| beta-COP Suppresses the Surface Expression of the TREK2. | β-COP Suppresses the Surface Expression of the TREK2.
Kim SS, Park J, Kim E, Hwang EM, Park JY., Free PMC Article | 06/14/2023 |
| Comprehensive analysis reveals COPB2 and RYK associated with tumor stages of larynx squamous cell carcinoma. | Comprehensive analysis reveals COPB2 and RYK associated with tumor stages of larynx squamous cell carcinoma.
Zhou G, Zhang S, Jin M, Hu S., Free PMC Article | 07/2/2022 |
| An Integrative Pan-Cancer Analysis of the Oncogenic Role of COPB2 in Human Tumors. | An Integrative Pan-Cancer Analysis of the Oncogenic Role of COPB2 in Human Tumors.
Wu B, Wu Y, Guo X, Yue Y, Li Y, He X, Chen Y, Zhao W, Liu J, Wu X, Shen A, Zhang S., Free PMC Article | 02/12/2022 |
| COPB2: a transport protein with multifaceted roles in cancer development and progression. | COPB2: a transport protein with multifaceted roles in cancer development and progression.
Feng Y, Lei X, Zhang L, Wan H, Pan H, Wu J, Zou M, Zhu L, Mi Y., Free PMC Article | 01/15/2022 |
| COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay. | COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay.
Marom R, Burrage LC, Venditti R, Clément A, Blanco-Sánchez B, Jain M, Scott DA, Rosenfeld JA, Sutton VR, Shinawi M, Mirzaa G, DeVile C, Roberts R, Calder AD, Allgrove J, Grafe I, Lanza DG, Li X, Joeng KS, Lee YC, Song IW, Sliepka JM, Batkovskyte D, Washington M, Dawson BC, Jin Z, Jiang MM, Chen S, Chen Y, Tran AA, Emrick LT, Murdock DR, Hanchard NA, Zapata GE, Mehta NR, Weis MA, Scott AA, Tremp BA, Phillips JB, Wegner J, Taylor-Miller T, Gibbs RA, Muzny DM, Jhangiani SN, Hicks J, Stottmann RW, Dickinson ME, Seavitt JR, Heaney JD, Eyre DR, Undiagnosed Diseases Network, Westerfield M, De Matteis MA, Lee B., Free PMC Article | 09/18/2021 |
| High expression of COPB2 predicts adverse outcomes: A potential therapeutic target for glioma. | High expression of COPB2 predicts adverse outcomes: A potential therapeutic target for glioma.
Zhou Y, Wang X, Huang X, Li XD, Cheng K, Yu H, Zhou YJ, Lv P, Jiang XB., Free PMC Article | 07/3/2021 |
| COPB2: A Novel Prognostic Biomarker That Affects Progression of HCC. | COPB2: A Novel Prognostic Biomarker That Affects Progression of HCC.
Zhang J, Wang X, Li G, He J, Lu Z, Yang Y, Jiang Y, Jiang L, Li F, Liu J., Free PMC Article | 05/29/2021 |
| MiR-216a-3p regulates the proliferation, apoptosis, migration, and invasion of lung cancer cells via targeting COPB2. | MiR-216a-3p regulates the proliferation, apoptosis, migration, and invasion of lung cancer cells via targeting COPB2.
Wang X, Shi J, Niu Z, Wang J, Zhang W. | 05/1/2021 |
| COPB2 gene silencing inhibits colorectal cancer cell proliferation and induces apoptosis via the JNK/c-Jun signaling pathway. | COPB2 gene silencing inhibits colorectal cancer cell proliferation and induces apoptosis via the JNK/c-Jun signaling pathway.
Wang Y, Xie G, Li M, Du J, Wang M., Free PMC Article | 12/19/2020 |
| Upregulation of the Coatomer Protein Complex Subunit beta 2 (COPB2) Gene Targets microRNA-335-3p in NCI-H1975 Lung Adenocarcinoma Cells to Promote Cell Proliferation and Migration. | Upregulation of the Coatomer Protein Complex Subunit beta 2 (COPB2) Gene Targets microRNA-335-3p in NCI-H1975 Lung Adenocarcinoma Cells to Promote Cell Proliferation and Migration.
Pu X, Jiang H, Li W, Xu L, Wang L, Shu Y., Free PMC Article | 11/28/2020 |
| COPB2 is up-regulated in breast cancer and plays a vital role in the metastasis via N-cadherin and Vimentin. | COPB2 is up-regulated in breast cancer and plays a vital role in the metastasis via N-cadherin and Vimentin.
Bhandari A, Zheng C, Sindan N, Sindan N, Quan R, Xia E, Thapa Y, Tamang D, Wang O, Ye X, Huang D., Free PMC Article | 08/15/2020 |
| BMSCs-derived exosome miR-4461 downregulated COPB2 expression and inhibited HCT116 and SW480 cells migration and invasion | MicroRNA-4461 derived from bone marrow mesenchymal stem cell exosomes inhibits tumorigenesis by downregulating COPB2 expression in colorectal cancer.
Chen HL, Li JJ, Jiang F, Shi WJ, Chang GY. | 03/7/2020 |
| COPB2 is highly expressed in cholangiocellular carcinoma cell lines. | Downregulation of COPB2 by RNAi inhibits growth of human cholangiocellular carcinoma cells.
Li ZS, Liu CH, Liu Z, Zhu CL, Huang Q. | 11/9/2019 |
| Study demonstrated that COPB2 was highly expressed in human gastric cancer cell lines, and knockdown suppressed colony formation and promoted cell apoptosis via inhibiting the RTK signaling and its downstream signaling cascade molecules. | Silencing of COPB2 inhibits the proliferation of gastric cancer cells and induces apoptosis via suppression of the RTK signaling pathway.
An C, Li H, Zhang X, Wang J, Qiang Y, Ye X, Li Q, Guan Q, Zhou Y., Free PMC Article | 08/31/2019 |
| Knockdown of ERC1, RAB4B, COPA, and COPB2, caused profound loss of virus production. | Identification of Host Factors Involved in Human Cytomegalovirus Replication, Assembly, and Egress Using a Two-Step Small Interfering RNA Screen.
McCormick D, Lin YT, Grey F., Free PMC Article | 01/26/2019 |
| The increased expression of COPB2 was significantly correlated with the progression of lung adenocarcinoma. | COPB2 promotes cell proliferation and tumorigenesis through up-regulating YAP1 expression in lung adenocarcinoma cells.
Pu X, Wang J, Li W, Fan W, Wang L, Mao Y, Yang S, Liu S, Xu J, Lv Z, Xu L, Shu Y. | 10/13/2018 |
| High expression of COPB2 was found in prostate cancer tissue and was related to poor overall survival based on a public dataset. Cell proliferation was significantly inhibited in COPB2-knockdown CWR22RV1 cells, as demonstrated by CCK8 and colony formation assays. | Coatomer subunit beta 2 (COPB2), identified by label-free quantitative proteomics, regulates cell proliferation and apoptosis in human prostate carcinoma cells.
Mi Y, Sun C, Wei B, Sun F, Guo Y, Hu Q, Ding W, Zhu L, Xia G. | 01/6/2018 |
| COPB2 significantly promoted PC-3 cell proliferation and colony formation through the cell cycle and apoptosis pathway. COPB2 showed a clinical correlation and may serve as a biomarker for the detection for prostate cancer. | COPB2 Is Upregulated in Prostate Cancer and Regulates PC-3 Cell Proliferation, Cell Cycle, and Apoptosis.
Mi Y, Yu M, Zhang L, Sun C, Wei B, Ding W, Zhu Y, Tang J, Xia G, Zhu L. | 05/27/2017 |
| these data suggest that beta-COP plays a critical role in the forward transport of TREK1 channel to the plasma membrane. | Enhancement of TREK1 channel surface expression by protein-protein interaction with beta-COP.
Kim E, Hwang EM, Yarishkin O, Yoo JC, Kim D, Park N, Cho M, Lee YS, Sun CH, Yi GS, Yoo J, Kang D, Han J, Hong SG, Park JY. | 06/28/2010 |
| Golgi organization depends on mutually interacting domains in betaCOP and p115, suggesting that vesicle tethering at the Golgi involves p115 binding to the COPI coat | Coat-tether interaction in Golgi organization.
Guo Y, Punj V, Sengupta D, Linstedt AD., Free PMC Article | 01/21/2010 |