical cancer cells proliferation, migration, and invasion. Moreover, MNX1 upregulated 2 critical cell cycle regulators, CCNE1 and CCNE2. | Motor Neuron and Pancreas Homeobox 1 (MNX1) Is Involved in Promoting Squamous Cervical Cancer Proliferation via Regulating Cyclin E.
Xiao L, Hong L, Zheng W., Free PMC Article | 03/7/2020 |
| Up-regulation of cyclin E2 was observed in gastric cancer tissues.Cyclin E2 was a target of miR-383 in gastric cancer cells. | miR-383 Inhibited the Cell Cycle Progression of Gastric Cancer Cells via Targeting Cyclin E2.
Zhu C, Huang Q, Zhu H. | 08/24/2019 |
| cyclin E2 participates in regulating viral replication through the CDK2/SAMHD1 phosphorylation pathway in an HBV infection system. | Cyclin E2-CDK2 mediates SAMHD1 phosphorylation to abrogate its restriction of HBV replication in hepatoma cells.
Hu J, Qiao M, Chen Y, Tang H, Zhang W, Tang D, Pi S, Dai J, Tang N, Huang A, Hu Y. | 04/13/2019 |
| Cyclin A2 or E1 alterations define a homogenous entity of aggressive hepatocellular carcinoma (HCC) subgroup. | Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress.
Bayard Q, Meunier L, Peneau C, Renault V, Shinde J, Nault JC, Mami I, Couchy G, Amaddeo G, Tubacher E, Bacq D, Meyer V, La Bella T, Debaillon-Vesque A, Bioulac-Sage P, Seror O, Blanc JF, Calderaro J, Deleuze JF, Imbeaud S, Zucman-Rossi J, Letouzé E., Free PMC Article | 01/5/2019 |
| the molecular mechanism of trastuzumab action in BT474 cell line may be regulated by miR-26a and miR-30b and CCNE2 overexpression might play an important role in acquired trastuzumab resistance in HER2+ breast cancer. | The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene.
Tormo E, Adam-Artigues A, Ballester S, Pineda B, Zazo S, González-Alonso P, Albanell J, Rovira A, Rojo F, Lluch A, Eroles P., Free PMC Article | 10/27/2018 |
| Knockdown of CCNE2 promoted MCF7 cell apoptosis and G2-stage cell cycle arrest. | The Dysregulated Expression of KCNQ1OT1 and Its Interaction with Downstream Factors miR-145/CCNE2 in Breast Cancer Cells.
Feng W, Wang C, Liang C, Yang H, Chen D, Yu X, Zhao W, Geng D, Li S, Chen Z, Sun M. | 09/22/2018 |
| Combinatorial PX-866 and Raloxifene Decrease Rb Phosphorylation, Cyclin E2 Transcription, and Proliferation of MCF-7 Breast Cancer Cells | Combinatorial PX-866 and Raloxifene Decrease Rb Phosphorylation, Cyclin E2 Transcription, and Proliferation of MCF-7 Breast Cancer Cells.
Peek GW, Tollefsbol TO., Free PMC Article | 09/16/2017 |
| The results suggest that miR30a may function as a novel tumor suppressor in CRPC. Its antioncogenic activity may occur by the reduced expression of a distinct cell cycle protein, CCNE2. | miRNA-30a functions as a tumor suppressor by downregulating cyclin E2 expression in castration-resistant prostate cancer.
Zhang L, Zhang XW, Liu CH, Lu K, Huang YQ, Wang YD, Xing L, Zhang LJ, Liu N, Jiang H, Sun C, Yang Y, Chen SQ, Chen M, Xu B. | 04/8/2017 |
| Overexpression of cyclin E2 is an early event in gastric carcinogenesis. | Cyclin D1 and cyclin E2 are differentially expressed in gastric cancer.
Kumari S, Puneet, Prasad SB, Yadav SS, Kumar M, Khanna A, Dixit VK, Nath G, Singh S, Narayan G. | 12/31/2016 |
| Survivin and cyclin E2 genes expression may have clinical relevance and can be considered as molecular risk factors for AL. Also they may be useful as predictive markers for treatment outcome in leukemic patients. | Survivin and cyclin E2 genes expression in a cohort of Egyptian acute leukemia patients: Clinical importance and future prospects.
Makhlouf MM. | 11/5/2016 |
| miR-26a regulated mouse hepatocyte proliferation by directly targeting the 3' untranslated regions of cyclin D2/cyclin E2. | miR-26a regulates mouse hepatocyte proliferation via directly targeting the 3' untranslated region of CCND2 and CCNE2.
Zhou J, Ju WQ, Yuan XP, Zhu XF, Wang DP, He XS. | 10/29/2016 |
| In breast cancer patients, high levels of HMGA1 and CCNE2 expression are associated with the YAP/TAZ signature. | A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness.
Pegoraro S, Ros G, Ciani Y, Sgarra R, Piazza S, Manfioletti G., Free PMC Article | 07/2/2016 |
| data suggests the potential role of monomorphic morphology, high cyclin E2 and Ki67 expression as adverse prognostic factors for TNKLPD | Prognostic implication of morphology, cyclinE2 and proliferation in EBV-associated T/NK lymphoproliferative disease in non-immunocompromised hosts.
Ng SB, Ohshima K, Selvarajan V, Huang G, Choo SN, Miyoshi H, Wang S, Chua HC, Yeoh AE, Quah TC, Koh LP, Tan PL, Chng WJ., Free PMC Article | 02/13/2016 |
| miR-144-5p functions as tumour suppressor in BC cells. CCNE1 and CCNE2 were directly regulated by miR-144-5p and might be good prognostic markers for survival of bladder cancer patients | Tumour-suppressive microRNA-144-5p directly targets CCNE1/2 as potential prognostic markers in bladder cancer.
Matsushita R, Seki N, Chiyomaru T, Inoguchi S, Ishihara T, Goto Y, Nishikawa R, Mataki H, Tatarano S, Itesako T, Nakagawa M, Enokida H., Free PMC Article | 10/3/2015 |