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Series GSE3406 Query DataSets for GSE3406
Status Public on Mar 31, 2006
Title Expression patterns in stress conditions of 4 closely related yeast species from the Saccharomyces sensu stricto complex
Platform organism Saccharomyces cerevisiae
Sample organisms Saccharomyces cerevisiae; Saccharomyces paradoxus; Saccharomyces kudriavzevii; Saccharomyces mikatae
Experiment type Expression profiling by array
Summary We characterize the genome-wide transcription response of four related yeast species and two strains to equivalent environmental stresses.
Keywords: Comparative analysis of gene expression across species.
 
Overall design We chose four yeast species, three species are represented by a single strain (S. cerevisiae, S. kudriavzevii and S. mikatae) and one species (S. paradoxus) is represented by two strains. The five different cell types were subjected to five environmental stresses: heat shock, oxidative stress (H2O2), growth on glycerol, nitrogen starvation and DNA damage (MMS). In each experiment, cells were grown to mid log-phase in rich media and were then subjected to the particular stress. The same growth media was used for all species. The genome-wide transcription profile of each culture was measured at six subsequent time points, from 10 to 90 minutes after the onset of the perturbation (one day for nitrogen starvation). At each time point, gene expression levels were measured relative to a reference (same culture before transfer to stressful media).
 
Contributor(s) Weinberger A, Tirosh I, Barkai N
Citation(s) 16783381
Submission date Oct 03, 2005
Last update date Mar 16, 2012
Contact name Naama Barkai
E-mail(s) [email protected]
Organization name The Weizmann Institute of Science
Department Molecular Genetics
Lab Naama Barkai
Street address Hertzel
City Rehovot
ZIP/Postal code 76100
Country Israel
 
Platforms (1)
GPL2910 UHN Yeast 6.4kv6
Samples (191)
GSM76723 S. cerevisiae Heat shock (37oC) 10 minutes
GSM76724 S. cerevisiae Heat shock (37oC) 20 minutes
GSM76725 S. cerevisiae Heat shock (37oC) 30 minutes
Relations
BioProject PRJNA93423

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