| The influence of NOS1AP gene polymorphisms and childhood abuse on antisocial personality disorder in Chinese male violent inmates. | The influence of NOS1AP gene polymorphisms and childhood abuse on antisocial personality disorder in Chinese male violent inmates.
Li J, Ouyang L, Liu X, Wang Q, Min Z, Liu G, Zhong Y, Zhang N, Wang C, Liu N. | 05/10/2023 |
| Influence of NOS1AP Risk Variants on the Corrected QT (QTc) Interval in the Pharmacotherapy of Schizophrenia. | Influence of NOS1AP Risk Variants on the Corrected QT (QTc) Interval in the Pharmacotherapy of Schizophrenia.
Esen-Sehir D, Kopf J, Hägele S, Plichta MM, Reif A, Freudenberg F. | 09/24/2022 |
| Evaluating Common NOS1AP Variants in Patients with Implantable Cardioverter Defibrillators for Secondary Prevention : Evaluating SNPs in NOS1AP. | Evaluating Common NOS1AP Variants in Patients with Implantable Cardioverter Defibrillators for Secondary Prevention : Evaluating SNPs in NOS1AP.
Zang X, Zhang S, Li S, Wang X, Song W, Chen K, Ma J, Tu X, Xia Y, Zhao Y, Gao C. | 09/24/2022 |
| Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice. | Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice.
Majmundar AJ, Buerger F, Forbes TA, Klämbt V, Schneider R, Deutsch K, Kitzler TM, Howden SE, Scurr M, Tan KS, Krzeminski M, Widmeier E, Braun DA, Lai E, Ullah I, Amar A, Kolb A, Eddy K, Chen CH, Salmanullah D, Dai R, Nakayama M, Ottlewski I, Kolvenbach CM, Onuchic-Whitford AC, Mao Y, Mann N, Nabhan MM, Rosen S, Forman-Kay JD, Soliman NA, Heilos A, Kain R, Aufricht C, Mane S, Lifton RP, Shril S, Little MH, Hildebrandt F., Free PMC Article | 04/30/2022 |
| A NOS1AP gene variant is associated with a paradoxical increase of the QT-interval shortening effect of digoxin. | A NOS1AP gene variant is associated with a paradoxical increase of the QT-interval shortening effect of digoxin.
Soroush N, Aarnoudse AJ, Kavousi M, Kors JA, Ikram MA, Newton-Cheh C, Ahmadizar F, Stricker BH. | 03/12/2022 |
| PPARD rs2016520 (T/C) and NOS1AP rs12742393 (A/C) polymorphisms affect therapeutic efficacy of nateglinide in Chinese patients with type 2 diabetes mellitus. | PPARD rs2016520 (T/C) and NOS1AP rs12742393 (A/C) polymorphisms affect therapeutic efficacy of nateglinide in Chinese patients with type 2 diabetes mellitus.
Wang T, Song JF, Zhou XY, Li CL, Yin XX, Lu Q., Free PMC Article | 03/5/2022 |
| NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis. | NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis.
Ronchi C, Bernardi J, Mura M, Stefanello M, Badone B, Rocchetti M, Crotti L, Brink P, Schwartz PJ, Gnecchi M, Zaza A., Free PMC Article | 12/4/2021 |
| Effects of interaction of NOS1AP gene polymorphisms and childhood abuse on paranoid personality disorder features among male violent offenders in China. | Effects of interaction of NOS1AP gene polymorphisms and childhood abuse on paranoid personality disorder features among male violent offenders in China.
Wang Q, Liu G, Li J, Zhang M, Chen H, Chen C, Wang C, Liu N, Zhang N. | 05/15/2021 |
| Differentiated PDGFRalpha-Positive Cells: A Novel In-Vitro Model for Functional Studies of Neuronal Nitric Oxide Synthase. | Differentiated PDGFRα-Positive Cells: A Novel In-Vitro Model for Functional Studies of Neuronal Nitric Oxide Synthase.
Mussa BM, Khan AA, Srivastava A, Abdallah SH., Free PMC Article | 05/15/2021 |
| Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death. | Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death.
Mitchell RN, Ashar FN, Jarvelin MR, Froguel P, Sotoodehnia N, Brody JA, Sebert S, Huikuri H, Rioux J, Goyette P, Newcomb CE, Junttila MJ, Arking DE., Free PMC Article | 01/9/2021 |
| CAPON Is a Critical Protein in Synaptic Molecular Networks in the Prefrontal Cortex of Mood Disorder Patients and Contributes to Depression-Like Behavior in a Mouse Model. | CAPON Is a Critical Protein in Synaptic Molecular Networks in the Prefrontal Cortex of Mood Disorder Patients and Contributes to Depression-Like Behavior in a Mouse Model.
Gao S, Zhang T, Jin L, Liang D, Fan G, Song Y, Lucassen PJ, Yu R, Swaab DF. | 10/10/2020 |
| the minor allele of rs10494366 may have an impact on the QT interval in women or diabetes mellitus patients and may have a potential role in sudden death in the Caucasian population(Meta-Analysis) | Systematic Meta-Analysis of the Association Between a Common NOS1AP Genetic Polymorphism, the QTc Interval, and Sudden Death.
Zang X, Li S, Zhao Y, Chen K, Wang X, Song W, Ma J, Tu X, Xia Y, Zhang S, Gao C. | 12/21/2019 |
| The effects of CAPON-L overexpression on glioma cell proliferation are dependent on the AKT/mTOR/P53 activity. The overexpression of CAPON inhibits U251 cell proliferation through the AKT/mTOR signaling pathway, while overexpressing CAPON-L promoted U87 cell proliferation, possibly through down-regulating the P53 level. | Effects of Long Form of CAPON Overexpression on Glioma Cell Proliferation are Dependent on AKT/mTOR/P53 Signaling.
Liang D, Song Y, Fan G, Ji D, Zhang T, Nie E, Liu X, Liang J, Yu R, Gao S., Free PMC Article | 12/7/2019 |
| Genetic variation rs12143842 in NOS1AP gene is associated with idiopathic ventricular tachycardia. | The genetic variation rs12143842 in NOS1AP increases idiopathic ventricular tachycardia risk in Chinese Han populations.
Zhang R, Chen F, Yu H, Gao L, Yin X, Dong Y, Yang Y, Xia Y., Free PMC Article | 04/20/2019 |
| Findings showed that NOS1AP (rs348624, rs12742393 and rs1415263), DISC1 (rs821633 and rs1000731), DAOA (rs2391191) and GSK3B (rs6438552) SNPs had no association with development of early-onset schizophrenia; however, our finding suggested statistically significant role of the interaction of NOS1AP, DISC1, DAOA and GSK3B polymorphisms in schizophrenia susceptibility. | The interaction of NOS1AP, DISC1, DAOA, and GSK3B confers susceptibility of early-onset schizophrenia in Chinese Han population.
Hu G, Yang C, Zhao L, Fan Y, Lv Q, Zhao J, Zhu M, Guo X, Bao C, Xu A, Jie Y, Jiang Y, Zhang C, Yu S, Wang Z, Li Z, Yi Z. | 07/7/2018 |
| Novel Hispanic/Latino-specific Single Nucleotide Polymorphism at NOS1AP implicate gene regulatory dysfunction in QT prolongation. | Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations.
Avery CL, Wassel CL, Richard MA, Highland HM, Bien S, Zubair N, Soliman EZ, Fornage M, Bielinski SJ, Tao R, Seyerle AA, Shah SJ, Lloyd-Jones DM, Buyske S, Rotter JI, Post WS, Rich SS, Hindorff LA, Jeff JM, Shohet RV, Sotoodehnia N, Lin DY, Whitsel EA, Peters U, Haiman CA, Crawford DC, Kooperberg C, North KE., Free PMC Article | 01/27/2018 |
| If the expression of Capon is decreased, myeloma cells are adhered to fibronectin or bone marrow stromal cells (bone marrow mesenchymal stem cells). In addition, the sensitivity of the cell line to chemotherapeutic agents was reduced after silencing Capon in the myeloma cell line which was adhered to bone marrow mesenchymal stem cells. | The role of Capon in multiple myeloma.
Shen Y, Liu H, Gu S, Wei Z, Liu H. | 07/29/2017 |
| sex was identified as a moderator of the association between NOS1AP sequence variants and QTc prolongation in two long QT syndrome founder populations | Sex is a moderator of the association between NOS1AP sequence variants and QTc in two long QT syndrome founder populations: a pedigree-based measured genotype association analysis.
Winbo A, Stattin EL, Westin IM, Norberg A, Persson J, Jensen SM, Rydberg A., Free PMC Article | 07/29/2017 |
| Association between NOS1AP and PTSD severity, depression, anxiety, and stress was found. NOS1AP was associated with resilience. | Nitric oxide pathway genes (NOS1AP and NOS1) are involved in PTSD severity, depression, anxiety, stress and resilience.
Bruenig D, Morris CP, Mehta D, Harvey W, Lawford B, Young RM, Voisey J. | 06/24/2017 |
| gender modulated the interaction between NOS1AP promoter DNA methylation in intracranial aneurysm and brain arteriovenous malformation BAVM patients | Sex-dichotomous effects of NOS1AP promoter DNA methylation on intracranial aneurysm and brain arteriovenous malformation.
Wang Z, Zhao J, Sun J, Nie S, Li K, Gao F, Zhang T, Duan S, Di Y, Huang Y, Gao X. | 06/24/2017 |
| results hint towards an involvement of NOS-I/NOS1AP interaction in the regulation of dendritic spine plasticity | Interaction of NOS1AP with the NOS-I PDZ domain: Implications for schizophrenia-related alterations in dendritic morphology.
Candemir E, Kollert L, Weißflog L, Geis M, Müller A, Post AM, O'Leary A, Harro J, Reif A, Freudenberg F. | 05/7/2017 |
| Results from genome-wide DNA methylation, functional network analysis and pyrosequencing, show selective CpG sites (NOS1AP, BID, and GABRB1) differentially methylated in smokers and chronic obstructive pulmonary disease patients compared to nonsmokers. | DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD.
Sundar IK, Yin Q, Baier BS, Yan L, Mazur W, Li D, Susiarjo M, Rahman I., Free PMC Article | 04/22/2017 |
| Data indicate that overexpression of nitric oxide synthase 1 adaptor protein short form (CAPON-S) led to the inactivation of the proto-oncogene protein Akt (Akt) signaling pathway. | Low Expression of CAPON in Glioma Contributes to Cell Proliferation via the Akt Signaling Pathway.
Gao S, Wang J, Zhang T, Liu G, Jin L, Ji D, Wang P, Meng Q, Zhu Y, Yu R., Free PMC Article | 04/15/2017 |
| SNPs in the NOS1AP gene influence QTc interval duration but we have not demonstrated a direct association with the risk of sudden cardiac death | NOS1AP Polymorphisms Modify QTc Interval Duration But Not Cardiac Arrest Risk in Hypertrophic Cardiomyopathy.
Earle N, Ingles J, Bagnall RD, Gray B, Crawford J, Smith W, Shelling AN, Love DR, Semsarian C, Skinner JR. | 10/8/2016 |
| Results suggest that NOS1AP variants are associated with various forms of depression in schizophrenia and are more prevalent in males. | Association of NOS1AP variants and depression phenotypes in schizophrenia.
Cheah SY, Lawford BR, Young RM, Morris CP, Voisey J. | 06/11/2016 |