|
| Status |
Public on Jan 01, 2015 |
| Title |
The effect of MEK inhibition, Interferon beta, and their combination on transcription in melanoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We examined the transcriptional effect of interferon beta, MEK inhibition or their combination on 6 melanoma cell lines
3 cell lines have high basal acitvity of the interferon pathway, and 3 have low basal activity
|
| |
|
| Overall design |
Samples were treated with 50nM of the MEK inhibitor PD901, 1000Units/mL of interferon beta, or their combination and collected 8 hours after treatment
|
| |
|
| Contributor(s) |
Litvin O, Pe'er D |
| Citation(s) |
25684207 |
| |
| Submission date |
Sep 24, 2013 |
| Last update date |
Oct 11, 2016 |
| Contact name |
Dana Pe'er |
| Organization name |
Columbia University
|
| Department |
Biological Sciences
|
| Lab |
Dana Pe'er
|
| Street address |
1212 Amsterdam Ave.
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10027 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL14550 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Probe Name Version) |
|
| Samples (24)
|
|
| This SubSeries is part of SuperSeries: |
| GSE51115 |
The effect of MEK inhibition on transcription in melanoma |
|
| Relations |
| BioProject |
PRJNA221224 |
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