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| Status |
Public on Feb 18, 2018 |
| Title |
Regulatory Mechanisms Mediated by DNA methyltransferase 1 link the maternal Environment with the Development of the Embryo |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Epidemiological as well as animal model studies have demonstrated the close relationship that exists between the early maternal developmental environment and the risk of developing metabolic diseases in adulthood. Small birth weight has been shown to be an important marker for this although the molecular mechanisms which mediate these changes are not well understood
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| Overall design |
By using average (50th to 75th) and lower (5th to 25th) percentiles of the normal birth weight range of Wistar rat pups, we show here that the growth of embryos is linked to the early maternal developmental environment
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| Contributor(s) |
Prabakaran AD, Karakkat JV, Vijayan R, Chalissery J, Ibrahim MF, Kaimala S, Adeghate EA, Al-Marzouqi AH, Ansari SA, EPK M, David SE |
| Citation(s) |
29434026 |
| |
| Submission date |
May 12, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Ranjit Vijayan |
| Organization name |
United Arab Emirates University
|
| Department |
Biology
|
| Street address |
PO Box 15551
|
| City |
Al Ain |
| State/province |
Abu Dhabi |
| ZIP/Postal code |
15551 |
| Country |
United Arab Emirates |
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| Platforms (1) |
| GPL19519 |
NimbleGen Rat 12x135K gene expression array [100718_Rat_HX12_expr] |
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| Samples (12)
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| GSM2616342 |
Low birth weight adult rats on normal diet 1 |
| GSM2616343 |
Low birth weight adult rats on normal diet 2 |
| GSM2616344 |
Low birth weight adult rats on normal diet 3 |
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| Relations |
| BioProject |
PRJNA386448 |
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