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| Status |
Public on Oct 07, 2019 |
| Title |
Nivolumab treatment for relapsed/refractory Epstein-Barr virus-associated hemophagocytic lymphohistocytosis in adults |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Single cell RNA sequencing (scRNA-seq) was performed with peripheral blood cells before (Day 0, T0), during nivolumab treatment (Day 7, T1; Day 21, T2), and when plasma EBV turned negative (Day 76, T3) in 1 patient (patient 7). scRNA-seq libraries were generated following the recommended protocol of the 3’ scRNA-seq 10X genomics platform and using v2 chemistry, and sequenced data was collected by illumina NovaSeq 6000 sequencing.
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| Overall design |
Single cell RNA sequencing (scRNA-seq) in 4 stages
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| Contributor(s) |
Liu P, Pan X, Chen C, Niu T, Shuai X, Wang J, Chen X |
| Citation(s) |
31914172 |
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| Submission date |
Oct 07, 2019 |
| Last update date |
Apr 02, 2020 |
| Contact name |
Xaingyu Pan |
| E-mail(s) |
[email protected]
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| Organization name |
Sichuan University
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| Department |
State Key Laboratory of Biotherapy, West China Hospital, Sihcuan University.
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| Lab |
Chen & Liu Lab
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| Street address |
No.17 Renming road section3
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| City |
Chengdu, Cihna |
| State/province |
Sichuan |
| ZIP/Postal code |
610041 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA576213 |
| SRA |
SRP224614 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE138504_RAW.tar |
1.0 Gb |
(http)(custom) |
TAR (of RDS, TXT) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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