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| Status |
Public on Jun 28, 2022 |
| Title |
The Transcription Factor ThPOK Regulates ILC3 Lineage Homeostasis and Function during Intestinal Infection II |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the role of ThPOK in the regulation of ILC3 development and function, we established conventional ThPOK knockout mice and carried out single-cell RNA sequencing (BD Rhapsody) on intestinal ILC3s.
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| Overall design |
ILC3s from 6-week-old male C57BL/6 mice were isolated from the small intestine and analyzed by single-cell RNA sequencing technology (BD Rhapsody).
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| Contributor(s) |
Gao X, Wang L |
| Citation(s) |
35844574 |
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| Submission date |
May 24, 2022 |
| Last update date |
Sep 27, 2022 |
| Contact name |
lie wang |
| E-mail(s) |
[email protected]
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| Organization name |
zhejiang universiry
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| Department |
immunology
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| Street address |
Zijingang Campus, Zhejiang Universityļ¼Yuhangtang Road 866
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| City |
hangzhou |
| State/province |
zhejiang |
| ZIP/Postal code |
310058 |
| Country |
China |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (3) |
| GSM6185996 |
Group 3 innate lymphoid cell, WT rep1, scRNAseq |
| GSM6185997 |
Group 3 innate lymphoid cell, WT rep2, scRNAseq |
| GSM6185998 |
Group 3 innate lymphoid cell, ThPOK-deficient rep1 and 2, scRNAseq |
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| Relations |
| BioProject |
PRJNA841977 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE204698_RAW.tar |
88.1 Mb |
(http)(custom) |
TAR (of CSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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