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| Status |
Public on Jun 25, 2021 |
| Title |
RNA-seq analysis of peripheral nerve with conditional knockout of H3K27 demethylases. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goal of the experiment was to determine the role of H3 emethylases in the nerve injury response in peripheral nerve. A Schwann cell specific knockout of the H3K27 demethylases (Jmjd3 and Utx) was generated to compare with wild type mice in sham and injured mice at 1d and 7d timepoints after nerve injury.
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| Overall design |
For each condition, three independent biological replicates were prepared.
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| Contributor(s) |
Duong P, Svaren J |
| Citation(s) |
34090875 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 NS100510 |
Epigenetic Regulation of Nerve Injury |
UNIVERSITY OF WISCONSIN MADISON |
John P Svaren |
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| |
| Submission date |
Jun 24, 2021 |
| Last update date |
Jun 25, 2021 |
| Contact name |
John Svaren |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Wisconsin
|
| Department |
Comparative Biosciences
|
| Lab |
Waisman Center
|
| Street address |
1500 Highland Ave.
|
| City |
Madison |
| State/province |
WI |
| ZIP/Postal code |
53705 |
| Country |
USA |
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| Platforms (2) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (41)
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| Relations |
| BioProject |
PRJNA741269 |
| SRA |
SRP325543 |
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