|
| Status |
Public on Apr 16, 2020 |
| Title |
Analysis of transcriptomic responses of genotoxic stress in human HepaRG hepatocarcinoma cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: Toxicogenomics analyses may provide information about DNA-damaging properties of test compounds but are not routinely used for identification of a genotoxic potential. In this study, metabolically active human HepaRG hepatocarcinoma cells were exposed to six food-relevant genotoxic carcinogens.
Method: Transcriptomic responses were analyzed using RNA sequencing technology
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| |
|
| Overall design |
Examination with a total of 21 samples, thereof 6 control samples and 15 samples in 5 treatment groups in triplicates
|
| |
|
| Contributor(s) |
Kreuzer K, Böhmert L, Braeuning A |
| Citation(s) |
32234424 |
| |
| Submission date |
Mar 06, 2020 |
| Last update date |
Sep 21, 2021 |
| Contact name |
Katrin Kreuzer |
| E-mail(s) |
[email protected]
|
| Organization name |
German Federal Institute for Risk Assessment
|
| Department |
Food Safety
|
| Street address |
Max-Dohrn-Str. 8-10
|
| City |
Berlin |
| ZIP/Postal code |
10589 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (21)
|
|
| Relations |
| BioProject |
PRJNA610841 |
| SRA |
SRP251883 |
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