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Series GSE102006 Query DataSets for GSE102006
Status Public on Jul 29, 2017
Title Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To unravel the underlying mechanisms of inflammation-related idiosyncratic drug toxicity
 
Overall design HepG2 cells were exposed to 3 idiosyncratic and 3 non-idiosyncratic compounds with or without the cytokine mix (TNF 100 ng/ml + IFNγ 100 ng/ml + IL-1α 20 ng/ml + IL-6 20 ng/ml + LPS 10 µg/ml)as described previously (Cosgrove et al., 2009) for 6, 12 or 24 h.
 
Contributor(s) Jiang J, Mathijs K, Timmermans L, Claessen SM, Hecka A, Weusten J, Peters R, van Delft JH, Kleinjans JC, Jennen DG, de Kok TM
Citation(s) 28733206, 28831409
Submission date Jul 28, 2017
Last update date Jul 25, 2021
Contact name Jian Jiang
E-mail(s) [email protected]
Phone 0684063016
Organization name Maastricht University
Department Toxicogenomics
Street address Maastricht University
City Maastricht
ZIP/Postal code 6200 MD
Country Netherlands
 
Platforms (1)
GPL6480 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Samples (252)
GSM2720393 HepG2_DMSO_with_cytokines_6h_exp1
GSM2720394 HepG2_DMSO_without_cytokines_6h_exp1
GSM2720395 HepG2_DMSO_with_cytokines_12h_exp1
Relations
BioProject PRJNA396205

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE102006_RAW.tar 2.2 Gb (http)(custom) TAR (of TXT)
Processed data included within Sample table
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