Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation. | Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation. Speer NO, Braun RJ, Reynolds EG, Brudnicka A, Swanson JMJ, Henne WM., Free PMC Article | 10/30/2023 |
Completion of mitochondrial division requires the intermembrane space protein Mdi1/Atg44. | Completion of mitochondrial division requires the intermembrane space protein Mdi1/Atg44. Connor OM, Matta SK, Friedman JR., Free PMC Article | 08/7/2023 |
Migrating bubble synthesis promotes mutagenesis through lesions in its template. | Migrating bubble synthesis promotes mutagenesis through lesions in its template. Osia B, Twarowski J, Jackson T, Lobachev K, Liu L, Malkova A., Free PMC Article | 12/17/2022 |
Multi-step recognition of potential 5' splice sites by the Saccharomyces cerevisiae U1 snRNP. | Multi-step recognition of potential 5' splice sites by the Saccharomyces cerevisiae U1 snRNP. Hansen SR, White DS, Scalf M, Corrêa IR, Smith LM, Hoskins AA., Free PMC Article | 09/24/2022 |
The RNA-binding protein Puf5 and the HMGB protein Ixr1 contribute to cell cycle progression through the regulation of cell cycle-specific expression of CLB1 in Saccharomyces cerevisiae. | The RNA-binding protein Puf5 and the HMGB protein Ixr1 contribute to cell cycle progression through the regulation of cell cycle-specific expression of CLB1 in Saccharomyces cerevisiae. Sato M, Irie K, Suda Y, Mizuno T, Irie K., Free PMC Article | 08/27/2022 |
ASNS disruption shortens CTPS cytoophidia in Saccharomyces cerevisiae. | ASNS disruption shortens CTPS cytoophidia in Saccharomyces cerevisiae. Zhang S, Feng HC, Liu JL., Free PMC Article | 07/17/2021 |
Pseudouridine-mediated translation control of mRNA by methionine aminoacyl tRNA synthetase. | Pseudouridine-mediated translation control of mRNA by methionine aminoacyl tRNA synthetase. Levi O, Arava YS., Free PMC Article | 01/23/2021 |
The Phosphatase PP1 Promotes Mitotic Slippage through Mad3 Dephosphorylation. | The Phosphatase PP1 Promotes Mitotic Slippage through Mad3 Dephosphorylation. Ruggiero A, Katou Y, Shirahige K, Séveno M, Piatti S. | 12/5/2020 |
A regulatory circuit between lncRNA and TOR directs amino acid uptake in yeast. | A regulatory circuit between lncRNA and TOR directs amino acid uptake in yeast. Awasthi A, Nain V, Srikanth CV, Puria R. | 08/13/2020 |
The authors propose that Vrl1 regulate autophagy in a similar way as Vps9, and the level of Vrl1 partly decreases through both autophagy-dependent and -independent routes. [Vrl1] | Vrl1 relies on its VPS9-domain to play a role in autophagy in Saccharomyces cerevisiae. Li W, Wu Z, Liang Y. | 12/7/2019 |
MAL62 and TPS1 overexpression in the NTH1 deletion background further strengthened freezing tolerance and improved leavening ability.[MAL62] | MAL62 Overexpression Enhances Freezing Tolerance of Baker's Yeast in Lean Dough by Enhancing Tps1 Activity and Maltose Metabolism. Sun X, Zhang J, Fan ZH, Xiao P, Liu SN, Li RP, Zhu WB, Huang L. | 08/31/2019 |
Npa1p and Dbp6p function in the formation and/or clustering of root helices of large subunit rRNAs which creates the core of the large ribosomal subunit RNA structure. Npa1p also crosslinks to snoRNAs involved in decoding center and peptidyl transferase center modifications and in the immediate vicinity of the binding sites of these snoRNAs on 25S rRNA. [Npa1p] | The Npa1p complex chaperones the assembly of the earliest eukaryotic large ribosomal subunit precursor. Joret C, Capeyrou R, Belhabich-Baumas K, Plisson-Chastang C, Ghandour R, Humbert O, Fribourg S, Leulliot N, Lebaron S, Henras AK, Henry Y., Free PMC Article | 01/19/2019 |
Ydl121c (Exp1) is an ER protein that binds Pma1, is packaged into COPII vesicles, and whose deletion causes ER retention of Pma1. | Two novel effectors of trafficking and maturation of the yeast plasma membrane H(+) -ATPase. Geva Y, Crissman J, Arakel EC, Gómez-Navarro N, Chuartzman SG, Stahmer KR, Schwappach B, Miller EA, Schuldiner M., Free PMC Article | 06/16/2018 |
Report structural basis for noncanonical substrate recognition of cofilin-1/LIMK1 to regulation actin cytoskeleton dynamics. | Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases. Hamill S, Lou HJ, Turk BE, Boggon TJ., Free PMC Article | 08/5/2017 |
Smt1p: Smt1p is likely to be involved in regulation of mitochondrial translation of the ATP8/ATP6. The mechanism of this regulatory pathway is proposed to entail a displacement of the repressor from the translationally mute Smt1-ATP8/ATP6 complex by F1, thereby permitting the Atp22p activator to interact with and promote translation of the mRNA. | Regulation of mitochondrial translation of the ATP8/ATP6 mRNA by Smt1p. Rak M, Su CH, Xu JT, Azpiroz R, Singh AM, Tzagoloff A., Free PMC Article | 01/14/2017 |
These results demonstrate an autoregulatory mechanism that fine-tunes the expression of the Rpl22 protein and by extension Rpl22p paralog composition according to the cellular demands for ribosome biogenesis. [Rpl22] | Splicing-Mediated Autoregulation Modulates Rpl22p Expression in Saccharomyces cerevisiae. Gabunilas J, Chanfreau G., Free PMC Article | 08/20/2016 |
study brings the first structural characterization, at the residue level, of yeast IF1 in its dimeric form[if1] | Dimerization interface and dynamic properties of yeast IF1 revealed by Site-Directed Spin Labeling EPR spectroscopy. Le Breton N, Adrianaivomananjaona T, Gerbaud G, Etienne E, Bisetto E, Dautant A, Guigliarelli B, Haraux F, Martinho M, Belle V. | 05/7/2016 |
eIF4B and eIF4G jointly stimulate ATP hydrolysis and RNA unwinding by eIF4A and favor the formation of the closed eIF4A conformer.[eIF4A, eIF4B, eIF4G] | eIF4B and eIF4G jointly stimulate eIF4A ATPase and unwinding activities by modulation of the eIF4A conformational cycle. Andreou AZ, Klostermeier D. | 03/1/2014 |
Suggest that the homodimer of Atg38 functions as a physical linkage between the autophagy-specific phosphatidylinositol 3-kinase subcomplexes to facilitate complex I formation. | Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity. Araki Y, Ku WC, Akioka M, May AI, Hayashi Y, Arisaka F, Ishihama Y, Ohsumi Y., Free PMC Article | 12/14/2013 |
This report demonstrates that RNAP-II also transcribes two sequences located in the 5'- and 3'-ends of the 35S rRNA gene that overlap with the sequences of the 35S rRNA precursor transcribed by RNAP-I.[RNAP-II] | RNAP-II transcribes two small RNAs at the promoter and terminator regions of the RNAP-I gene in Saccharomyces cerevisiae. Mayán MD. | 07/13/2013 |
Although YBR159W localizes to the endoplasmic reticulum membrane, subcellular fractionation experiments show that a fraction of eIF2B cofractionates with lipid membranes in a YBR159W-independent manner.[eIF2B] | The yeast eukaryotic translation initiation factor 2B translation initiation complex interacts with the fatty acid synthesis enzyme YBR159W and endoplasmic reticulum membranes. Browne CM, Samir P, Fites JS, Villarreal SA, Link AJ., Free PMC Article | 04/13/2013 |
The Saccharomyces cerevisiae Hot1p regulated gene YHR087W (HGI1) has a role in translation upon high glucose concentration stress. [Yhr087wp] | The Saccharomyces cerevisiae Hot1p regulated gene YHR087W (HGI1) has a role in translation upon high glucose concentration stress. Gomar-Alba M, Jiménez-Martí E, del Olmo M., Free PMC Article | 01/12/2013 |
Synergism of the two Myb domains of Tay1 protein results in high affinity binding to telomeres [Tay1] | Synergism of the two Myb domains of Tay1 protein results in high affinity binding to telomeres. Visacka K, Hofr C, Willcox S, Necasova I, Pavlouskova J, Sepsiova R, Wimmerova M, Simonicova L, Nosek J, Fajkus J, Griffith JD, Tomaska L., Free PMC Article | 12/8/2012 |
Propose that Lnp1p and Sey1p act antagonistically to balance endoplasmic reticular polygonal network formation. | ER network formation requires a balance of the dynamin-like GTPase Sey1p and the Lunapark family member Lnp1p. Chen S, Novick P, Ferro-Novick S., Free PMC Article | 09/8/2012 |
The C-terminal tandem BRCT repeats of Rtt107 interaction with gammaH2A is functionally important during DNA repair. [gammaH2A] | Structure of C-terminal tandem BRCT repeats of Rtt107 protein reveals critical role in interaction with phosphorylated histone H2A during DNA damage repair. Li X, Liu K, Li F, Wang J, Huang H, Wu J, Shi Y., Free PMC Article | 06/16/2012 |