|
Status |
Public on Dec 05, 2013 |
Title |
Global mapping of estrogen receptor and histone modifications in breast tumor samples uncovers distinct patterns for aromatase inhibitor resistance |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
ChIP-seq on primary breast cancer tumor samples for Era, H3K4me3, H3K27me3. Patients had a poor or good outcome after aromatase inhibitor treatment. Differential binding patterns between good and poor outcome patients were identified for each marker, predicting response to treatment
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Overall design |
comparing ER, H3K4me3 and H3K27me3 patterns between two breast cancer patient populations
|
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Contributor(s) |
Zwart W, Velds A |
Citation(s) |
24242068, 26484094 |
|
Submission date |
Sep 13, 2012 |
Last update date |
Jul 31, 2019 |
Contact name |
Wilbert Zwart |
Organization name |
NKI
|
Street address |
Plesmanlaan 121
|
City |
Amsterdam |
ZIP/Postal code |
1066CX |
Country |
Netherlands |
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|
Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
Samples (36)
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Relations |
BioProject |
PRJNA175144 |
SRA |
SRP015749 |