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| Status |
Public on Sep 01, 2014 |
| Title |
Analysis of gene expression changes during long-term induction of EMT in EpRas tumor cells by TGF-b1. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
EMT is a developmental process, which can be reactivated in cancer cells. Cancer cells maintaining EMT in the circulation may have pro-metastatic properties.
We used microarrays to profile EMT-related gene expression changes after 14 d of TGF-b1 treatment.
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| Overall design |
EpRas cells were cultured in standard conditions either in the presence of absence of recombinant TGF-b1 (2 ng/ml) for 14 d. After this period, RNA was isolated from triplicate wells of treated and non-treated cells, and hybridized on Affymetrix microarrays.
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| |
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| Contributor(s) |
Fuxe J, Tabor V, Johansson J |
| Citation(s) |
25674539 |
| |
| Submission date |
Jul 30, 2014 |
| Last update date |
Jun 17, 2019 |
| Contact name |
Jonas Fuxe |
| E-mail(s) |
[email protected]
|
| Phone |
+46852487275
|
| Organization name |
Karolinska Institutet
|
| Department |
Medical Biochemistry and Biophysics
|
| Lab |
Jonas Fuxe
|
| Street address |
Scheeles v. 2
|
| City |
Stockholm |
| ZIP/Postal code |
17177 |
| Country |
Sweden |
| |
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| Platforms (1) |
| GPL11533 |
[MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA257067 |
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