HAI-1 is required for the novel role of FGFBP1 in maintenance of cell morphology and F-actin rearrangement in human keratinocytes. | HAI-1 is required for the novel role of FGFBP1 in maintenance of cell morphology and F-actin rearrangement in human keratinocytes. Lu DD, Huang N, Li SA, Fang JR, Lai CH, Wang JK, Chan KS, Johnson MD, Lin CY. | 06/28/2023 |
Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. | Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. Chen X, Miao M, Zhou M, Chen J, Li D, Zhang L, Sun A, Guan M, Wang Z, Liu P, Zhang S, Zha X, Fan X., Free PMC Article | 01/29/2022 |
The Expression and Prognostic Value of FGF2, FGFR3, and FGFBP1 in Esophageal Squamous Cell Carcinoma. | The Expression and Prognostic Value of FGF2, FGFR3, and FGFBP1 in Esophageal Squamous Cell Carcinoma. Zhang W, Zhou Y, Li C, Xu S, Li M, Liu W, Ma Y, Wang H., Free PMC Article | 08/28/2021 |
FGFBP1-mediated crosstalk between fibroblasts and pancreatic cancer cells via FGF22/FGFR2 promotes invasion and metastasis of pancreatic cancer. | FGFBP1-mediated crosstalk between fibroblasts and pancreatic cancer cells via FGF22/FGFR2 promotes invasion and metastasis of pancreatic cancer. Zhang Z, Qin Y, Ji S, Xu W, Liu M, Hu Q, Ye Z, Fan G, Yu X, Liu W, Xu X. | 08/7/2021 |
These findings indicate that the miR-146a-CREB3L1-FGFBP1 signaling axis plays an important role in the regulation of angiogenesis in human umbilical vein endothelial cells. | Up-regulation of FGFBP1 signaling contributes to miR-146a-induced angiogenesis in human umbilical vein endothelial cells. Zhu HY, Bai WD, Liu JQ, Zheng Z, Guan H, Zhou Q, Su LL, Xie ST, Wang YC, Li J, Li N, Zhang YJ, Wang HT, Hu DH., Free PMC Article | 01/20/2018 |
Genetic polymorphism in the human FGFBP1 gene was associated with higher gene expression and an increased risk of familial Hypertension. | Blood Pressure Control by a Secreted FGFBP1 (Fibroblast Growth Factor-Binding Protein). Tassi E, Lai EY, Li L, Solis G, Chen Y, Kietzman WE, Ray PE, Riegel AT, Welch WJ, Wilcox CS, Wellstein A., Free PMC Article | 12/23/2017 |
Up-regulated Sox12 induced by FoxQ1 promotes hepatocellular carcinoma invasion and metastasis by transactivating Twist1 and FGFBP1 expression. | Sox12, a direct target of FoxQ1, promotes hepatocellular carcinoma metastasis through up-regulating Twist1 and FGFBP1. Huang W, Chen Z, Shang X, Tian D, Wang D, Wu K, Fan D, Xia L. | 08/8/2015 |
overexpression of FGFBP1 or loss of WISP-2 expression is closely related to the metastasis, invasion and poor prognosis of gallbladder cancer. | A comparative study of clinicopathological significance, FGFBP1, and WISP-2 expression between squamous cell/adenosquamous carcinomas and adenocarcinoma of the gallbladder. Yang Z, Yang Z, Zou Q, Yuan Y, Li J, Li D, Liang L, Zeng G, Chen S. | 12/20/2014 |
FGFBP1 associates with hypertension and that systematic analysis of signaling pathways can identify previously undescribed genetic associations. | Pathway analysis shows association between FGFBP1 and hypertension. Tomaszewski M, Charchar FJ, Nelson CP, Barnes T, Denniff M, Kaiser M, Debiec R, Christofidou P, Rafelt S, van der Harst P, Wang WY, Maric C, Zukowska-Szczechowska E, Samani NJ., Free PMC Article | 07/2/2011 |
Sequence variation in FGFBP1 may contribute to variation in bone mineral density, possibly influencing osteoporosis risk. | A common variant in fibroblast growth factor binding protein 1 (FGFBP1) is associated with bone mineral density and influences gene expression in vitro. Hoppman N, McLenithan JC, McBride DJ, Shen H, Bruder J, Bauer RL, Shaffer JR, Liu J, Streeten EA, Shuldiner AR, Kammerer CM, Mitchell BD, Hoppman N, McLenithan JC, McBride DJ, Shen H, Bruder J, Bauer RL, Shaffer JR, Liu J, Streeten EA, Shuldiner AR, Kammerer CM, Mitchell BD., Free PMC Articles: PMC2902654, PMC2902654 | 10/23/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesAn approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, Miyagawa T, Kawashima M, Tanaka S, Honda Y, Honda M, Tokunaga K. Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC. A common variant in fibroblast growth factor binding protein 1 (FGFBP1) is associated with bone mineral density and influences gene expression in vitro. Hoppman N, McLenithan JC, McBride DJ, Shen H, Bruder J, Bauer RL, Shaffer JR, Liu J, Streeten EA, Shuldiner AR, Kammerer CM, Mitchell BD, Hoppman N, McLenithan JC, McBride DJ, Shen H, Bruder J, Bauer RL, Shaffer JR, Liu J, Streeten EA, Shuldiner AR, Kammerer CM, Mitchell BD. | 06/30/2010 |
KLF5 may promote breast cancer cell proliferation at least partially through directly activating the FGF-BP mRNA transcription. | Krüppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1. Zheng HQ, Zhou Z, Huang J, Chaudhury L, Dong JT, Chen C. | 01/21/2010 |
KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization. | KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization. Liu R, Zheng HQ, Zhou Z, Dong JT, Chen C., Free PMC Article | 01/21/2010 |
Upregulation of FGF-BP expression after injury stimulates FGF activity at the wound site, thus enhancing the process of epithelial repair. | The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair. Beer HD, Bittner M, Niklaus G, Munding C, Max N, Goppelt A, Werner S. | 01/21/2010 |
The upregulation of FGF-BP by regenerating renal tubular epithelial cells may provide a mechanism by which the regenerative and angiogenic activity of FGF-2 in renal capillaries can be modulated in children with HIV-HUS and other renal disease. | Role of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome. Ray PE, Tassi E, Liu XH, Wellstein A. | 01/21/2010 |
the FGF interaction domain is contained in the C terminus of FGF-BP1 | Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display. Xie B, Tassi E, Swift MR, McDonnell K, Bowden ET, Wang S, Ueda Y, Tomita Y, Riegel AT, Wellstein A. | 01/21/2010 |
FGF-BP can be rate-limiting for tumor growth and serves as an angiogenic switch molecule, and that it represents an increasingly promising target molecule in anti-tumor therapy[review] | The fibroblast growth factor-binding protein FGF-BP. Abuharbeid S, Czubayko F, Aigner A. | 01/21/2010 |