| OxyR Is a Convergent Target for Mutations Acquired during Adaptation to Oxidative Stress-Prone Metabolic States. | OxyR Is a Convergent Target for Mutations Acquired during Adaptation to Oxidative Stress-Prone Metabolic States.
Anand A, Chen K, Catoiu E, Sastry AV, Olson CA, Sandberg TE, Seif Y, Xu S, Szubin R, Yang L, Feist AM, Palsson BO., Free PMC Article | 11/21/2020 |
| The authors have determined how ElaB is regulated under oxidative stress: RpoS and OxyR coordinately control the expression of inner membrane protein ElaB. | Resistance to oxidative stress by inner membrane protein ElaB is regulated by OxyR and RpoS.
Guo Y, Li Y, Zhan W, Wood TK, Wang X., Free PMC Article | 05/25/2019 |
| Constitutive expression of the OxyR regulon confers the maximum HOCl resistance. | Evolution of Escherichia coli for maximum HOCl resistance through constitutive expression of the OxyR regulon.
Gundlach J, Winter J. | 04/4/2015 |
| The isogenic oxyR mutant exhibited increased H2O2 sensitivity, indistinguishable in vitro growth, and attenuated virulence in rodent models of urinary tract, subcutaneous infection, and systemic sepsis. | OxyR contributes to the virulence of a Clonal Group A Escherichia coli strain (O17:K+:H18) in animal models of urinary tract infection, subcutaneous infection, and systemic sepsis.
Johnson JR, Russo TA, Drawz SM, Clabots C, Olson R, Kuskowski MA, Rosen H. | 05/10/2014 |
| Oxidative stress response proteins such as AhpF, Dps, and Fur, all of which belong to the oxyR regulon, were upregulated in Escherichia coli isolates from mice fed the lactose-rich diet. | Impact of nutritional factors on the proteome of intestinal Escherichia coli: induction of OxyR-dependent proteins AhpF and Dps by a lactose-rich diet.
Rothe M, Alpert C, Engst W, Musiol S, Loh G, Blaut M., Free PMC Article | 08/18/2012 |
| OxyR serves as a master regulator of S-nitrosylation, and alternative posttranslational modifications of OxyR control distinct transcriptional responses | Endogenous protein S-Nitrosylation in E. coli: regulation by OxyR.
Seth D, Hausladen A, Wang YJ, Stamler JS., Free PMC Article | 05/12/2012 |
| OxyR seems to be a factor stimulating lambda prophage maintenance under conditions of oxidative stress. | Influence of the Escherichia coli oxyR gene function on lambda prophage maintenance.
Glinkowska M, Loś JM, Szambowska A, Czyz A, Całkiewicz J, Herman-Antosiewicz A, Wróbel B, Wegrzyn G, Wegrzyn A, Loś M., Free PMC Article | 10/23/2010 |
| Data suggest that the redox state of OxyR and Fnr modulates their interaction with the vgb promoter. | Redox-mediated interactions of VHb (Vitreoscilla haemoglobin) with OxyR: novel regulation of VHb biosynthesis under oxidative stress.
Anand A, Duk BT, Singh S, Akbas MY, Webster DA, Stark BC, Dikshit KL. | 05/10/2010 |
| The data support a model in which in an ON-phase cell, the subcellular OxyR availability at the replication fork as it passes through the agn43 regulatory region is key for initiating an ON-to-OFF switch. | Establishing and maintaining sequestration of Dam target sites for phase variation of agn43 in Escherichia coli.
Kaminska R, van der Woude MW., Free PMC Article | 04/12/2010 |
| deletion mutant strains fail to enhance oxidative stress resistance following treatment with tannin and quercetin | Influence of polyphenols on Escherichia coli resistance to oxidative stress.
Smirnova GV, Samoylova ZY, Muzyka NG, Oktyabrsky ON. | 01/21/2010 |
| study examined the contribution of residues at the dimer interface of the transcriptional regulator OxyR to oligomerization | The oligomerization of OxyR in Escherichia coli.
Knapp GS, Tsai JW, Hu JC., Free PMC Article | 01/21/2010 |
| Here both FNR and OxyR are shown to regulate expression of the E. coli yhjA gene. | The Escherichia coli yhjA gene, encoding a predicted cytochrome c peroxidase, is regulated by FNR and OxyR.
Partridge JD, Poole RK, Green J. | 01/21/2010 |
| N-terminus verified by Edman degradation on complete protein | Purification and characterization of the Escherichia coli OxyR protein, the positive regulator for a hydrogen peroxide-inducible regulon.
Tao K, Makino K, Yonei S, Nakata A, Shinagawa H. | 11/5/2007 |
| Molecular dynamics (MD) simulations have been performed on the regulatory domain of the Escherichia coli OxyR transcription factor for the different chemical states along the mechanistic cycle for its activation by hydrogen peroxide. | A combined molecular dynamics simulation and quantum chemical study on the mechanism for activation of the OxyR transcription factor by hydrogen peroxide.
Kóna J, Brinck T. | 01/21/2010 |
| OxyR activation requires specific disulfide bond formation and that the rapid kinetic reaction path and conformation strain, respectively, drive the oxidation and reduction of OxyR | Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path.
Lee C, Lee SM, Mukhopadhyay P, Kim SJ, Lee SC, Ahn WS, Yu MH, Storz G, Ryu SE. | 01/21/2010 |
| We describe Escherichia coli survival following neutrophil phagocytosis among three mutants deleted respectively for araB, dps or oxyR. | Neutrophil microbicidal activity: screening bacterial mutants for survival after phagocytosis using quantitative PCR.
Rosen H, Lewis PJ, Nitzel CM. | 01/21/2010 |
| OxyR binds to cis-acting oxidant-responsive elements of the sufA promoter under oxidative stress conditions. | IscR acts as an activator in response to oxidative stress for the suf operon encoding Fe-S assembly proteins.
Yeo WS, Lee JH, Lee KC, Roe JH. | 01/21/2010 |