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| Status |
Public on Sep 22, 2017 |
| Title |
Effect of blood product - derived Cell Free Nucleic Acids (CFNA) on peripheral mononuclear cells gene regulation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
PBMC were exposed to Cell Free Nucleic Acids (CFNA) extracted from blood products eligible for transfusion: Red Blood Cell units (RBC), Fresh Frozen Plasma units (FFP). PBMC alone exposed to the same extract from PBS were used as a control (PBMC+control). PBMC alone were also used as control. The used positive control was PBMC exposed to Lipopolysaccharide (LPS)
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| |
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| Overall design |
exposition of PBMC to CFNA, RNA extarction and gene expression array (24h)
PFC = FFP = Fresh Frozen Plasma units
CE = RBC = Red Blood Cell units
CP = PC = Platelet Concentrates
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| |
|
| Contributor(s) |
Lau P, Tirefort D, Preynat-Seauve O |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 21, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Celine Delucinge |
| Organization name |
University of Geneva
|
| Department |
iGE3 Genomics Platform
|
| Street address |
1 rue Michel Servet
|
| City |
Geneva |
| ZIP/Postal code |
1211 |
| Country |
Switzerland |
| |
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| Platforms (1) |
| GPL16043 |
GeneChip® PrimeView™ Human Gene Expression Array (with External spike-in RNAs) |
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| Samples (23)
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| This SubSeries is part of SuperSeries: |
| GSE104109 |
Effect of cell free nucleic acids extracted from blood products on human leukocytes gene regulation: mononuclear cells and macrophages |
|
| Relations |
| BioProject |
PRJNA408252 |
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