The Role of BAG3 Protein Interactions in Cardiomyopathies. | The Role of BAG3 Protein Interactions in Cardiomyopathies. Qu HQ, Wang JF, Rosa-Campos A, Hakonarson H, Feldman AM., Free PMC Article | 11/4/2024 |
Universal Adapter Protein Bag3 and Small Heat Shock Proteins. | Universal Adapter Protein Bag3 and Small Heat Shock Proteins. Zamotina MA, Muranova LK, Zabolotskii AI, Tyurin-Kuzmin PA, Kulebyakin KY, Gusev NB. | 10/28/2024 |
CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction. | CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction. Zhang C, Xu H, Tang Q, Duan Y, Xia H, Huang H, Ye D, Bi F., Free PMC Article | 10/18/2024 |
Functional analysis of a common BAG3 allele associated with protection from heart failure. | Functional analysis of a common BAG3 allele associated with protection from heart failure. Perez-Bermejo JA, Judge LM, Jensen CL, Wu K, Watry HL, Truong A, Ho JJ, Carter M, Runyon WV, Kaake RM, Pulido EH, Mandegar MA, Swaney DL, So PL, Krogan NJ, Conklin BR. | 10/7/2024 |
Acetylation-dependent deubiquitinase USP26 stabilizes BAG3 to promote breast cancer progression. | Acetylation-dependent deubiquitinase USP26 stabilizes BAG3 to promote breast cancer progression. Liu J, Zhai M, Chen Y, Wei Y, Li F, Chen Y, Duan B, Xing L, Du H, Jiang M, Li H, Ren G. | 08/1/2024 |
BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1. | BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1. Lin H, Sandkuhler S, Dunlea C, Rodwell-Bullock J, King DH, Johnson GVW., Free PMC Article | 03/11/2024 |
Distal hereditary motor neuronopathy as a new phenotype associated with variants in BAG3. | Distal hereditary motor neuronopathy as a new phenotype associated with variants in BAG3. de Fuenmayor-Fernández de la Hoz CP, Lupo V, Bermejo-Guerrero L, Martín-Jiménez P, Hernández-Laín A, Olivé M, Gallardo E, Esteban-Pérez J, Espinós C, Domínguez-González C. | 02/8/2024 |
Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants. | Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants. Martin TG, Pak H, Gerhard GS, Merali S, Merali C, Lemster B, Dubey P, McTiernan CF, Bristow MR, Feldman AM, Kirk JA., Free PMC Article | 01/3/2024 |
BAG3: Nature's Quintessential Multi-Functional Protein Functions as a Ubiquitous Intra-Cellular Glue. | BAG3: Nature's Quintessential Multi-Functional Protein Functions as a Ubiquitous Intra-Cellular Glue. Brenner CM, Choudhary M, McCormick MG, Cheung D, Landesberg GP, Wang JF, Song J, Martin TG, Cheung JY, Qu HQ, Hakonarson H, Feldman AM., Free PMC Article | 04/12/2023 |
MiR-135a-5p suppresses breast cancer cell proliferation, migration, and invasion by regulating BAG3. | MiR-135a-5p suppresses breast cancer cell proliferation, migration, and invasion by regulating BAG3. Zhang H, Wang M, Lang Z, Liu H, Liu J, Ma L., Free PMC Article | 10/22/2022 |
Unraveling the mystery: How bad is BAG3 in hematological malignancies? | Unraveling the mystery: How bad is BAG3 in hematological malignancies? Liu Q, Liu J, Huang X. | 10/15/2022 |
Therapeutic induction of Bcl2-associated athanogene 3-mediated autophagy in idiopathic pulmonary fibrosis. | Therapeutic induction of Bcl2-associated athanogene 3-mediated autophagy in idiopathic pulmonary fibrosis. Chillappagari S, Schwarz J, Kesireddy V, Knoell J, Korfei M, Hoetzenecker K, Schmitz ML, Behl C, Bellusci S, Guenther A, Mahavadi P., Free PMC Article | 07/30/2022 |
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis. | BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis. Lu X, Zhang J, Xue P, Wang Q, Wang X, Sun Y, Cui Z. | 07/9/2022 |
BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance. | BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance. Lin H, Tang M, Ji C, Girardi P, Cvetojevic G, Chen D, Koren SA, Johnson GVW., Free PMC Article | 06/25/2022 |
Metformin rescues muscle function in BAG3 myofibrillar myopathy models. | Metformin rescues muscle function in BAG3 myofibrillar myopathy models. Ruparelia AA, McKaige EA, Williams C, Schulze KE, Fuchs M, Oorschot V, Lacene E, Meregalli M, Lee C, Serrano RJ, Baxter EC, Monro K, Torrente Y, Ramm G, Stojkovic T, Lavoie JN, Bryson-Richardson RJ., Free PMC Article | 04/16/2022 |
Lutein induces an inhibitory effect on the malignant progression of pancreatic adenocarcinoma by targeting BAG3/cholesterol homeostasis. | Lutein induces an inhibitory effect on the malignant progression of pancreatic adenocarcinoma by targeting BAG3/cholesterol homeostasis. Han L, Song X. | 04/2/2022 |
BAG3 induces alpha-SMA expression in human fibroblasts and its over-expression correlates with poorer survival in fibrotic cancer patients. | BAG3 induces α-SMA expression in human fibroblasts and its over-expression correlates with poorer survival in fibrotic cancer patients. De Marco M, Del Papa N, Reppucci F, Iorio V, Basile A, Falco A, Iaccarino R, Brongo S, De Caro F, Capunzo M, Turco MC, Rosati A, Marzullo L., Free PMC Article | 03/19/2022 |
BAG3 is a negative regulator of ciliogenesis in glioblastoma and triple-negative breast cancer cells. | BAG3 is a negative regulator of ciliogenesis in glioblastoma and triple-negative breast cancer cells. Linder B, Klein C, Hoffmann ME, Bonn F, Dikic I, Kögel D. | 03/19/2022 |
Neurodegeneration and Astrogliosis in the Human CA1 Hippocampal Subfield Are Related to hsp90ab1 and bag3 in Alzheimer's Disease. | Neurodegeneration and Astrogliosis in the Human CA1 Hippocampal Subfield Are Related to hsp90ab1 and bag3 in Alzheimer's Disease. Gonzalez-Rodriguez M, Villar-Conde S, Astillero-Lopez V, Villanueva-Anguita P, Ubeda-Banon I, Flores-Cuadrado A, Martinez-Marcos A, Saiz-Sanchez D., Free PMC Article | 02/5/2022 |
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins. | PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins. Zhang C, Tang Q, Xia H, Xu H, Bi F. | 01/15/2022 |
An emerging role for BAG3 in gynaecological malignancies. | An emerging role for BAG3 in gynaecological malignancies. De Marco M, Falco A, Iaccarino R, Raffone A, Mollo A, Guida M, Rosati A, Chetta M, Genovese G, De Caro F, Capunzo M, Turco MC, Uversky VN, Marzullo L., Free PMC Article | 12/18/2021 |
CDK1-Mediated Phosphorylation of BAG3 Promotes Mitotic Cell Shape Remodeling and the Molecular Assembly of Mitotic p62 Bodies. | CDK1-Mediated Phosphorylation of BAG3 Promotes Mitotic Cell Shape Remodeling and the Molecular Assembly of Mitotic p62 Bodies. Luthold C, Lambert H, Guilbert SM, Rodrigue MA, Fuchs M, Varlet AA, Fradet-Turcotte A, Lavoie JN., Free PMC Article | 12/11/2021 |
BAG3 epigenetically regulates GALNT10 expression via WDR5 and facilitates the stem cell-like properties of platin-resistant ovarian cancer cells. | BAG3 epigenetically regulates GALNT10 expression via WDR5 and facilitates the stem cell-like properties of platin-resistant ovarian cancer cells. Zhao FY, Zhang Q, Wang JM, Jiang JY, Huyan LY, Liu BQ, Yan J, Li C, Wang HQ. | 12/4/2021 |
Advances in the role and mechanism of BAG3 in dilated cardiomyopathy. | Advances in the role and mechanism of BAG3 in dilated cardiomyopathy. Liu L, Sun K, Zhang X, Tang Y, Xu D. | 10/30/2021 |
Novel BAG3 Variants in African American Patients With Cardiomyopathy: Reduced beta-Adrenergic Responsiveness in Excitation-Contraction. | Novel BAG3 Variants in African American Patients With Cardiomyopathy: Reduced β-Adrenergic Responsiveness in Excitation-Contraction. Feldman AM, Gordon J, Wang J, Song J, Zhang XQ, Myers VD, Tomar D, Gerhard GS, Khalili K, Cheung JY., Free PMC Article | 09/25/2021 |