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| Status |
Public on Sep 06, 2023 |
| Title |
Transcriptomic analysis reveals the dynamic changes of immune responses during the development of creeping fat in Crohn's disease |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In Crohn's disease, creeping fat is the characteristic expansion of mesenteric adipose tissue wrapping around the inflamed intestine. Through a comparative transcriptomic analysis of creeping fat and normal-looking mesenteric adipose tissues from patients with Crohn's disease and non-Crohn's disease, we found that a dynamic transcriptional and cell compositional change occurs during the progression from non-Crohn's disease to Crohn's disease, and finally to creeping fat.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for patients with CD CF, CD MAT and Con MAT.
**Submitter declares that the raw data cannot be deposited due to hospital policy**
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| Contributor(s) |
Kim K, Park S, Lee Y |
| Citation(s) |
37594364 |
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| Submission date |
Mar 14, 2023 |
| Last update date |
Sep 06, 2023 |
| Contact name |
SoJung Park |
| E-mail(s) |
[email protected]
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| Organization name |
Ulsan medical university
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| Street address |
88, Olympic-ro 43-gil
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| City |
Seoul |
| State/province |
Songpa-gu |
| ZIP/Postal code |
05505 |
| Country |
South Korea |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (59)
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| GSM7099414 |
FP42, CD participants, pair sample, Creeping fat |
| GSM7099415 |
FP45, CD participants, pair sample, Creeping fat |
| GSM7099416 |
FP48, CD participants, pair sample, Creeping fat |
| GSM7099417 |
FP50, CD participants, pair sample, Creeping fat |
| GSM7099418 |
FP51, CD participants, pair sample, Creeping fat |
| GSM7099419 |
FP52, CD participants, pair sample, Creeping fat |
| GSM7099420 |
FP54, CD participants, pair sample, Creeping fat |
| GSM7099421 |
FP56, CD participants, pair sample, Creeping fat |
| GSM7099422 |
FP57, CD participants, pair sample, Creeping fat |
| GSM7099423 |
FP58, CD participants, pair sample, Creeping fat |
| GSM7099424 |
FP60, CD participants, pair sample, Creeping fat |
| GSM7099425 |
FP61, CD participants, pair sample, Creeping fat |
| GSM7099426 |
FP62, CD participants, pair sample, Creeping fat |
| GSM7099427 |
FP63, CD participants, pair sample, Creeping fat |
| GSM7099428 |
FP65, CD participants, pair sample, Creeping fat |
| GSM7099429 |
FP67, CD participants, pair sample, Creeping fat |
| GSM7099430 |
FP68, CD participants, pair sample, Creeping fat |
| GSM7099431 |
FP69, CD participants, pair sample, Creeping fat |
| GSM7099432 |
FP71, CD participants, pair sample, Creeping fat |
| GSM7099433 |
FP72, CD participants, pair sample, Creeping fat |
| GSM7099434 |
FP74, CD participants, pair sample, Creeping fat |
| GSM7099435 |
FP77, CD participants, pair sample, Creeping fat |
| GSM7099436 |
FP82, CD participants, pair sample, Creeping fat |
| GSM7099437 |
FN42, CD participants, pair sample, CD mesenteric fat |
| GSM7099438 |
FN45, CD participants, pair sample, CD mesenteric fat |
| GSM7099439 |
FN48, CD participants, pair sample, CD mesenteric fat |
| GSM7099440 |
FN50, CD participants, pair sample, CD mesenteric fat |
| GSM7099441 |
FN51, CD participants, pair sample, CD mesenteric fat |
| GSM7099442 |
FN52, CD participants, pair sample, CD mesenteric fat |
| GSM7099443 |
FN54, CD participants, pair sample, CD mesenteric fat |
| GSM7099444 |
FN56, CD participants, pair sample, CD mesenteric fat |
| GSM7099445 |
FN57, CD participants, pair sample, CD mesenteric fat |
| GSM7099446 |
FN58, CD participants, pair sample, CD mesenteric fat |
| GSM7099447 |
FN60, CD participants, pair sample, CD mesenteric fat |
| GSM7099448 |
FN61, CD participants, pair sample, CD mesenteric fat |
| GSM7099449 |
FN62, CD participants, pair sample, CD mesenteric fat |
| GSM7099450 |
FN63, CD participants, pair sample, CD mesenteric fat |
| GSM7099451 |
FN65, CD participants, pair sample, CD mesenteric fat |
| GSM7099452 |
FN67, CD participants, pair sample, CD mesenteric fat |
| GSM7099453 |
FN68, CD participants, pair sample, CD mesenteric fat |
| GSM7099454 |
FN69, CD participants, pair sample, CD mesenteric fat |
| GSM7099455 |
FN71, CD participants, pair sample, CD mesenteric fat |
| GSM7099456 |
FN72, CD participants, pair sample, CD mesenteric fat |
| GSM7099457 |
FN74, CD participants, pair sample, CD mesenteric fat |
| GSM7099458 |
FN77, CD participants, pair sample, CD mesenteric fat |
| GSM7099459 |
FN82, CD participants, pair sample, CD mesenteric fat |
| GSM7099460 |
UC100, Control participants, control sample, UC mesenteric fat |
| GSM7099461 |
UC92, Control participants, control sample, UC mesenteric fat |
| GSM7099462 |
UC94, Control participants, control sample, UC mesenteric fat |
| GSM7099463 |
CFN02, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099464 |
CFN03, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099465 |
CFN04, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099466 |
CFN05, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099467 |
CFN09, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099468 |
CFN11, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099469 |
CFN01, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099470 |
CFN06, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099471 |
CFN07, Control participants, control sample, non-IBD mesenteric fat |
| GSM7099472 |
CFN12, Control participants, control sample, non-IBD mesenteric fat |
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| Relations |
| BioProject |
PRJNA944790 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE227376_TPM_matrix.txt.gz |
6.2 Mb |
(ftp)(http) |
TXT |
| Processed data are available on Series record |
| Raw data not provided for this record |
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