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| Status |
Public on Sep 17, 2013 |
| Title |
Affymetrix SNP array data for acute lymphoblastic leukemia samples |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by SNP array
|
| Summary |
Development of B-acute lymphoblastic leukemia accompanies with multiple variable mutations. Beside the structural and chromosomal alterations, especially mutations in the regulators of B cell differentiation are common. Around 60% of the B-ALL show deletions of these genes.
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| Overall design |
Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted from cryopreserved diagnostic bone marrow or peripheral blood samples. Copy number analysis of Affymetrix SNP 6.0 arrays was performed for 20 pediatric B-ALL samples and intraindividually matching remission samples which were used as references.
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| Contributor(s) |
Harder L, Horstmann M, Otto B |
| Citation(s) |
24081948 |
| |
| Submission date |
Nov 06, 2012 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Thomas Streichert |
| Organization name |
University Medical Center Hamburg-Eppendorf
|
| Department |
Institute For Clinical Chemistry / Central Laboratories
|
| Street address |
Martinistr. 52, Campus Forschung N27, 2. OG
|
| City |
Hamburg |
| ZIP/Postal code |
D-20246 |
| Country |
Germany |
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| Platforms (1) |
| GPL6801 |
[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array |
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| Samples (40)
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| Relations |
| BioProject |
PRJNA179037 |
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