|
| Status |
Public on Aug 01, 2023 |
| Title |
Fission yeast poly(A) polymerase active site mutation Y86D suppresses the rad24∆ aps1-H397A synthetic growth defect and upregulates mRNAs targeted by Mmi1/MTREC |
| Organism |
Schizosaccharomyces pombe |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This RNA-Seq analysis compares gene expression of the pla1-Y86D mutant contrasting to the isogenic wild-type fission yeast (Schizosaccharomyces pombe).
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| |
|
| Overall design |
1 test samples and 1 control sample was processed (each sample has 3 replicate experiments)
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| |
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| Contributor(s) |
Garg A, Shuman S, Schwer B |
| Citation(s) |
37586723 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R35 GM126945 |
Mechanisms of DNA and RNA Transactions |
Sloan Kettering Institute for Cancer Research |
Stewart H Shuman |
| R01 GM134021 |
Inositol pyrophosphate dynamics affect RNA 3'-processing/transcription termination |
WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY |
Beate Schwer |
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| |
| Submission date |
Dec 20, 2022 |
| Last update date |
Nov 13, 2023 |
| Contact name |
Angad Garg |
| Organization name |
Memorial Sloan Kettering Cancer Center
|
| Department |
Molecular Biology
|
| Lab |
Stewart Shuman
|
| Street address |
RRL-865 430 E 67th St.
|
| City |
New York |
| State/province |
New York |
| ZIP/Postal code |
10065 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL28961 |
Illumina NovaSeq 6000 (Schizosaccharomyces pombe) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA914304 |
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