| Publisher Correction: MiR-21 and miR-183 can simultaneously target SOCS6 and modulate growth and invasion of hepatocellular carcinoma (HCC) cells. | Publisher Correction: MiR-21 and miR-183 can simultaneously target SOCS6 and modulate growth and invasion of hepatocellular carcinoma (HCC) cells.
Li ZB, Li ZZ, Li L, Chu HT, Jia M. | 07/22/2024 |
| Extracellular vesicle-encapsulated microRNA-296-3p from cancer-associated fibroblasts promotes ovarian cancer development through regulation of the PTEN/AKT and SOCS6/STAT3 pathways. | Extracellular vesicle-encapsulated microRNA-296-3p from cancer-associated fibroblasts promotes ovarian cancer development through regulation of the PTEN/AKT and SOCS6/STAT3 pathways.
Sun L, Ke M, Yin M, Zeng Y, Ji Y, Hu Y, Fu S, Zhang C., Free PMC Article | 01/31/2024 |
| Methyltransferase-like 3 facilitates lung cancer progression by accelerating m6A methylation-mediated primary miR-663 processing and impeding SOCS6 expression. | Methyltransferase-like 3 facilitates lung cancer progression by accelerating m6A methylation-mediated primary miR-663 processing and impeding SOCS6 expression.
Li S, Lu X, Zheng D, Chen W, Li Y, Li F. | 10/29/2022 |
| MicroRNA-494-3p Exacerbates Renal Epithelial Cell Dysfunction by Targeting SOCS6 under High Glucose Treatment. | MicroRNA-494-3p Exacerbates Renal Epithelial Cell Dysfunction by Targeting SOCS6 under High Glucose Treatment.
Xue X, Liu M, Wang Y, Yang Y, Li Z, Shi R, Miao Y. | 04/16/2022 |
| Down-regulation of SOCS6: an unfavorable prognostic factor for gastrointestinal stromal tumor proven by survival analysis. | Down-regulation of SOCS6: an unfavorable prognostic factor for gastrointestinal stromal tumor proven by survival analysis.
Ouyang J, An T, Wang Y, Lu X, Zhang Y, Wang X, Zhang X, Zhang C., Free PMC Article | 03/19/2022 |
| Circ_0085289 Alleviates the Progression of Periodontitis by Regulating let-7f-5p/SOCS6 Pathway. | Circ_0085289 Alleviates the Progression of Periodontitis by Regulating let-7f-5p/SOCS6 Pathway.
Du W, Wang L, Liao Z, Wang J. | 12/25/2021 |
| Circular RNA circ_103820 suppresses lung cancer tumorigenesis by sponging miR-200b-3p to release LATS2 and SOCS6. | Circular RNA circ_103820 suppresses lung cancer tumorigenesis by sponging miR-200b-3p to release LATS2 and SOCS6.
Chi Y, Zheng W, Bao G, Wu L, He X, Gan R, Shen Y, Yin X, Jin M., Free PMC Article | 09/25/2021 |
| Inhibition of miR-1298-5p attenuates sepsis lung injury by targeting SOCS6. | Inhibition of miR-1298-5p attenuates sepsis lung injury by targeting SOCS6.
Ma J, Xu LY, Sun QH, Wan XY, BingLi. | 09/4/2021 |
| Inhibition of SOCS6 confers radioresistance in esophageal squamous cell carcinoma. | Inhibition of SOCS6 confers radioresistance in esophageal squamous cell carcinoma.
Ma R, Shi M, Hu J, Zhao LN. | 06/26/2021 |
| miR-155-5p Implicates in the Pathogenesis of Renal Fibrosis via Targeting SOCS1 and SOCS6. | miR-155-5p Implicates in the Pathogenesis of Renal Fibrosis via Targeting SOCS1 and SOCS6.
Zhang W, Li X, Tang Y, Chen C, Jing R, Liu T., Free PMC Article | 02/6/2021 |
| microRNA-454 promotes liver tumor-initiating cell expansion by regulating SOCS6. | microRNA-454 promotes liver tumor-initiating cell expansion by regulating SOCS6.
Lei Z, Tang X, Si A, Yang P, Wang L, Luo T, Guo G, Zhang Q, Cheng Z. | 12/12/2020 |
| Study is the first to illustrate that miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate NSCLC cell proliferation and apoptosis, and is a potential biomarker and therapeutic target for NSCLC. | miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC.
Xia Y, Wei K, Yang FM, Hu LQ, Pan CF, Pan XL, Wu WB, Wang J, Wen W, He ZC, Xu J, Xu XF, Zhu Q, Chen L., Free PMC Article | 06/6/2020 |
| FGD5-AS1/miR-142-3p/SOCS6 axis may act as an important indicator | Abnormal expression of long noncoding RNA FGD5-AS1 affects the development of periodontitis through regulating miR-142-3p/SOCS6/NF-κB pathway.
Chen H, Lan Z, Li Q, Li Y. | 11/23/2019 |
| Low SOCS6 expression is associated with Prostate Cancer. | SOCS6 Functions as a Tumor Suppressor by Inducing Apoptosis and Inhibiting Angiogenesis in Human Prostate Cancer.
Yuan D, Wang W, Su J, Zhang Y, Luan B, Rao H, Cheng T, Zhang W, Xiao S, Zhang M, Jiang FN, Sun Z, Jia Z, Zhong WD, Zhu J. | 10/5/2019 |
| Together, our data provide important evidence for miR-19 mediated SOCS6 in OS growth and revealed miR-19/SOCS6/JAK2/STAT3 pathway as a potential therapeutic strategy for OS patients. | miR-19 promotes osteosarcoma progression by targeting SOCS6.
Sun Z, Liu Q, Hong H, Zhang H, Zhang T. | 12/30/2017 |
| Results indicate that similar to PTEN pseudogene (PTENP1), suppressor of cytokine signaling 6 protein (SOCS6) expression was also significantly lower in esophageal squamous cell carcinoma (ESCC) samples. | PTENP1 inhibits the growth of esophageal squamous cell carcinoma by regulating SOCS6 expression and correlates with disease prognosis.
Gong T, Zheng S, Huang S, Fu S, Zhang X, Pan S, Yang T, Sun Y, Wang Y, Hui B, Guo J, Zhang X., Free PMC Article | 12/9/2017 |
| our results describe for the first time the role of miR-494-3p during normal hematopoietic stem/progenitor cells differentiation and suggest that its increased expression, and the subsequent downregulation of its target SOCS6, might contribute to the megakaryocyte hyperplasia commonly observed in primary myelofibrosis patients. | miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6.
Rontauroli S, Norfo R, Pennucci V, Zini R, Ruberti S, Bianchi E, Salati S, Prudente Z, Rossi C, Rosti V, Guglielmelli P, Barosi G, Vannucchi A, Tagliafico E, Manfredini R., Free PMC Article | 10/14/2017 |
| miR-142-3p regulates NPC development by down-regulating SOCS6 expression and suggest that modulation of miR-142-3p expression could be a therapeutic strategy for NPC | MiR-142-3p Suppresses SOCS6 Expression and Promotes Cell Proliferation in Nasopharyngeal Carcinoma.
Qi X, Li J, Zhou C, Lv C, Tian M. | 05/21/2016 |
| Stage-independent downregulation of SOCS2 and SOCS6 correlate with disease-free survival in colorectal cancer. | Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer.
Letellier E, Schmitz M, Baig K, Beaume N, Schwartz C, Frasquilho S, Antunes L, Marcon N, Nazarov PV, Vallar L, Even J, Haan S., Free PMC Article | 10/11/2014 |
| Studied both the function of upregulated miR-424-5p in pancreatic cancer and how downstream suppressor of cytokine-induced signaling 6 (SOCS6) is negatively regulated by miR-424-5p. | MicroRNA-424-5p suppresses the expression of SOCS6 in pancreatic cancer.
Wu K, Hu G, He X, Zhou P, Li J, He B, Sun W. | 10/4/2014 |
| miR-17-5p might function as a pro-proliferative factor by repressing SOCS6 in gastric cancer | miR-17-5p promotes proliferation by targeting SOCS6 in gastric cancer cells.
Wu Q, Luo G, Yang Z, Zhu F, An Y, Shi Y, Fan D. | 07/19/2014 |
| SOCS2 and SOCS6 expression are remarkably reduced in hepatocellular carcinoma and correlate with aggressive tumor progression and poor prognosis | Reduced expression of SOCS2 and SOCS6 in hepatocellular carcinoma correlates with aggressive tumor progression and poor prognosis.
Qiu X, Zheng J, Guo X, Gao X, Liu H, Tu Y, Zhang Y. | 11/16/2013 |
| Results show that SOCS6 forms complex with DRP1 and the mitochondrial phosphatase PGAM5, attenuates DRP1 phosphorylation, and promotes DRP1 mitochondrial translocation. | Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation.
Lin HY, Lai RH, Lin ST, Lin RC, Wang MJ, Lin CC, Lee HC, Wang FF, Chen JY., Free PMC Article | 08/31/2013 |
| SOCS6 negatively regulates Flt3 activation, the downstream Erk signaling pathway, and cell proliferation. | Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3.
Kazi JU, Sun J, Phung B, Zadjali F, Flores-Morales A, Rönnstrand L., Free PMC Article | 12/29/2012 |
| Reduced copy number and mRNA expression of SOCS6 are associated with disease recurrence in primary lung squamous cell carcinoma and may be useful prognostic biomarkers. | Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma.
Sriram KB, Larsen JE, Savarimuthu Francis SM, Wright CM, Clarke BE, Duhig EE, Brown KM, Hayward NK, Yang IA, Bowman RV, Fong KM., Free PMC Article | 06/30/2012 |