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| Status |
Public on Aug 08, 2021 |
| Title |
Loss of PRC1 in Uveal melanoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
We demonstrated that loss of Histone 2A Ubiquitination and PRC1 activity drives uveal melanoma progression
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| Overall design |
RNA-seq and CUT&RUN of Uveal melanoma cell lines
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| Contributor(s) |
Bakhoum MF, Francis JH, Agustinus A, Earlie EM, Di Bona M, Abramson DH, Duran M, Masilionis I, Molina E, Shoushtari AN, Goldbaum MH, Mischel PS, Bakhoum SF, Laughney AM |
| Citation(s) |
34518527 |
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| Submission date |
Aug 06, 2021 |
| Last update date |
Oct 13, 2021 |
| Contact name |
Mathieu F Bakhoum |
| Organization name |
Yale University
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| Department |
Ophthalmology
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| Lab |
Bakhoum Laboratory
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| Street address |
300 George St.
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| City |
New Haven |
| State/province |
CT |
| ZIP/Postal code |
06510 |
| Country |
USA |
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| Platforms (2) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (62)
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| Relations |
| BioProject |
PRJNA752631 |
| SRA |
SRP331395 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE181600_CUT_RUNPeaks.txt.gz |
10.9 Mb |
(ftp)(http) |
TXT |
| GSE181600_Exp1_Gene_normalized_counts.txt.gz |
2.0 Mb |
(ftp)(http) |
TXT |
| GSE181600_Exp2_Gene_normalized_counts.txt.gz |
1.9 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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