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Status |
Public on Oct 26, 2012 |
Title |
Macrophage samples from the HMDP |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Identify genes involved in regulation of inflammatory responses and gene-environemnt interactions, in macrophages from a set of mouse inbred strains termed the HMDP. The HMDP is a genetically diverse mapping panel comprised of classical inbred and recombinant inbred wild type mice. The RMA values of genes were used for genome wide association as described in Bennett et al Genome Research 2010.
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Overall design |
GWAS for expression in primary macrophages of mouse inbred strains. Macrophages were exposed to bacterial lipopolysaccharide (LPS), oxidized lipids (OxPAPC) or control treatment conditions.
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Contributor(s) |
Orozco LD, Bennett BJ, Lusis AJ |
Citation(s) |
23101632, 27558669, 28737175, 31568751 |
NIH grant(s) |
Grant ID |
Grant title |
Affiliation |
Name |
P01 HL030568 |
Systems Genetics Approach to Atherosclerosis |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
Aldons Jake Lusis |
P01 HL028481 |
Molecular Genetic Approaches in Atherosclerosis Research |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
Aldons Jake Lusis |
DP3 DK094311 |
Systems Genetics of Type 1 Diabetes Complications |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
Aldons Jake Lusis |
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Submission date |
Jun 13, 2012 |
Last update date |
Apr 06, 2021 |
Contact name |
Calvin Pan |
Organization name |
UCLA
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Street address |
675 Charles Young Dr South
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City |
Los Angeles |
ZIP/Postal code |
90095 |
Country |
USA |
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Platforms (1) |
GPL8759 |
[HT_MG-430A] Affymetrix HT Mouse Genome 430A Array |
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Samples (511)
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Relations |
BioProject |
PRJNA168452 |