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    dps DNA protection during starvation protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945101, updated on 3-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Bridging DNA contacts allow Dps from E. coli to condense DNA.

    Bridging DNA contacts allow Dps from E. coli to condense DNA.
    Shahu S, Vtyurina N, Das M, Meyer AS, Ganji M, Abbondanzieri EA., Free PMC Article

    06/3/2024
    Multi-crystal data collection using synchrotron radiation as exemplified with low-symmetry crystals of Dps.

    Multi-crystal data collection using synchrotron radiation as exemplified with low-symmetry crystals of Dps.
    Kovalenko V, Popov A, Santoni G, Loiko N, Tereshkina K, Tereshkin E, Krupyanskii Y., Free PMC Article

    07/31/2021
    Structural Rearrangement of Dps-DNA Complex Caused by Divalent Mg and Fe Cations.

    Structural Rearrangement of Dps-DNA Complex Caused by Divalent Mg and Fe Cations.
    Dadinova L, Kamyshinsky R, Chesnokov Y, Mozhaev A, Matveev V, Gruzinov A, Vasiliev A, Shtykova E., Free PMC Article

    07/17/2021
    Spatial organization of Dps and DNA-Dps complexes.

    Spatial organization of Dps and DNA-Dps complexes.
    Dubrovin EV, Dadinova LA, Petoukhov MV, Soshinskaya EY, Mozhaev AA, Klinov DV, Schäffer TE, Shtykova EV, Batishchev OV.

    06/19/2021
    A double-alanine mutant of E. coli Dps protein is unable to assemble into a cage due to disruption of key protein-protein interactions. Randomization of residues surrounding the double mutation afforded a repacked interface and proteins with recovered cage formation.

    A Structure-Based Assembly Screen of Protein Cage Libraries in Living Cells: Experimentally Repacking a Protein-Protein Interface To Recover Cage Formation in an Assembly-Frustrated Mutant.
    Cornell TA, Ardejani MS, Fu J, Newland SH, Zhang Y, Orner BP.

    06/2/2018
    three new candidates of E. coli nucleoid, namely DNA-binding protein from starved cells (Dps), host factor for phage Qbeta (Hfq) and suppressor of td(-) phenotype A (StpA)

    Growth phase dependent changes in the structure and protein composition of nucleoid in Escherichia coli.
    Talukder A, Ishihama A.

    07/30/2016
    Oxidative stress response proteins such as AhpF, Dps, and Fur, all of which belong to the oxyR regulon, were upregulated in Escherichia coli isolates from mice fed the lactose-rich diet.

    Impact of nutritional factors on the proteome of intestinal Escherichia coli: induction of OxyR-dependent proteins AhpF and Dps by a lactose-rich diet.
    Rothe M, Alpert C, Engst W, Musiol S, Loh G, Blaut M., Free PMC Article

    08/18/2012
    study investigated the role key protein-protein interactions play in the assembly and stability of the DPS mini-ferritin

    Rational disruption of the oligomerization of the mini-ferritin E. coli DPS through protein-protein interface mutation.
    Zhang Y, Fu J, Chee SY, Ang EX, Orner BP., Free PMC Article

    04/7/2012
    Unexpectedly, the authors found that dps expression is directly repressed by Mn(2+)-MntR.

    The Escherichia coli K-12 MntR miniregulon includes dps, which encodes the major stationary-phase DNA-binding protein.
    Yamamoto K, Ishihama A, Busby SJ, Grainger DC., Free PMC Article

    04/23/2011
    In contrast, cells lacking Dps exhibited increased cellular copper concentrations compared to their wild-type parent.

    The Dps protein of Escherichia coli is involved in copper homeostasis.
    Thieme D, Grass G.

    04/12/2010
    Dps protected DNA from acid damage by binding to DNA. Dps maintains or forms alpha-helices that are important for Dps-DNA complex formation.

    Acid stress damage of DNA is prevented by Dps binding in Escherichia coli O157:H7.
    Jeong KC, Hung KF, Baumler DJ, Byrd JJ, Kaspar CW., Free PMC Article

    01/21/2010
    Data suggest thatDps acts as a checkpoint during oxidative stress to reduce initiations, providing an opportunity for mechanisms to repair oxidative DNA damage.

    Escherichia coli Dps interacts with DnaA protein to impede initiation: a model of adaptive mutation.
    Chodavarapu S, Gomez R, Vicente M, Kaguni JM.

    01/21/2010
    Fis and H-NS selectively repress the dps promoter, preventing transcription initiation by RNA polymerase.

    Selective repression by Fis and H-NS at the Escherichia coli dps promoter.
    Grainger DC, Goldberg MD, Lee DJ, Busby SJ.

    01/21/2010
    N-terminus verified by Edman degradation on mature peptideSee all PubMed (3) articles11/5/2007
    We describe Escherichia coli survival following neutrophil phagocytosis among three mutants deleted respectively for araB, dps or oxyR.

    Neutrophil microbicidal activity: screening bacterial mutants for survival after phagocytosis using quantitative PCR.
    Rosen H, Lewis PJ, Nitzel CM.

    01/21/2010
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