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GEO accession:
Series GSE56504
Query DataSets for GSE56504
Status
Public on Jun 01, 2014
Title
Loss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons
Organisms
Homo sapiens
;
Mus musculus
Experiment type
Expression profiling by array
Summary
This SuperSeries is composed of the SubSeries listed below.
Overall design
Refer to individual Series
Citation(s)
24750229
Submission date
Apr 03, 2014
Last update date
Mar 03, 2017
Contact name
Paul Roy Heath
E-mail(s)
[email protected]
Phone
+44 114 2222254
Organization name
University of Sheffield
Department
Academic Neurology Unit
Lab
Heath
Street address
SITraN, 385a Glossop Road
City
Sheffield
State/province
S. Yorks
ZIP/Postal code
S10 2HQ
Country
United Kingdom
Platforms (2)
GPL5188
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GPL6193
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [probe set (exon) version]
Samples (42)
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More...
GSM838032
Neurologically healthy control 01
GSM838033
Neurologically healthy control 02
GSM838034
Neurologically healthy control 03
GSM838035
Neurologically healthy control 11
GSM838036
Neurologically healthy control 13
GSM838037
Neurologically healthy control 14
GSM838038
ALS with SOD1 mutation patient 28
GSM838039
ALS with SOD1 mutation patient 32
GSM838040
ALS with SOD1 mutation patient 59
GSM838041
ALS with SOD1 mutation patient 99
GSM838042
ALS with TARDBP mutation patient 48
GSM838043
ALS with TARDBP mutation patient 51
GSM838044
ALS with TARDBP mutation patient 55
GSM838045
Sporadic ALS patient 18
GSM838046
Sporadic ALS patient 21
GSM838047
Sporadic ALS patient 23
GSM838048
Sporadic ALS patient 26
GSM838049
Sporadic ALS patient 27
GSM838050
Sporadic ALS patient 31
GSM1362746
Neurologically healthy control LP005/07
GSM1362747
Neurologically healthy control 039/07
GSM1362748
mtC9ORF72 LP045/06
GSM1362749
Neurologically healthy control 056/90
GSM1362750
Neurologically healthy control 080/92
GSM1362751
mtC9ORF72 LP081/09
GSM1362752
sALS 088/89
GSM1362753
sALS 088/96
GSM1362754
Neurologically healthy control 114/93
GSM1362755
Neurologically healthy control 129/94
GSM1362756
mtC9ORF72 155/96
GSM1362757
sALS 193/90
GSM1362920
Control NSC34 cells treated with shGFP 1
GSM1362921
Control NSC34 cells treated with shGFP 2
GSM1362922
Control NSC34 cells treated with shGFP 3
GSM1362923
Control NSC34 cells treated with shGFP 5
GSM1362924
Control NSC34 cells treated with shLuciferase 1
GSM1362925
Control NSC34 cells treated with shLuciferase 2
GSM1362926
Control NSC34 cells treated with shLuciferase 4
GSM1362927
NSC34 cells subjected to shTardbp knockdown 1
GSM1362928
NSC34 cells subjected to shTardbp knockdown 2
GSM1362929
NSC34 cells subjected to shTardbp knockdown 3
GSM1362930
NSC34 cells subjected to shTardbp knockdown 4
This SuperSeries is composed of the following SubSeries:
GSE33855
Loss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons [fibroblasts]
GSE56500
Loss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons [LCM]
GSE56503
Loss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons [NSC34]
Relations
BioProject
PRJNA243543
Download family
Format
SOFT formatted family file(s)
SOFT
MINiML formatted family file(s)
MINiML
Series Matrix File(s)
TXT
Supplementary file
Size
Download
File type/resource
GSE56504_RAW.tar
969.0 Mb
(http)
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