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Series GSE116975 Query DataSets for GSE116975
Status Public on Nov 15, 2020
Title Results from analysis of microarray data from clinical trial NCT00805389
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The analysis was performed in 2 parts: a descriptive analysis of the response within each adjuvant group and an analysis at the individual subject level. We used blood transcriptional modules to perform interpretation of the results.
 
Overall design There are 924 samples from 112 subjects, divided into 5 adjuvant groups: respectively 18, 23, 28, 22 and 21 in the AS01B, AS01E, AS03A, AS04 and Alum groups, respectively. Subjects were injected with 2 doses of Hepatitis B + adjuvant at Day 0 (D0) and Day 30 (D30). Whole blood samples were collected at the following time points: D0 pre-vaccination (D0_pre), D0 3 to 6 hours post-vaccination (D0_post), D1, D14, D30 pre-vaccination (D30_pre), D30 3 to 6 hours post-vaccination (D0_post), D31, D33 and D37.
 
Contributor(s) De Mot L, Bechtold V, Burny W, Hasdemir D, Callegaro A, Siena E, Coccia M, Bol V, Legrand C, Ndour C, Essaghir A, Montoya FU, van den Berg R, Smilde A, Didierlaurent A, van der Most R
Citation(s) 33177181
Submission date Jul 12, 2018
Last update date Feb 15, 2021
Contact name Robbert Gerrit van der Most
E-mail(s) [email protected]
Organization name GSK
Street address 89, rue de l'Institut
City Rixensart
ZIP/Postal code 1330
Country Belgium
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (924)
GSM4554057 Whole blood, Day 30 post, PID 102
GSM4554058 Whole blood, Day 37, PID 48
GSM4554059 Whole blood, Day 0 post, PID 36
Relations
BioProject PRJNA480771

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE116975_RAW.tar 3.9 Gb (http)(custom) TAR (of CEL)
GSE116975_Sample_complete_characteristics_metadata.xlsx 926.0 Kb (ftp)(http) XLSX
Processed data included within Sample table

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