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Series GSE40867 Query DataSets for GSE40867
Status Public on Dec 05, 2013
Title Global mapping of estrogen receptor and histone modifications in breast tumor samples uncovers distinct patterns for aromatase inhibitor resistance
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary ChIP-seq on primary breast cancer tumor samples for Era, H3K4me3, H3K27me3. Patients had a poor or good outcome after aromatase inhibitor treatment. Differential binding patterns between good and poor outcome patients were identified for each marker, predicting response to treatment
 
Overall design comparing ER, H3K4me3 and H3K27me3 patterns between two breast cancer patient populations
 
Contributor(s) Zwart W, Velds A
Citation(s) 24242068, 26484094
Submission date Sep 13, 2012
Last update date Jul 31, 2019
Contact name Wilbert Zwart
Organization name NKI
Street address Plesmanlaan 121
City Amsterdam
ZIP/Postal code 1066CX
Country Netherlands
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (36)
GSM1003708 good outcome_1_ER
GSM1003709 good outcome_1_H3K4me3
GSM1003710 good outcome_1_H3K27me3
Relations
BioProject PRJNA175144
SRA SRP015749

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40867_RAW.tar 7.5 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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