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| Status |
Public on Nov 19, 2012 |
| Title |
JmjD2d-dependence of LPS-induced genes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
In dendritic cells, expression of the H3K9me3 demethylase JmjD2d is upregulated by LPS stimulation. To identify genes whose induction by LPS depends on JmjD2d activity, we performed a microarray analysis of wild-type and JmjD2d-knockdown dendritic cells, before and after stimulation with LPS.
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| Overall design |
RNA was extracted from three independent cultures of wild-type and JmjD2d-knockdown dendritic cells, before and 4h after stimulation with 100ng/ml LPS. The unstimulated and stimulated wild-type samples, and the stimulated JmjD2d-knockdown samples, were used for microarray analysis.
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| Contributor(s) |
Zhu Y, van Essen D, Saccani S |
| Citation(s) |
22633489 |
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| Submission date |
Sep 20, 2011 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Dominic van Essen |
| Organization name |
Institute for Research on Cancer & Aging, Nice (IRCAN)
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| Lab |
Transcription specificity
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| Street address |
28 Avenue Valombrose
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| City |
Nice |
| ZIP/Postal code |
06107 |
| Country |
France |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (9)
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| GSM799198 |
WT DCs, unstimulated, biological rep 1 |
| GSM799199 |
WT DCs, 4h LPS-stimulated, biological rep 1 |
| GSM799200 |
JmjD2d knock-down DCs, 4h LPS-stimulated, biological rep 1 |
| GSM799201 |
WT DCs, unstimulated, biological rep 2 |
| GSM799202 |
WT DCs, 4h LPS-stimulated, biological rep 2 |
| GSM799203 |
JmjD2d knock-down DCs, 4h LPS-stimulated, biological rep 2 |
| GSM799204 |
WT DCs, unstimulated, biological rep 3 |
| GSM799205 |
WT DCs, 4h LPS-stimulated, biological rep 3 |
| GSM799206 |
JmjD2d knock-down DCs, 4h LPS-stimulated, biological rep 3 |
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| This SubSeries is part of SuperSeries: |
| GSE32381 |
Cell-type specific control of enhancer activity by H3K9 trimethylation |
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| Relations |
| BioProject |
PRJNA154881 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE32255_RAW.tar |
39.9 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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