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| Status |
Public on Sep 01, 2018 |
| Title |
Microarray expression data derived from ovaries of women with Polycystic Ovary Syndrome and Female to Male Transexual individuals after treatment with Testosterone |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
This microarray analysis identified differentially regulated expression of 326 genes (p value=<0.05 and fold change of +/-2). Based on these genes, a biological LH network was generated consisting molecules where the significance of the association was measured by Fisher's exact test.
We used microarray gene expression analysis to dissect the LH-induced gene expression in the ovaries of PCOS women.
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| Overall design |
RNA was isolated from ovary biopsies of PCOS women and TSX individuals to investigate LH induced gene expression.
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| Contributor(s) |
Gielen SC, Laven JS, van der Spek P, IJpma A, de Hoon B |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 28, 2016 |
| Last update date |
Sep 02, 2018 |
| Contact name |
Arne IJpma |
| Organization name |
Erasmus MC
|
| Department |
Bioinformatics
|
| Street address |
Dr. Molewaterplein 50
|
| City |
Rotterdam |
| ZIP/Postal code |
3000 CA |
| Country |
Netherlands |
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| Platforms (2) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
| GPL97 |
[HG-U133B] Affymetrix Human Genome U133B Array |
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| Samples (36)
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| Relations |
| BioProject |
PRJNA344763 |
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