|
| Status |
Public on Aug 02, 2024 |
| Title |
P99 | 001 | TME |
| Sample type |
protein |
| |
|
| Source name |
HNSCC
|
| Organism |
Homo sapiens |
| Characteristics |
tissue: HNSCC
roi.x.coordinate: 0
roi.y.coordinate: 0
nuclei.count: 970
qc.flags: NA
bestresponse: PD
roi_qc: TRUE
slide_tissue_qc: TRUE
pathway: Nivolumab
mortality: Y
age: 72
Sex: Male
smokingstatus: Current
pfs: 3 mos
lib_size: 7979.125183336
countofloweprgene: 1
percentofloweprgene: 1.2987012987013
foi: TME_PD
ruv_w1: -0.0749400649714727
ruv_w2: -0.0164483573529823
responsesintumour: TME
responsesintme: PD
|
| Extracted molecule |
protein |
| Extraction protocol |
Clinical FFPE samples on individual slides were obtained with appropriate ethics approval
|
| Label |
N/A
|
| Label protocol |
DSP experiments were performed as per manufacturers DSP Slide Prep User Manual
|
| |
|
| Hybridization protocol |
DSP eluates were hybridised as per manufacturers instructions in nCounter Readout User Manual.
|
| Scan protocol |
Hybridised samples were loaded into Nanostring prep station and processed as per DSP Slide Prep User Manual. N counter was performed with default parameters, and counts from Ncounter uploaded back to DSP instrument
|
| Description |
norm_QC.csv
|
| Data processing |
Counts were aligned and ERCC corrected automatically on the DSP instrument. This QC data was exported for analysis.
|
| |
|
| Submission date |
Feb 26, 2024 |
| Last update date |
Aug 02, 2024 |
| Contact name |
Habib Sadeghirad |
| E-mail(s) |
[email protected]
|
| Phone |
0451319292
|
| Organization name |
The University of Queensland
|
| Street address |
37 Kent St, Woolloongabba, 37 Kent St, Woolloongabba
|
| City |
Brisbane |
| State/province |
Queensland |
| ZIP/Postal code |
4102 |
| Country |
Australia |
| |
|
| Platform ID |
GPL34246 |
| Series (1) |
| GSE259280 |
Transcriptomic and proteomic spatial profiling of tertiary lymphoid aggregates in head and neck cancer reveal spatial tissue dynamics and profiles associated with immunotherapy response [protein] |
|
