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| Status |
Public on Sep 18, 2012 |
| Title |
Impact of STAT5 dosage and binding location on genetic and biological programs activated in mouse mammary epithelium during pregnancy. |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
The transcription factor STAT5 has long been recognized as an important mediator of prolactin induced mammary development during pregnancy. We have used mouse genetics and genome-wide analyses to determine how altering concentrations of STAT5A and STAT5B impacts different target promoters.
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| |
|
| Overall design |
Examination of genome-wide STAT5A, STAT5B, PolII and H3K4me3 in wild type (AABB) and Stat5a-null (BB) mammary tissues.
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| Contributor(s) |
Kang K, Yamaji D, Robinson GW, Hennighausen L |
| Citation(s) |
23275557, 24692510 |
| |
| Submission date |
Sep 17, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Keunsoo Kang |
| E-mail(s) |
[email protected]
|
| Phone |
82-41-550-3456
|
| Organization name |
Dankook University
|
| Department |
Microbiology
|
| Lab |
Computational Biology Lab
|
| Street address |
Dandae-ro 119
|
| City |
Cheonan |
| State/province |
Chungnam |
| ZIP/Postal code |
31116 |
| Country |
South Korea |
| |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (10)
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| Relations |
| BioProject |
PRJNA175393 |
| SRA |
SRP015781 |
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