|
| Status |
Public on Mar 01, 2019 |
| Title |
Genome-wide microRNA screening in Nile tilapia reveals pervasive transcription of isomiRs, sex-biased arm switching and increasing complexity of expression throughout development |
| Organism |
Oreochromis niloticus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
The elucidation of microRNA function and evolution depends on the identification and characterization of miRNA repertoire of strategic organisms, as the fast evolving cichlid fishes. Using RNA-seq and comparative genomics we carried out an in-depth report of miRNAs in Nile tilapia (Oreochromis niloticus). Our results enlarge vertebrate
miRNAs collection and reveal a notable differential expression of miRNAs arms and isoforms influenced by sex and developmental life stage, providing a better picture of the evolutionary and spatiotemporal dynamics of miRNAs.
|
| |
|
| Overall design |
Discovery and evolutionary analysis of microRNAs
|
| |
|
| Contributor(s) |
Pinhal D, Bovolenta LA |
| Citation(s) |
32707870 |
| |
| Submission date |
Aug 21, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Danillo Pinhal |
| E-mail(s) |
[email protected]
|
| Organization name |
Sao Paulo State University
|
| Department |
Genetics
|
| Lab |
Laboratory Genomics and Molecular Evolution
|
| Street address |
R. Prof. Dr. Antonio C. W. Zanin s/n
|
| City |
Botucatu |
| State/province |
SP |
| ZIP/Postal code |
18618689 |
| Country |
Brazil |
| |
|
| Platforms (1) |
| GPL23168 |
Illumina Genome Analyzer IIx (Oreochromis niloticus) |
|
| Samples (16)
|
|
| Relations |
| BioProject |
PRJNA399148 |
| SRA |
SRP115909 |
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