NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE70434 Query DataSets for GSE70434
Status Public on Jul 01, 2015
Title Gene expression data from HEK-293T cells transfected with miR-194 mimics
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Nuclear factor κB (NF-κB) pathway plays an important role in hepatocellular carcinoma (HCC) progression. miR-194 was previously shown to reduce the induction of NF-κB activity upon addition of tumor necrosis factor α (TNFα). To clarify the molecular mechanism responsible for the effect of miR-194 on NF-κB pathway, mRNA microarray assays were performed to identify the genes that were suppressed by miR-194.
 
Overall design HEK-293T cells transfected with miR-194 mimics were cultured for RNA extraction and hybridization on Affymetrix mRNA microarrays. These were compared against the control, which were HEK-293T cells transfected with negative control mimics.
 
Contributor(s) Bao C, Li Y, Huang S, He X
Citation(s) 26221053
Submission date Jul 01, 2015
Last update date Mar 25, 2019
Contact name Chunyang Bao
E-mail(s) [email protected]
Phone 86-21-34777580
Organization name Fudan University
Department Fudan University Shanghai Cancer Center
Street address Shanghai Medical College, Fudan University 1207 Rm., 2# Bldg., 270 Dong An Rd.
City Shanghai
State/province Shanghai
ZIP/Postal code 200032
Country China
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (2)
GSM1754834 HEK-293T_NC
GSM1754835 HEK-293T_194
Relations
BioProject PRJNA288678

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE70434_RAW.tar 9.4 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap