| The scaffolding function of LSD1 controls DNA methylation in mouse ESCs. | The scaffolding function of LSD1 controls DNA methylation in mouse ESCs.
Malla S, Kumari K, García-Prieto CA, Caroli J, Nordin A, Phan TTT, Bhattarai DP, Martinez-Gamero C, Dorafshan E, Stransky S, Álvarez-Errico D, Saiki PA, Lai W, Lyu C, Lizana L, Gilthorpe JD, Wang H, Sidoli S, Mateus A, Lee DF, Cantù C, Esteller M, Mattevi A, Roman AC, Aguilo F., Free PMC Article | 10/25/2024 |
| Restoration of TFPI2 by LSD1 inhibition suppresses tumor progression and potentiates antitumor immunity in breast cancer. | Restoration of TFPI2 by LSD1 inhibition suppresses tumor progression and potentiates antitumor immunity in breast cancer.
Gu T, Vasilatos SN, Yin J, Qin Y, Zhang L, Davidson NE, Huang Y., | 09/5/2024 |
| Downregulation of lysine-specific histone demethylase 1A (KDM1A/LSD1) in medial prefrontal cortex facilitates chronic stress-induced pain and emotional dysfunction in female mice. | Downregulation of lysine-specific histone demethylase 1A (KDM1A/LSD1) in medial prefrontal cortex facilitates chronic stress-induced pain and emotional dysfunction in female mice.
Wei SQ, Wei JX, Zhao S, Cao DY, Liang L. | 06/10/2024 |
| LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model. | LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model.
Díez-Sánchez A, Lindholm HT, Vornewald PM, Ostrop J, Yao R, Single AB, Marstad A, Parmar N, Shaw TN, Martín-Alonso M, Oudhoff MJ., Free PMC Article | 05/9/2024 |
| Histone demethylase KDM1A promotes hepatic steatosis and inflammation by increasing chromatin accessibility in NAFLD. | Histone demethylase KDM1A promotes hepatic steatosis and inflammation by increasing chromatin accessibility in NAFLD.
Yang Z, Zhang S, Liu X, Shu R, Shi W, Qu W, Liu D, Cai Z, Wang Y, Cheng X, Liu Y, Zhang XJ, Bai L, Li H, She ZG., Free PMC Article | 04/2/2024 |
| Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses. | Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses.
Mazzarella L, Santoro F, Ravasio R, Fumagalli V, Massa PE, Rodighiero S, Gavilán E, Romanenghi M, Duso BA, Bonetti E, Manganaro L, Pallavi R, Trastulli D, Pallavicini I, Gentile C, Monzani S, Leonardi T, Pasqualato S, Buttinelli G, Di Martino A, Fedele G, Schiavoni I, Stefanelli P, Meroni G, de Francesco R, Steinkuhler C, Fossati G, Iannacone M, Minucci S, Pelicci PG. | 12/29/2023 |
| Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia. | Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
Jiang Q, Stachelscheid J, Bloehdorn J, Pacholewska A, Aszyk C, Grotenhuijs F, Müller T, Onder O, Wagle P, Herling CD, Kleppe M, Wang Z, Coombes KR, Robrecht S, Dalvi PS, Plosnita B, Mayer P, Abruzzo LV, Altmüller J, Gathof B, Persigehl T, Fischer K, Jebaraj B, Rienhoff HY, Ecker R, Zhao Y, Bruns CJ, Stilgenbauer S, Elenitoba-Johnson K, Hallek M, Schweiger MR, Odenthal M, Vasyutina E, Herling M. | 07/23/2023 |
| Lsd1 safeguards T-cell development via suppressing endogenous retroelements and interferon responses. | Lsd1 safeguards T-cell development via suppressing endogenous retroelements and interferon responses.
Xia M, Wang B, Sun W, Ji D, Zhou H, Huang X, Yu M, Su Z, Chen P, Qu K, Wang X., Free PMC Article | 07/17/2023 |
| Lnc_000048 Promotes Histone H3K4 Methylation of MAP2K2 to Reduce Plaque Stability by Recruiting KDM1A in Carotid Atherosclerosis. | Lnc_000048 Promotes Histone H3K4 Methylation of MAP2K2 to Reduce Plaque Stability by Recruiting KDM1A in Carotid Atherosclerosis.
Zhang S, Sun Y, Xiao Q, Niu M, Pan X, Zhu X., Free PMC Article | 03/29/2023 |
| Crucial Role of Lysine-Specific Histone Demethylase 1 in RANKL-Mediated Osteoclast Differentiation. | Crucial Role of Lysine-Specific Histone Demethylase 1 in RANKL-Mediated Osteoclast Differentiation.
Ding M, Chen Z, Cho E, Park SW, Lee TH., Free PMC Article | 03/21/2023 |
| Antagonistic action of GPS2 and KDM1A at enhancers governs alternative macrophage activation by interleukin 4. | Antagonistic action of GPS2 and KDM1A at enhancers governs alternative macrophage activation by interleukin 4.
Huang Z, Efthymiadou A, Liang N, Fan R, Treuter E., Free PMC Article | 02/27/2023 |
| LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle. | LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle.
Araki H, Hino S, Anan K, Kuribayashi K, Etoh K, Seko D, Takase R, Kohrogi K, Hino Y, Ono Y, Araki E, Nakao M., Free PMC Article | 02/4/2023 |
| A NR2E1-interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells. | A NR2E1-interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells.
Hu R, Hameed UFS, Sun X, Moorthy BS, Zhang W, Jeffrey PD, Zhou L, Ma X, Chen F, Pei J, Giri PK, Mou Y, Swaminathan K, Yuan P., Free PMC Article | 01/14/2023 |
| Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity. | Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.
Ramms B, Pollow DP, Zhu H, Nora C, Harrington AR, Omar I, Gordts PLSM, Wortham M, Sander M., Free PMC Article | 12/3/2022 |
| CircRNA AFF4 induced by KDM1A promotes osteogenic differentiation through FNDC5/Irisin pathway. | CircRNA AFF4 induced by KDM1A promotes osteogenic differentiation through FNDC5/Irisin pathway.
Liu A, Chen Y, Zhong D, Wang C, Yu M, Liu C, Yang Z, Chen W, Yin K., Free PMC Article | 12/3/2022 |
| Mechanism of LSD1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the miR-21-5p/NLRP12 axis. | Mechanism of LSD1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the miR-21-5p/NLRP12 axis.
Yu X, Niu T, Liu C., Free PMC Article | 11/19/2022 |
| Lysine-specific demethylase 1 aggravated oxidative stress and ferroptosis induced by renal ischemia and reperfusion injury through activation of TLR4/NOX4 pathway in mice. | Lysine-specific demethylase 1 aggravated oxidative stress and ferroptosis induced by renal ischemia and reperfusion injury through activation of TLR4/NOX4 pathway in mice.
Feng R, Xiong Y, Lei Y, Huang Q, Liu H, Zhao X, Chen Z, Chen H, Liu X, Wang L, Weng X., Free PMC Article | 08/6/2022 |
| LSD1 regulates the expressions of core cardiogenic transcription factors and cardiac genes in oxygen and glucose deprivation injured mice fibroblasts in vitro. | LSD1 regulates the expressions of core cardiogenic transcription factors and cardiac genes in oxygen and glucose deprivation injured mice fibroblasts in vitro.
Cao Y, Dong Z, Yang D, Ma X, Wang X. | 07/30/2022 |
| LSD1 downregulates p21 expression in vascular smooth muscle cells and promotes neointima formation. | LSD1 downregulates p21 expression in vascular smooth muscle cells and promotes neointima formation.
Yuan B, Liu H, Pan X, Dong X, Qu LF, Sun J, Pan LL. | 07/23/2022 |
| Histone demethylase LSD1 is critical for endochondral ossification during bone fracture healing. | Histone demethylase LSD1 is critical for endochondral ossification during bone fracture healing.
Sun J, Feng H, Xing W, Han Y, Suo J, Yallowitz AR, Qian N, Shi Y, Greenblatt MB, Zou W., Free PMC Article | 04/30/2022 |
| LSD1 deletion decreases exosomal PD-L1 and restores T-cell response in gastric cancer. | LSD1 deletion decreases exosomal PD-L1 and restores T-cell response in gastric cancer.
Shen DD, Pang JR, Bi YP, Zhao LF, Li YR, Zhao LJ, Gao Y, Wang B, Wang N, Wei L, Guo H, Liu HM, Zheng YC., Free PMC Article | 04/30/2022 |
| Lysine-specific demethylase 1 as a corepressor of mineralocorticoid receptor. | Lysine-specific demethylase 1 as a corepressor of mineralocorticoid receptor.
Kohata N, Kurihara I, Yokota K, Kobayashi S, Murai-Takeda A, Mitsuishi Y, Nakamura T, Morisaki M, Kozuma T, Torimitsu T, Kawai M, Itoh H. | 04/23/2022 |
| Salt Sensitivity of Blood Pressure and Aldosterone: Interaction Between the Lysine-specific Demethylase 1 Gene, Sex, and Age. | Salt Sensitivity of Blood Pressure and Aldosterone: Interaction Between the Lysine-specific Demethylase 1 Gene, Sex, and Age.
Parksook WW, Heydarpour M, Gholami SK, Luther JM, Hopkins PN, Pojoga LH, Williams JS., Free PMC Article | 04/23/2022 |
| LSD1-mediated stabilization of SEPT6 protein activates the TGF-beta1 pathway and regulates non-small-cell lung cancer metastasis. | LSD1-mediated stabilization of SEPT6 protein activates the TGF-β1 pathway and regulates non-small-cell lung cancer metastasis.
Hong Y, Li X, Zhu J. | 04/9/2022 |
| Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1. | Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1.
Cao Y, Tang L, Du K, Paraiso K, Sun Q, Liu Z, Ye X, Fang Y, Yuan F, Chen H, Chen Y, Wang X, Yu C, Blitz IL, Wang PH, Huang L, Cheng H, Lu X, Cho KW, Seldin M, Fang Z, Yang Q., Free PMC Article | 03/26/2022 |