| AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction. | AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction.
Qasim H, Rajaei M, Xu Y, Reyes-Alcaraz A, Abdelnasser HY, Stewart MD, Lahiri SK, Wehrens XHT, McConnell BK., Free PMC Article | 05/1/2024 |
| AKAP12 and IGFBP4 Are Prognostic Factors for Chronic Lymphocytic Leukemia. | AKAP12 and IGFBP4 Are Prognostic Factors for Chronic Lymphocytic Leukemia.
Shi Y, Xu X, He Z, Tao H, Chen Y, Zhang L, Tao S, Ding B, Wang C, Yu L. | 01/4/2024 |
| AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway. | AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Li X, Dong H, Zheng Y, Ding S, Li Y, Li H, Huang H, Zhong C, Xie T, Xu Y. | 12/6/2023 |
| AKAP12 promotes cancer stem cell-like phenotypes and activates STAT3 in colorectal cancer. | AKAP12 promotes cancer stem cell-like phenotypes and activates STAT3 in colorectal cancer.
Li K, Wu X, Li Y, Hu TT, Wang W, Gonzalez FJ, Liu W. | 09/25/2023 |
| Circ_0001777 Affects Triple-negative Breast Cancer Progression Through the miR-95-3p/AKAP12 Axis. | Circ_0001777 Affects Triple-negative Breast Cancer Progression Through the miR-95-3p/AKAP12 Axis.
Chen Z, Gong X, Cheng C, Fu Y, Wu W, Luo Z. | 02/11/2023 |
| HDAC6-dependent deacetylation of AKAP12 dictates its ubiquitination and promotes colon cancer metastasis. | HDAC6-dependent deacetylation of AKAP12 dictates its ubiquitination and promotes colon cancer metastasis.
Deng Y, Gao J, Xu G, Yao Y, Sun Y, Shi Y, Hao X, Niu L, Li H. | 10/22/2022 |
| Comprehensive Analysis of the Immune Implication of AKAP12 in Stomach Adenocarcinoma. | Comprehensive Analysis of the Immune Implication of AKAP12 in Stomach Adenocarcinoma.
Xu Z, Xiang L, Peng L, Gu H, Wang Y., Free PMC Article | 10/1/2022 |
| Physiologic and pathophysiologic roles of AKAP12. | Physiologic and pathophysiologic roles of AKAP12.
Li H., Free PMC Article | 07/16/2022 |
| Overexpression of miR-146a promotes cell proliferation and migration in a model of diabetic foot ulcers by regulating the AKAP12 axis. | Overexpression of miR-146a promotes cell proliferation and migration in a model of diabetic foot ulcers by regulating the AKAP12 axis.
Zhang HC, Wen T, Cai YZ. | 04/9/2022 |
| AKAP12/Gravin is over-expressed in patients with ulcerative colitis. | AKAP12/Gravin is over-expressed in patients with ulcerative colitis.
Fonseca-Camarillo G, Furuzawa-Carballeda J, Priego-Ranero ÁA, Zúñiga RB, Martínez-Benítez B, Yamamoto-Furusho JK. | 02/5/2022 |
| Upregulated PPARG2 facilitates interaction with demethylated AKAP12 gene promoter and suppresses proliferation in prostate cancer. | Upregulated PPARG2 facilitates interaction with demethylated AKAP12 gene promoter and suppresses proliferation in prostate cancer.
Li F, Lu T, Liu D, Zhang C, Zhang Y, Dong F., Free PMC Article | 09/25/2021 |
| Downregulation of microRNA-144 inhibits proliferation and promotes the apoptosis of myelodysplastic syndrome cells through the activation of the AKAP12-dependent ERK1/2 signaling pathway. | Downregulation of microRNA-144 inhibits proliferation and promotes the apoptosis of myelodysplastic syndrome cells through the activation of the AKAP12-dependent ERK1/2 signaling pathway.
Qian W, Jin F, Zhao Y, Chen Y, Ge L, Liu L, Yang M. | 06/12/2021 |
| Gravin-associated kinase signaling networks coordinate gamma-tubulin organization at mitotic spindle poles. | Gravin-associated kinase signaling networks coordinate γ-tubulin organization at mitotic spindle poles.
Bucko PJ, Garcia I, Manocha R, Bhat A, Wordeman L, Scott JD., Free PMC Article | 02/6/2021 |
| MicroRNA-1251-5p promotes tumor growth and metastasis of hepatocellular carcinoma by targeting AKAP12. | MicroRNA-1251-5p promotes tumor growth and metastasis of hepatocellular carcinoma by targeting AKAP12.
Han S, Wang L, Sun L, Wang Y, Yao B, Chen T, Liu R, Liu Q. | 10/3/2020 |
| LINC00163 expression in gastric cancer can sponge miR-183 to promote AKAP12.AKAP12 was weakly expressed in gastric cancer and suppressed invasion and metastasis in the gastric cancer cells. | LINC00163 inhibits the invasion and metastasis of gastric cancer cells as a ceRNA by sponging miR-183 to regulate the expression of AKAP12.
Zhang J, Piao HY, Guo S, Wang Y, Zhang T, Zheng ZC, Zhao Y. | 07/4/2020 |
| Sequence variation at the MTHFD1L-AKAP12 and FOPNL loci does not influence multiple myeloma survival in Sweden.( | Sequence variation at the MTHFD1L-AKAP12 and FOPNL loci does not influence multiple myeloma survival in Sweden.
Ali M, Lemonakis K, Wihlborg AK, Veskovski L, Turesson I, Mellqvist UH, Gullberg U, Hansson M, Nilsson B., Free PMC Article | 05/2/2020 |
| This study demonstrates that AKAP12-mediated regulation of portal fibroblasts and liver sinusoidal endothelial cells has a central role in resolving hepatic fibrosis. | Altered AKAP12 expression in portal fibroblasts and liver sinusoids mediates transition from hepatic fibrogenesis to fibrosis resolution.
Lee HS, Choi J, Son T, Wee HJ, Bae SJ, Seo JH, Park JH, Ryu SH, Lee D, Jang MK, Yu E, Chung YH, Kim KW., Free PMC Article | 04/25/2020 |
| Aldosterone impairs mitochondrial function in human cardiac fibroblasts via AKAP12. | Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12.
Ibarrola J, Sadaba R, Martinez-Martinez E, Garcia-Peña A, Arrieta V, Alvarez V, Fernández-Celis A, Gainza A, Cachofeiro V, Santamaria E, Fernandez-Irigoyen J, Jaisser F, Lopez-Andres N., Free PMC Article | 10/12/2019 |
| Disruption of a Gravin-PLK1 interface leads to inappropriate PLK1 activity contributing to chromosome segregation errors, formation of micronuclei, and subsequent DNA damage. | Gravin regulates centrosome function through PLK1.
Colicino EG, Garrastegui AM, Freshour J, Santra P, Post DE, Kotula L, Hehnly H., Free PMC Article | 02/2/2019 |
| the findings in this study suggest that AKAP12 is a potential metastasis suppressor in breast cancer. | A-kinase anchor protein 12 (AKAP12) inhibits cell migration in breast cancer.
Soh RYZ, Lim JP, Samy RP, Chua PJ, Bay BH. | 01/5/2019 |
| Low AKAP12 expression is associated with high-grade meningiomas. | Kinome and phosphoproteome of high-grade meningiomas reveal AKAP12 as a central regulator of aggressiveness and its possible role in progression.
Parada CA, Osbun J, Kaur S, Yakkioui Y, Shi M, Pan C, Busald T, Karasozen Y, Gonzalez-Cuyar LF, Rostomily R, Zhang J, Ferreira M Jr., Free PMC Article | 12/22/2018 |
| these findings indicate that AKAP12 may be a potential prognostic predictor and therapeutic target for the treatment of colorectal cancer in combination with HDAC3 | Upregulation of AKAP12 with HDAC3 depletion suppresses the progression and migration of colorectal cancer.
He P, Li K, Li SB, Hu TT, Guan M, Sun FY, Liu WW. | 08/25/2018 |
| There is a positive association between the expression of AKAP12 and Semaphorin 3F in prostate cancer, suggesting that the activation of Semaphorin 3F by AKAP12 may be involved in prostate cancer progression and metastasis. | SSeCKS/AKAP12 induces repulsion between human prostate cancer and microvessel endothelial cells through the activation of Semaphorin 3F.
Xie W, Su W, Zhang L, Shang Q, Su B. | 08/12/2017 |
| the AKAP12a promoter shows high DNA methylation levels in juvenile myelomonocytic leukemia, which go along with reduced AKAP12a mRNA expression levels | Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia.
Wilhelm T, Lipka DB, Witte T, Wierzbinska JA, Fluhr S, Helf M, Mücke O, Claus R, Konermann C, Nöllke P, Niemeyer CM, Flotho C, Plass C., Free PMC Article | 12/17/2016 |
| MiR-103 regulates hepatocellular carcinoma growth by targeting AKAP12 | MiR-103 regulates hepatocellular carcinoma growth by targeting AKAP12.
Xia W, Ni J, Zhuang J, Qian L, Wang P, Wang J. | 10/22/2016 |