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    Wwtr1 WW domain containing transcription regulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 97064, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Taz/Tead1 Promotes Alternative Macrophage Activation and Kidney Fibrosis via Transcriptional Upregulation of Smad3.

    Taz/Tead1 Promotes Alternative Macrophage Activation and Kidney Fibrosis via Transcriptional Upregulation of Smad3.
    Ren Y, Zhou L, Li X, Zhu X, Zhang Z, Sun X, Xue X, Dai C., Free PMC Article

    09/16/2024
    Analyzing embryo dormancy at single-cell resolution reveals dynamic transcriptional responses and activation of integrin-Yap/Taz prosurvival signaling.

    Analyzing embryo dormancy at single-cell resolution reveals dynamic transcriptional responses and activation of integrin-Yap/Taz prosurvival signaling.
    Chen R, Fan R, Chen F, Govindasamy N, Brinkmann H, Stehling M, Adams RH, Jeong HW, Bedzhov I.

    09/16/2024
    YAP and TAZ differentially regulate postnatal cortical progenitor proliferation and astrocyte differentiation.

    YAP and TAZ differentially regulate postnatal cortical progenitor proliferation and astrocyte differentiation.
    Chen J, Tsai YH, Linden AK, Kessler JA, Peng CY.

    07/24/2024
    Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation.

    Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation.
    Song Y, Na H, Lee SE, Kim YM, Moon J, Nam TW, Ji Y, Jin Y, Park JH, Cho SC, Lee J, Hwang D, Ha SJ, Park HW, Kim JB, Lee HW., Free PMC Article

    07/16/2024
    TAZ deficiency impairs the autophagy-lysosomal pathway through NRF2 dysregulation and lysosomal dysfunction.

    TAZ deficiency impairs the autophagy-lysosomal pathway through NRF2 dysregulation and lysosomal dysfunction.
    Kim HK, Jeong H, Jeong MG, Won HY, Lee G, Bae SH, Nam M, Lee SH, Hwang GS, Hwang ES., Free PMC Article

    06/13/2024
    YAP and TAZ differentially regulate postnatal cortical progenitor proliferation and astrocyte differentiation.

    YAP and TAZ differentially regulate postnatal cortical progenitor proliferation and astrocyte differentiation.
    Chen J, Tsai YH, Linden AK, Kessler JA, Peng CY.

    06/6/2024
    Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology.

    Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology.
    Li H, Kuhn M, Kelly RA, Singh A, Palanivel KK, Salama I, De Ieso ML, Stamer WD, Ganapathy PS, Herberg S.,

    02/13/2024
    Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice.

    Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice.
    Behrmann A, Zhong D, Li L, Xie S, Mead M, Sabaeifard P, Goodarzi M, Lemoff A, Kozlitina J, Towler DA.,

    01/17/2024
    TAZ stimulates exercise-induced muscle satellite cell activation via Pard3-p38 MAPK-TAZ signalling axis.

    TAZ stimulates exercise-induced muscle satellite cell activation via Pard3-p38 MAPK-TAZ signalling axis.
    Kim KM, Yoo GD, Heo W, Oh HT, Park J, Shin S, Do Y, Jeong MG, Hwang ES, Hong JH., Free PMC Article

    01/6/2024
    TAZ facilitates breast tumor growth by promoting an immune-suppressive tumor microenvironment.

    TAZ facilitates breast tumor growth by promoting an immune-suppressive tumor microenvironment.
    Gershoni A, Hassin O, Nataraj NB, Baruch S, Avioz-Seligman A, Pirona AC, Fellus-Alyagor L, Meir Salame T, Mukherjee S, Mallel G, Yarden Y, Aylon Y, Oren M., Free PMC Article

    12/21/2023
    Genetic interactions between polycystin-1 and Wwtr1 in osteoblasts define a novel mechanosensing mechanism regulating bone formation in mice.

    Genetic interactions between polycystin-1 and Wwtr1 in osteoblasts define a novel mechanosensing mechanism regulating bone formation in mice.
    Xiao Z, Cao L, Smith MD, Li H, Li W, Smith JC, Quarles LD., Free PMC Article

    11/15/2023
    Regulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity in mouse ovaries.

    Regulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity in mouse ovaries.
    Devos M, Dias Nunes J, Donfack Jiatsa N, Demeestere I., Free PMC Article

    09/23/2023
    Vascular smooth muscle-specific YAP/TAZ deletion triggers aneurysm development in mouse aorta.

    Vascular smooth muscle-specific YAP/TAZ deletion triggers aneurysm development in mouse aorta.
    Arévalo Martínez M, Ritsvall O, Bastrup JA, Celik S, Jakobsson G, Daoud F, Winqvist C, Aspberg A, Rippe C, Maegdefessel L, Schiopu A, Jepps TA, Holmberg J, Swärd K, Albinsson S., Free PMC Article

    09/13/2023
    Loss of TAZ after YAP deletion severely impairs foregut development and worsens cholestatic hepatocellular injury.

    Loss of TAZ after YAP deletion severely impairs foregut development and worsens cholestatic hepatocellular injury.
    Gabdulkhakova A, Krutsenko Y, Zhu J, Liu S, Poddar M, Singh S, Ma X, Nejak-Bowen K, Monga SPS, Molina LM., Free PMC Article

    08/11/2023
    Emerging Roles of YAP/TAZ in Tooth and Surrounding: from Development to Regeneration.

    Emerging Roles of YAP/TAZ in Tooth and Surrounding: from Development to Regeneration.
    Yang S, Huang F, Zhang F, Sheng X, Fan W, Dissanayaka WL.

    08/3/2023
    A YAP/TAZ-CD54 axis is required for CXCR2-CD44- tumor-specific neutrophils to suppress gastric cancer.

    A YAP/TAZ-CD54 axis is required for CXCR2-CD44- tumor-specific neutrophils to suppress gastric cancer.
    Nie P, Zhang W, Meng Y, Lin M, Guo F, Zhang H, Tong Z, Wang M, Chen F, An L, Tang Y, Han Y, Yu R, Wang W, Xu Y, Wei L, Zhou Z, Jiao S., Free PMC Article

    06/30/2023
    Denervation Drives YAP/TAZ Activation in Muscular Fibro/Adipogenic Progenitors.

    Denervation Drives YAP/TAZ Activation in Muscular Fibro/Adipogenic Progenitors.
    Gallardo FS, Córdova-Casanova A, Bock-Pereda A, Rebolledo DL, Ravasio A, Casar JC, Brandan E., Free PMC Article

    03/31/2023
    Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney.

    Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney.
    Drake KA, Chaney C, Patel M, Das A, Bittencourt J, Cohn M, Carroll TJ., Free PMC Article

    01/28/2023
    Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism.

    Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism.
    Shen H, Zhang Y, Kramer ED, Katsuta E, Wan Y, Chen Y, Wang J, Zhang Y, Matsuzaki J, Frangou C, Abrams SI, Zhang J., Free PMC Article

    01/28/2023
    CD133-Src-TAZ signaling stimulates ductal fibrosis following DDC diet-induced liver injury.

    CD133-Src-TAZ signaling stimulates ductal fibrosis following DDC diet-induced liver injury.
    Oh HT, Heo W, Yoo GD, Kim KM, Hwang JH, Hwang ES, Ko J, Ko YG, Hong JH.

    12/24/2022
    Role of smooth muscle YAP and TAZ in protection against phenotypic modulation, inflammation, and aneurysm development.

    Role of smooth muscle YAP and TAZ in protection against phenotypic modulation, inflammation, and aneurysm development.
    Daoud F, Arévalo Martínez M, Holst J, Holmberg J, Albinsson S, Swärd K.

    12/17/2022
    Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers.

    Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers.
    Soyama H, Nishio M, Otani J, Sakuma T, Takao S, Hara S, Masuda T, Mimori K, Toyokuni S, Lydon JP, Nakao K, Nishina H, Fukumoto T, Maehama T, Suzuki A., Free PMC Article

    07/30/2022
    TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis.

    TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis.
    Wang X, Zeldin S, Shi H, Zhu C, Saito Y, Corey KE, Osganian SA, Remotti HE, Verna EC, Pajvani UB, Schwabe RF, Tabas I., Free PMC Article

    07/23/2022
    YAP and TAZ in Vascular Smooth Muscle Confer Protection Against Hypertensive Vasculopathy.

    YAP and TAZ in Vascular Smooth Muscle Confer Protection Against Hypertensive Vasculopathy.
    Daoud F, Arévalo Martinez M, Holmberg J, Alajbegovic A, Ali N, Rippe C, Swärd K, Albinsson S., Free PMC Article

    07/9/2022
    Loss of Yap/Taz in cardiac fibroblasts attenuates adverse remodelling and improves cardiac function.

    Loss of Yap/Taz in cardiac fibroblasts attenuates adverse remodelling and improves cardiac function.
    Mia MM, Cibi DM, Ghani SABA, Singh A, Tee N, Sivakumar V, Bogireddi H, Cook SA, Mao J, Singh MK.

    07/2/2022
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