| CD7 activation regulates cytotoxicity-driven pathology in systemic sclerosis, yielding a target for selective cell depletion. | CD7 activation regulates cytotoxicity-driven pathology in systemic sclerosis, yielding a target for selective cell depletion.
Papadimitriou TI, Singh P, van Caam A, Walgreen B, Gorris MAJ, Vitters EL, van Ingen IL, Koenders MI, Smeets RL, Vonk M, de Vries JM, van der Kraan PM, van Oosterhout Y, Huynen MA, Koenen HJPM, Thurlings RM. | 03/15/2024 |
| Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia. | Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia.
Chiesa R, Georgiadis C, Syed F, Zhan H, Etuk A, Gkazi SA, Preece R, Ottaviano G, Braybrook T, Chu J, Kubat A, Adams S, Thomas R, Gilmour K, O'Connor D, Vora A, Qasim W, Base-Edited CAR T Group. | 09/13/2023 |
| T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape. | T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape.
Dai Z, Mu W, Zhao Y, Cheng J, Lin H, Ouyang K, Jia X, Liu J, Wei Q, Wang M, Liu C, Tan T, Zhou J., Free PMC Article | 04/23/2022 |
| CD2 and CD7 are sensitive flow cytometry screening markers for T-lineage acute leukemia(s): a study of 465 acute leukemia cases. | CD2 and CD7 are sensitive flow cytometry screening markers for T-lineage acute leukemia(s): a study of 465 acute leukemia cases.
Rozenova KA, Jevremovic D, Reichard KK, Nguyen P, Otteson GE, Timm MM, Horna P, Olteanu H, Shi M. | 01/1/2022 |
| Quantitative analyses of CD7, CD33, CD34, CD56, and CD123 within the FLT3-ITD/NPM1-MUT myeloblastic/monocytic bulk AML blastic populations. | Quantitative analyses of CD7, CD33, CD34, CD56, and CD123 within the FLT3-ITD/NPM1-MUT myeloblastic/monocytic bulk AML blastic populations.
Soare DS, Radu E, Dumitru I, Vlădăreanu AM, Bumbea H. | 11/6/2021 |
| Prognostic value of lymphoid marker CD7 expression in acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplantation in first morphological complete remission. | Prognostic value of lymphoid marker CD7 expression in acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplantation in first morphological complete remission.
Lv K, Cai C, Chen J, Xu M, Wan L, Zhou M, Du Y, Ma X, Wu X, Tang X, Qiu H, Wu D, Han Y, Liu Y. | 09/25/2021 |
| FLT3-ITD DNA and mRNA levels in AML do not correlate with CD7, CD33 and CD123 expression. | FLT3-ITD DNA and mRNA levels in AML do not correlate with CD7, CD33 and CD123 expression.
Soare DS, Radu E, Dumitru I, Popov VM, Bumbea H, Vlădăreanu AM., Free PMC Article | 05/1/2021 |
| [Expression of CD7 and its correlation with prognosis in patients with NK/T-cell lymphoma]. | [Expression of CD7 and its correlation with prognosis in patients with NK/T-cell lymphoma].
Fu XR, Wan WJ, Sun ZC, Zhang XD, Nan FF, Ge JR, Xia YQ, Zhang MZ., Free PMC Article | 02/6/2021 |
| Dysfunctional immunoregulation in liver allograft rejection patients can be partly attributed to reduced regulatory T-cell Gal1 expression and reduced responder T-cell CD7 expression. | Dysfunctional immunoregulation in human liver allograft rejection associated with compromised galectin-1/CD7 pathway function.
Wei S, Cao D, Liu Z, Li J, Wu H, Gong J, Liu Y, Wu Y., Free PMC Article | 10/26/2019 |
| in acute myeloid leukemia patients the association of CD7 positivity and FLT3 positivity was found to be significant | Correlation of FLT3 mutations with expression of CD7 in acute myeloid leukemia.
Baqai J, Crisan D. | 01/16/2016 |
| Data show that CD7 promotes extramedullary involvement of the B-ALL line Tanoue in an integrin beta2-dependent manner. | CD7 promotes extramedullary involvement of the B-cell acute lymphoblastic leukemia line Tanoue by enhancing integrin β2-dependent cell adhesiveness.
Kondoh T, Kuribayashi K, Tanaka M, Kobayashi D, Yanagihara N, Watanabe N. | 02/28/2015 |
| We showed that the CADM1 versus CD7 plot is capable of discriminating clonally expanding HTLV-I-infected cells in indolent and acute-type T-cell leukemia-lymphomas and in asymptomatic carriers | CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-I-infected cells in adult T-cell leukemia/lymphoma.
Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K. | 01/10/2015 |
| CD7 is present on monocytes and tumor macrophages and its ligand, SECTM1, is frequently expressed in corresponding melanoma tissues | SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway.
Wang T, Ge Y, Xiao M, Lopez-Coral A, Li L, Roesch A, Huang C, Alexander P, Vogt T, Xu X, Hwang WT, Lieu M, Belser E, Liu R, Somasundaram R, Herlyn M, Kaufman RE., Free PMC Article | 05/31/2014 |
| SECTM1 secreted from bone marrow stromal cells may interact with CD7 to influence GM-CSF expression in leukemic cells. | Autocrine GM-CSF transcription in the leukemic progenitor cell line KG1a is mediated by the transcription factor ETS1 and is negatively regulated through SECTM1 mediated ligation of CD7.
Bade-Döding C, Göttmann W, Baigger A, Farren M, Lee KP, Blasczyk R, Huyton T. | 03/29/2014 |
| epigenetic down-regulation of CD7 is associated with acute myeloid leukemia. | CD7 in acute myeloid leukemia: correlation with loss of wild-type CEBPA, consequence of epigenetic regulation.
Röhrs S, Scherr M, Romani J, Zaborski M, Drexler HG, Quentmeier H., Free PMC Article | 08/16/2010 |
| CD7 loss in aggressive natural killer-cell leukemia; a useful diagnostic marker | Frequent CD7 antigen loss in aggressive natural killer-cell leukemia: a useful diagnostic marker.
Yoo EH, Kim HJ, Lee ST, Kim WS, Kim SH. | 06/28/2010 |
| low expression in T-cell lymphomas due to Twist2-mediated suppression of promoter activity; enhanced by histone deacetylase inhibitors | Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells.
Koh HS, Lee C, Lee KS, Park EJ, Seong RH, Hong S, Jeon SH. | 06/14/2010 |
| These findings indicate a link between epigenetic modifications and CD7 expression in primitive chronic myeloid leukemia cells. | Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia.
Rogers SL, Zhao Y, Jiang X, Eaves CJ, Mager DL, Rouhi A., Free PMC Article | 05/31/2010 |
| the galectin-1 glycoprotein receptor CD7 maybe a novel target for GdA on T cells. | Glycodelin A triggers T cell apoptosis through a novel calcium-independent galactose-binding lectin activity.
SundarRaj S, Soni C, Karande AA. | 01/21/2010 |
| The CD7 expression in CD4(+) T cells discriminates between HL and reactive LAD, suggesting that this could be a useful and practical adjunctive tool in the diagnosis of Hodgkin lymphoma. | Overexpression of CD7 in classical Hodgkin lymphoma-infiltrating T lymphocytes.
Seegmiller AC, Karandikar NJ, Kroft SH, McKenna RW, Xu Y. | 01/21/2010 |
| by down-regulating CD7, ATLL cells could have escaped Gal-3-induced apoptosis to run a more aggressive clinical course | Loss of CD7, independent of galectin-3 expression, implies a worse prognosis in adult T-cell leukaemia/lymphoma.
Liu TY, Chen CY, Tien HF, Lin CW. | 01/21/2010 |
| close association of aberrant CD7 expression and FLT3/ITD mutation in the myeloblasts of FLT3/ITD+ acute myeloid leukemia suggests that FLT3/ITD- mediated leukemic transformation occurs in the more early stage of myeloid progenitor cells | Aberrant expression of CD7 in myeloblasts is highly associated with de novo acute myeloid leukemias with FLT3/ITD mutation.
Rausei-Mills V, Chang KL, Gaal KK, Weiss LM, Huang Q. | 01/21/2010 |
| differential levels of CD7 identify the progressive stages of lineage commitment in human thymus, initiated from a primitive CD7(-) lympho-myeloid thymic progenitor | Human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7- lympho-myeloid thymic progenitors.
Hao QL, George AA, Zhu J, Barsky L, Zielinska E, Wang X, Price M, Ge S, Crooks GM., Free PMC Article | 01/21/2010 |
| Patients expressing CD7 had significant shorter disease free (DFS) and post-remission survivals (PRS) than patients without CD7 (DFS of 12 months versus 42 months, P=0.005; PRS of 15 months versus 33 months, P=0.013). | CD7 expression predicts poor disease free survival and post-remission survival in patients with acute myeloid leukemia and normal karyotype.
Chang H, Yeung J, Brandwein J, Yi QL. | 01/21/2010 |
| HTLV-IInfected cells acquired a profound decrease of intracellular calcium levels in response to ionomycin, timely correlated with decreased CD7 expression | HTLV-I infection of WE17/10 CD4+ cell line leads to progressive alteration of Ca2+ influx that eventually results in loss of CD7 expression and activation of an antiapoptotic pathway involving AKT and BAD which paves the way for malignant transformation.
Akl H, Badran BM, Zein NE, Bex F, Sotiriou C, Willard-Gallo KE, Burny A, Martiat P. | 01/21/2010 |