ProfileGDS5029 / 225344_at
TitleSW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
OrganismHomo sapiens


untreated DMSO MEK inhibitor tankyrase inhibitor tankyrase and MEK inhibitors control 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours 4 hours 16 hours GSM1340521 GSM1340522 GSM1340523 GSM1340524 GSM1340531 GSM1340532 GSM1340527 GSM1340528 GSM1340535 GSM1340536 GSM1340525 GSM1340526 GSM1340533 GSM1340534 GSM1340529 GSM1340530 GSM1340537 GSM1340538 83% 83% 77% 77% 78% 79% 84% 83% 85% 84% 78% 78% 79% 80% 83% 84% 85% 86% sort by protocol sort by time Gene Expression Profile
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SampleTitleValueRank
GSM1340521parental biological replicate 1310.483
GSM1340522parental biological replicate 2304.483
GSM1340523DMSO 4h biological replicate 1169.677
GSM1340524DMSO 4h biological replicate 2157.977
GSM1340531DMSO 16h biological replicate 1172.978
GSM1340532DMSO 16h biological replicate 2194.279
GSM1340527MEKi 4h biological replicate 1319.584
GSM1340528MEKi 4h biological replicate 2288.183
GSM1340535MEKi 16h biological replicate 135185
GSM1340536MEKi 16h biological replicate 232084
GSM1340525TNKSi 4h biological replicate 1175.178
GSM1340526TNKSi 4h biological replicate 2180.378
GSM1340533TNKSi 16h biological replicate 1196.179
GSM1340534TNKSi 16h biological replicate 220880
GSM1340529Combo 4h biological replicate 128583
GSM1340530Combo 4h biological replicate 231784
GSM1340537Combo 16h biological replicate 1363.885
GSM1340538Combo 16h biological replicate 2391.186