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Series GSE136808 Query DataSets for GSE136808
Status Public on Apr 07, 2020
Title Inactivation of the nuclear interacting SET domain protein 1 (NSD1) impairs GATA1-regulated erythroid differentiation and causes erythroleukemia. NSD1 Add-back experiment. ChIPSeq for Gata1, H3K27ac and H3K36me3.
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary In vitro differentiation of Nsd1-/- erythroblasts with retroviral expression of wildtype Nsd1, or a catalytically-inactive Nsd1N1918Q SET-domain
 
Overall design Add-back experiment with cultured Nsd1-/- erythroblasts rescued with either retroviral expression of wildtype Nsd1, or a catalytically-inactive Nsd1N1918Q SET-domain
 
Contributor(s) Leonards K, Almosailleakh M, Tauchmann S, Bagger FO, Ivanek R, Schwaller J
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Sep 03, 2019
Last update date Nov 17, 2021
Contact name DBM Bioinformatics Core Facility
Phone +41612073541
Organization name University of Basel
Department Departement of Biomedicine
Street address Hebelstrasse 20
City Basel
State/province BS
ZIP/Postal code 4053
Country Switzerland
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (40)
GSM4058402 Nsd1KO_none_Maintainance_Gata1_rep1
GSM4058403 Nsd1KO_none_Maintainance_H3K27ac_rep1
GSM4058404 Nsd1KO_none_Maintainance_Input_rep1
This SubSeries is part of SuperSeries:
GSE136811 Inactivation of the nuclear interacting SET domain protein 1 (NSD1) impairs GATA1-regulated erythroid differentiation and causes erythroleukemia.
Relations
BioProject PRJNA563707
SRA SRP220192

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE136808_RAW.tar 18.2 Gb (http)(custom) TAR (of BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
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