| KIF3B gene silent variant leading to sperm morphology and motility defects and male infertilitydagger. | KIF3B gene silent variant leading to sperm morphology and motility defects and male infertility†.
Heydari R, Seresht-Ahmadi M, Mirshahvaladi S, Sabbaghian M, Mohseni-Meybodi A. | 05/14/2022 |
| Circular RNA circ_0032462 Enhances Osteosarcoma Cell Progression by Promoting KIF3B Expression. | Circular RNA circ_0032462 Enhances Osteosarcoma Cell Progression by Promoting KIF3B Expression.
Gu R, Li X, Yan X, Feng Z, Hu A., Free PMC Article | 12/4/2021 |
| Identification of kinesin family member 3B (KIF3B) as a molecular target for gastric cancer. | Identification of kinesin family member 3B (KIF3B) as a molecular target for gastric cancer.
Yao FZ, Kong DG. | 07/17/2021 |
| LEF-AS1 participates in occurrence of colorectal cancer through adsorbing miR-505 and promoting KIF3B expression. | LEF-AS1 participates in occurrence of colorectal cancer through adsorbing miR-505 and promoting KIF3B expression.
Gong XY, Huang AL. | 12/19/2020 |
| Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy. | Mutations in the Kinesin-2 Motor KIF3B Cause an Autosomal-Dominant Ciliopathy.
Cogné B, Latypova X, Senaratne LDS, Martin L, Koboldt DC, Kellaris G, Fievet L, Le Meur G, Caldari D, Debray D, Nizon M, Frengen E, Bowne SJ, 99 Lives Consortium, Cadena EL, Daiger SP, Bujakowska KM, Pierce EA, Gorin M, Katsanis N, Bézieau S, Petersen-Jones SM, Occelli LM, Lyons LA, Legeai-Mallet L, Sullivan LS, Davis EE, Isidor B., Free PMC Article | 10/10/2020 |
| miR-127-3p was downregulated in oral squamous cell carcinoma (OSCC) tissues and was associated with malignant clinicopathological features and poor prognosis. KIF3B was confirmed to be a direct target of miR-127-3p. Upregulation of KIF3B observed in OSCC promoted tumorigenesis. miR-127-3p targeted KIF3B to inhibit the development of OSCC by suppressing cell proliferation, migration and invasion. | MiR-127-3p targets KIF3B to inhibit the development of oral squamous cell carcinoma.
Ji L, Zhu ZN, He CJ, Shen X. | 07/25/2020 |
| Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia. | Kinesin Kif3b mutation reduces NMDAR subunit NR2A trafficking and causes schizophrenia-like phenotypes in mice.
Alsabban AH, Morikawa M, Tanaka Y, Takei Y, Hirokawa N., Free PMC Article | 07/18/2020 |
| High KIF3B expression is associated with Pancreatic Cancer. | KIF3B Promotes the Proliferation of Pancreatic Cancer.
Liu ZH, Dong SX, Jia JH, Zhang ZL, Zhen ZG. | 02/8/2020 |
| The rate of transport is set by an equilibrium between a faster state, where only kinesin family member 17 protein (KIF17) motors move the train, and a slower state, where at least one kinesin family member 3A/B protein (KIF3AB) motor on the train remains active in transport. | Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.
Milic B, Andreasson JOL, Hogan DW, Block SM., Free PMC Article | 06/2/2018 |
| High KIF3B expression is associated with seminoma. | A novel role of KIF3b in the seminoma cell cycle.
Shen HQ, Xiao YX, She ZY, Tan FQ, Yang WX. | 06/3/2017 |
| These data suggest that GLI interactions with KIF3A-KIF3B-KAP3 complexes are essential for proper GLI transcriptional activity. | The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.
Carpenter BS, Barry RL, Verhey KJ, Allen BL., Free PMC Article | 12/26/2015 |
| Results suggest that KIF3B expression was upregulated in HCC tumor tissues and proliferating HCC cells, and an increasd KIF3B expression was associated with poor overall survival. | Suppression of KIF3B expression inhibits human hepatocellular carcinoma proliferation.
Huang X, Liu F, Zhu C, Cai J, Wang H, Wang X, He S, Liu C, Yao L, Ding Z, Zhang Y, Zhang T., Free PMC Article | 05/24/2014 |
| KIF3B is involved in the trafficking of kAE1 to the plasma membrane of human kidney alpha-intercalated cells. | Human kidney anion exchanger 1 interacts with kinesin family member 3B (KIF3B).
Duangtum N, Junking M, Sawasdee N, Cheunsuchon B, Limjindaporn T, Yenchitsomanus PT. | 11/19/2011 |
| Interaction with KIF3B alters CLC-5 cell surface expression, chloride current, and alters albumin endocytosis. Interaction with KIF3B facilitates microtubular transport and endocytosis of CLC-5-containing vesicles away from cell surface. | CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease.
Reed AA, Loh NY, Terryn S, Lippiat JD, Partridge C, Galvanovskis J, Williams SE, Jouret F, Wu FT, Courtoy PJ, Nesbit MA, Rorsman P, Devuyst O, Ashcroft FM, Thakker RV., Free PMC Article | 03/15/2010 |
| Data indicate that p0071 and Ect2 are transported via distinct motors and identify a novel pathway implicating KIF3 in the regulation of actin organization during cytokinesis | Targeting of p0071 to the midbody depends on KIF3.
Keil R, Kiessling C, Hatzfeld M. | 01/21/2010 |
| Rip11/FIP5-kinesin-II complex plays a key role in the routing of internalized receptors through the perinuclear recycling endosomes. | The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling.
Schonteich E, Wilson GM, Burden J, Hopkins CR, Anderson K, Goldenring JR, Prekeris R., Free PMC Article | 01/21/2010 |
| kinesin-2 is a linker between polycystin-2(PC2) and fibrocystin and mediates the regulation of PC2 channel function by fibrocystin | Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin.
Wu Y, Dai XQ, Li Q, Chen CX, Mai W, Hussain Z, Long W, Montalbetti N, Li G, Glynne R, Wang S, Cantiello HF, Wu G, Chen XZ. | 01/21/2010 |
| both motor domains of KIF3A/B coordinate for processive motility and move at different speeds | The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds.
Zhang Y, Hancock WO., Free PMC Article | 10/3/2015 |
| Interaction of KIF3A/3B with KAP3 may be important for the proper progression of mitosis. | Role of the kinesin-2 family protein, KIF3, during mitosis.
Haraguchi K, Hayashi T, Jimbo T, Yamamoto T, Akiyama T. | 01/21/2010 |