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| Status |
Public on Dec 28, 2015 |
| Title |
mRNA expression profile of MCF7 cells with retroviral inducible expression of ΔNp63α [total RNA] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
MCF7 is a breast adenocarcinoma cell line which exhibits properties of differentiated luminal epithelial cells. ΔNp63α, an N-terminally truncated isoform of p51/p63 protein, plays a critical role in mammary gland development. Here, we inducibly express ΔNp63α in MCF7 cells and studied its role in stemness of breast cancer cells.
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| Overall design |
Expression of ΔNp63α was induced in MCF7 cells with Doxycycline (Dox) for 48 hours. Total RNAs containing microRNAs were isolated. Microarray analysis was performed in Dox- (MCF7-PTO-ΔNp63α-Dox-) and Dox+ (MCF7-PTO-ΔNp63α-Dox+) samples.
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| Contributor(s) |
Amin R, Fujimura Y, Ikawa S |
| Citation(s) |
26704768 |
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| Submission date |
Jan 14, 2015 |
| Last update date |
Dec 28, 2015 |
| Contact name |
Satoshi Kondo |
| Organization name |
Toray Industries,Inc.
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| Department |
New Projects Development Division
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| Street address |
Tebiro 6-10-1
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| City |
Kamakura |
| State/province |
Kanagawa |
| ZIP/Postal code |
248-8555 |
| Country |
Japan |
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| Platforms (1) |
| GPL13915 |
3D-Gene Human Oligo chip 25k V2.1 |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE64955 |
mRNA and miRNA expression profile of MCF7 cells with retroviral inducible expression of ΔNp63α |
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| Relations |
| BioProject |
PRJNA272582 |
