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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Oct 12, 2023 |
| Title |
Effect of PDGF, TGF-β and miR-221 on gene expression during proliferation and differentiation of human aortic smooth muscle cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the key molecular and mechanism during the proliferation and differentiation of human aortic smooth muscle cells, we treated HASMC cell lines with PDGF, TGF-β and miR-221.We then performed gene expression profiling analysis using data obtained from ONT long-read RNA-seq of 4 different treatment.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for control HASMC cells and 3 different treatments (PDGF, TGF-β and miR-221).
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| Contributor(s) |
Li S, Kong D, Lv Z, Lv Y, Wu H |
| Citation(s) |
37907652 |
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| Submission date |
Jul 25, 2022 |
| Last update date |
Nov 16, 2023 |
| Contact name |
wu hao |
| E-mail(s) |
[email protected]
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| Phone |
19821361851
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| Organization name |
Shanghai General Hospital
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| Department |
Precision Research Center for Refractory Diseases, Institute for Clinical Research
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| Street address |
No. 650 Xin Songjiang Road
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| City |
shanghai |
| State/province |
shanghai |
| ZIP/Postal code |
201613 |
| Country |
China |
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| Platforms (2) |
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| Samples (32)
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| GSM6387643 |
HASMC,miR-221 mimic, sample 4 |
| GSM6387644 |
HASMC,NC mimic, sample 1 |
| GSM6387645 |
HASMC,NC mimic, sample 2 |
| GSM6387646 |
HASMC,NC mimic, sample 3 |
| GSM6387647 |
HASMC,NC mimic, sample 4 |
| GSM6387648 |
HASMC,PDGF,sample 1 |
| GSM6387649 |
HASMC,PDGF,sample 2 |
| GSM6387650 |
HASMC,PDGF,sample 3 |
| GSM6387651 |
HASMC,PDGF,sample 4 |
| GSM6387652 |
HASMC,TGF-β,sample 1 |
| GSM6387653 |
HASMC,TGF-β,sample 2 |
| GSM6387654 |
HASMC,TGF-β,sample 3 |
| GSM6387655 |
HASMC,TGF-β,sample 4 |
| GSM7182507 |
HASMC,miR-221 mimic,illumina, sample 1 |
| GSM7182508 |
HASMC,miR-221 mimic,illumina, sample 2 |
| GSM7182509 |
HASMC,miR-221 mimic,illumina, sample 3 |
| GSM7182510 |
HASMC,miR-221 mimic,illumina, sample 4 |
| GSM7182511 |
HASMC,NC mimic,illumina, sample 1 |
| GSM7182512 |
HASMC,NC mimic,illumina, sample 2 |
| GSM7182513 |
HASMC,NC mimic,illumina,sample 3 |
| GSM7182514 |
HASMC,NC mimic,illumina, sample 4 |
| GSM7182515 |
HASMC,PDGF,illumina, sample 1 |
| GSM7182516 |
HASMC,PDGF,illumina, sample 2 |
| GSM7182517 |
HASMC,PDGF,illumina, sample 3 |
| GSM7182518 |
HASMC,PDGF,illumina, sample 4 |
| GSM7182519 |
HASMC,TGF-β,illumina, sample 1 |
| GSM7182520 |
HASMC,TGF-β,illumina, sample 2 |
| GSM7182521 |
HASMC,TGF-β,illumina, sample 3 |
| GSM7182522 |
HASMC,TGF-β,illumina, sample 4 |
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| Relations |
| BioProject |
PRJNA862176 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE209739_Illumina_gene_count_matrix.csv.gz |
1.2 Mb |
(ftp)(http) |
CSV |
| GSE209739_Illumina_transcript_count_matrix.csv.gz |
3.1 Mb |
(ftp)(http) |
CSV |
| GSE209739_ONT_transcript_TPM_matrix.csv.gz |
22.6 Mb |
(ftp)(http) |
CSV |
| GSE209739_ONT_transcript_count_matrix.csv.gz |
16.0 Mb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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