| RIPOR2 Expression Decreased by HPV-16 E6 and E7 Oncoproteins: An Opportunity in the Search for Prognostic Biomarkers in Cervical Cancer. | RIPOR2 Expression Decreased by HPV-16 E6 and E7 Oncoproteins: An Opportunity in the Search for Prognostic Biomarkers in Cervical Cancer.
Olmedo-Nieva L, Muñoz-Bello JO, Martínez-Ramírez I, Martínez-Gutiérrez AD, Ortiz-Pedraza Y, González-Espinosa C, Madrid-Marina V, Torres-Poveda K, Bahena-Roman M, Lizano M., Free PMC Article | 12/31/2022 |
| this is the first study to explore and validate the relationships between seven SNPs in the FAM65B, AGBL4, and CUX2 genes and ATDH in a Chinese population. On the basis of this case-control study, SNP rs10946737 in FAM65B may be associated with susceptibility to ATDH in Chinese Han anti-TB treatment patients. | Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population.
Pan H, Yang M, Lu L, Tao B, He X, Chen H, Yi H, Tang S. | 02/22/2020 |
| results show that Fam65b expression and phosphorylation can finely tune the amount of active RhoA in order to favor optimal T lymphocyte motility. | Fam65b Phosphorylation Relieves Tonic RhoA Inhibition During T Cell Migration.
Megrelis L, El Ghoul E, Moalli F, Versapuech M, Cassim S, Ruef N, Stein JV, Mangeney M, Delon J., Free PMC Article | 09/28/2019 |
| FAM65B has a role in controlling proliferation of transformed and primary T cells | FAM65B controls the proliferation of transformed and primary T cells.
Froehlich J, Versapuech M, Megrelis L, Largeteau Q, Meunier S, Tanchot C, Bismuth G, Delon J, Mangeney M., Free PMC Article | 04/21/2018 |
| Mouse Ripor2 forms ring-like structures at the base of stereocilia and interacts with RhoC | Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.
Zhao B, Wu Z, Müller U., Free PMC Article | 12/11/2017 |
| In our analyses of the DYX2 locus, we observed associations of KIAA0319, ACOT13, and FAM65B with developing cortical thickness and/or functional anisotropy. | Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children.
Eicher JD, Montgomery AM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst T, Frazier J, Kaufmann WE, Keating B, Kenet T, Kennedy D, Mostofsky S, Murray SS, Sowell ER, Bartsch H, Kuperman JM, Brown TT, Hagler DJ Jr, Dale AM, Jernigan TL, Gruen JR, Pediatric Imaging Neurocognition Genetics Study., Free PMC Article | 12/17/2016 |
| These data together elucidate a mechanism for RHOA and pMLC polarization in stimulated neutrophils through direct inhibition of RHOA by FAM65B at the leading edge. | Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils.
Gao K, Tang W, Li Y, Zhang P, Wang D, Yu L, Wang C, Wu D., Free PMC Article | 12/26/2015 |
| Fam65b expression is necessary for the complex to form. | Fam65b is important for formation of the HDAC6-dysferlin protein complex during myogenic cell differentiation.
Balasubramanian A, Kawahara G, Gupta VA, Rozkalne A, Beauvais A, Kunkel LM, Gussoni E., Free PMC Article | 09/27/2014 |
| show that wild-type Fam65b is expressed during embryonic and postnatal development stages in murine cochlea, and that the protein localizes to the plasma membranes of the stereocilia of inner and outer hair cells of the inner ear | FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing.
Diaz-Horta O, Subasioglu-Uzak A, Grati M, DeSmidt A, Foster J 2nd, Cao L, Bademci G, Tokgoz-Yilmaz S, Duman D, Cengiz FB, Abad C, Mittal R, Blanton S, Liu XZ, Farooq A, Walz K, Lu Z, Tekin M., Free PMC Article | 09/20/2014 |
| PC3 tumors are sustained by a small number of tumor-initiating cells with stem-like characteristics, including strong self-renewal and pro-angiogenic capability and marked by the expression pattern FAM65Bhigh/MFI2low/LEF1low. | PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis.
Zhang K, Waxman DJ., Free PMC Article | 03/26/2011 |
| C6ORF32 is a novel protein likely to play multiple functions, including promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation | C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodia.
Yoon S, Molloy MJ, Wu MP, Cowan DB, Gussoni E., Free PMC Article | 01/21/2010 |